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- W4286510210 abstract "Pimitespib (PIMI), also known as TAS-116, is a novel class of orally active selective heat shock protein 90 (HSP90) inhibitor. KIT and PDGFRA are clients of HSP90 for their functional stability. A phase II trial showed clinical activity of PIMI in patients (pts) with advanced gastrointestinal stromal tumor (GIST) refractory to standard treatments. This phase III trial evaluated the efficacy and safety of PIMI. (JapicCTI-184094)." @default.
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- W4286510210 date "2022-07-01" @default.
- W4286510210 modified "2023-09-29" @default.
- W4286510210 title "PS4-3 A phase III trial of pimitespib (TAS-116) in patients with advanced gastrointestinal stromal tumor: CHAPTER-GIST-301" @default.
- W4286510210 doi "https://doi.org/10.1016/j.annonc.2022.05.071" @default.
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