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- W4286499619 endingPage "10079" @default.
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- W4286499619 abstract "We report the synthesis, chemical properties, and disulfide bond-reducing performance of a dithiol called NACMEAA, conceived as a hybrid of two biologically relevant thiols: cysteine and cysteamine. NACMEAA is conveniently prepared from inexpensive l-cystine in an efficient manner. As a nonvolatile, highly soluble, and neutral compound at physiological pH with the first thiol pKa value of 8.0, NACMEAA is reactive and user-friendly. We also demonstrate that NACMEAA reduces disulfide bonds in GSSG and lysozyme." @default.
- W4286499619 created "2022-07-22" @default.
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- W4286499619 date "2022-07-21" @default.
- W4286499619 modified "2023-09-30" @default.
- W4286499619 title "Dithiol Based on <scp>l</scp>-Cysteine and Cysteamine as a Disulfide-Reducing Agent" @default.
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- W4286499619 doi "https://doi.org/10.1021/acs.joc.2c01050" @default.
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