FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286500684> ?p ?o ?g. }

• W4286500684 abstract "Transplant-associated thrombotic microangiopathy (TA-TMA) is an under-recognized yet potentially devastating complication of hematopoietic stem cell transplantation (HSCT) which had increased awareness in recent years. This report summarizes the demographics and outcomes of pediatric TA-TMA in Hong Kong.All patients aged below 18 years who underwent HSCT in the Hong Kong Children's Hospital and were diagnosed to have TA-TMA during the 2-year period from April 1, 2019 to March 31, 2021 were included.A total of 73 transplants (51 allogeneic and 22 autologous) in 63 patients had been performed. Six patients (four males and two females) developed TA-TMA at a median duration of 2.5 months post-HSCT. The incidence rate was 9.52%. Of the six TA-TMA patients, five underwent allogenic one underwent autologous HSCT, respectively. Three of them were histologically proven. All four patients with cyclosporine had stopped the drug once TA-TMA was suspected. Median six doses of eculizumab were administered to five out of six patients. Three patients died (two due to fungal infection and one due to acute-on-chronic renal failure) within 3 months upon diagnosis of TA-TMA. Among three survivors, two stabilized with mild stage 2 chronic kidney disease (CKD) while the other suffered from stage 5 end-stage CKD requiring lifelong dialysis.In conclusion, recognition and diagnosis of TA-TMA are challenging. Early recognition and prompt administration of complement blockage with eculizumab may be beneficial in selected cases. Further prospective research studies are recommended to improve the management and outcomes of TA-TMA." @default.
• W4286500684 created "2022-07-22" @default.
• W4286500684 creator A5007152098 @default.
• W4286500684 creator A5010231188 @default.
• W4286500684 creator A5023769086 @default.
• W4286500684 creator A5037615314 @default.
• W4286500684 creator A5042430428 @default.
• W4286500684 creator A5044383042 @default.
• W4286500684 creator A5058437494 @default.
• W4286500684 creator A5062964407 @default.
• W4286500684 creator A5072072056 @default.
• W4286500684 creator A5073520793 @default.
• W4286500684 date "2022-07-21" @default.
• W4286500684 modified "2023-10-16" @default.
• W4286500684 title "Epidemiology and outcomes of pediatric transplant‐associated thrombotic microangiopathy in Hong Kong" @default.
• W4286500684 cites W109217714 @default.
• W4286500684 cites W1676794103 @default.
• W4286500684 cites W1972848999 @default.
• W4286500684 cites W1977035416 @default.
• W4286500684 cites W1993215990 @default.
• W4286500684 cites W2007003377 @default.
• W4286500684 cites W2008607429 @default.
• W4286500684 cites W2025908166 @default.
• W4286500684 cites W2031845095 @default.
• W4286500684 cites W2037119492 @default.
• W4286500684 cites W2041592708 @default.
• W4286500684 cites W2052963776 @default.
• W4286500684 cites W2061771861 @default.
• W4286500684 cites W2082814420 @default.
• W4286500684 cites W2085290177 @default.
• W4286500684 cites W2090291536 @default.
• W4286500684 cites W2092646091 @default.
• W4286500684 cites W2093903773 @default.
• W4286500684 cites W2095078549 @default.
• W4286500684 cites W2104989059 @default.
• W4286500684 cites W2110555587 @default.
• W4286500684 cites W2110611041 @default.
• W4286500684 cites W2117803220 @default.
• W4286500684 cites W2141010787 @default.
• W4286500684 cites W2150192501 @default.
• W4286500684 cites W2150471755 @default.
• W4286500684 cites W2150825954 @default.
• W4286500684 cites W2168610288 @default.
• W4286500684 cites W2335781036 @default.
• W4286500684 cites W2343260633 @default.
• W4286500684 cites W2343579390 @default.
• W4286500684 cites W2569872308 @default.
• W4286500684 cites W2743895474 @default.
• W4286500684 cites W2747721206 @default.
• W4286500684 cites W2761108028 @default.
• W4286500684 cites W2793137791 @default.
• W4286500684 cites W2887339279 @default.
• W4286500684 cites W2898569324 @default.
• W4286500684 cites W2923881376 @default.
• W4286500684 cites W3031671182 @default.
• W4286500684 cites W3033416765 @default.
• W4286500684 cites W3092452058 @default.
• W4286500684 cites W3107312345 @default.
• W4286500684 cites W3193704441 @default.
• W4286500684 cites W3196795829 @default.
• W4286500684 cites W3215978772 @default.
• W4286500684 doi "https://doi.org/10.1111/petr.14366" @default.
• W4286500684 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35860972" @default.
• W4286500684 hasPublicationYear "2022" @default.
• W4286500684 type Work @default.
• W4286500684 citedByCount "2" @default.
• W4286500684 countsByYear W42865006842023 @default.
• W4286500684 crossrefType "journal-article" @default.
• W4286500684 hasAuthorship W4286500684A5007152098 @default.
• W4286500684 hasAuthorship W4286500684A5010231188 @default.
• W4286500684 hasAuthorship W4286500684A5023769086 @default.
• W4286500684 hasAuthorship W4286500684A5037615314 @default.
• W4286500684 hasAuthorship W4286500684A5042430428 @default.
• W4286500684 hasAuthorship W4286500684A5044383042 @default.
• W4286500684 hasAuthorship W4286500684A5058437494 @default.
• W4286500684 hasAuthorship W4286500684A5062964407 @default.
• W4286500684 hasAuthorship W4286500684A5072072056 @default.
• W4286500684 hasAuthorship W4286500684A5073520793 @default.
• W4286500684 hasConcept C107130276 @default.
• W4286500684 hasConcept C111684460 @default.
• W4286500684 hasConcept C120665830 @default.
• W4286500684 hasConcept C121332964 @default.
• W4286500684 hasConcept C126322002 @default.
• W4286500684 hasConcept C141071460 @default.
• W4286500684 hasConcept C146357865 @default.
• W4286500684 hasConcept C151730666 @default.
• W4286500684 hasConcept C159654299 @default.
• W4286500684 hasConcept C187212893 @default.
• W4286500684 hasConcept C203014093 @default.
• W4286500684 hasConcept C2777408962 @default.
• W4286500684 hasConcept C2777878052 @default.
• W4286500684 hasConcept C2777991916 @default.
• W4286500684 hasConcept C2778653478 @default.
• W4286500684 hasConcept C2779134260 @default.
• W4286500684 hasConcept C2779978075 @default.
• W4286500684 hasConcept C2911091166 @default.
• W4286500684 hasConcept C61511704 @default.
• W4286500684 hasConcept C71924100 @default.
• W4286500684 hasConcept C81182388 @default.
• W4286500684 hasConcept C86803240 @default.

• next