FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286560377> ?p ?o ?g. }

• W4286560377 abstract "As the treatment target, the imaging information and histologic characteristics of the thrombus may differ according to the stroke subtype. This study aimed to provide the correlative study of stroke etiology with the non-contrast CT, and histological composition of retrieved clots in acute ischemic stroke (AIS).A total of 94 patients with AIS who underwent the endovascular treatment with successfully retrieved clots from January 2017 to October 2020 were enrolled in the present study. Histological analysis was performed using hematoxylin and eosin (H&E) staining and immunostaining with CD3, CD20, CD105, and actin antibodies. CT obtained at the patients' admission was to measure the attenuation and volume of all thrombus.A total of 94 subjects were included in this study. Fifty-six patients were classified as cardioembolic (CE), and 38 were classified with large-artery atherosclerosis (LAA). The subjects with LAA tend to exhibit higher actin and CD105 levels, and lower Hounsfield Unit (HU) values than subjects with CE. After adjusting for confounders, the actin was positively correlated with CD105 but not with HU values. Logistics regression shows actin was valuable for the prediction of LAA (OR, 1.148; 95% CI, 1.075-1.227; p < 0.001), even adjusted for age, sex, and intervention type (OR, 1.129; 95% CI, 1.048-1.216; p = 0.001), CT density and CD105 (OR, 1.161; 95% CI, 1.056-1.277; p = 0.002). Actin levels have a strong accuracy in differentiating LAA from CE, especially combined with CT density and CD105, which yielded a sensitivity of 63.2%, a specificity of 89.3%, with the area under the curve (AUC) at 0.821 (95% CI, 0.731-0.912).Our findings suggest that actin's level was a major factor differentiating atherothrombotic origin strokes from the cardioembolic stroke.ChiCTR2100051173." @default.
• W4286560377 created "2022-07-22" @default.
• W4286560377 creator A5004858099 @default.
• W4286560377 creator A5032764121 @default.
• W4286560377 creator A5044256713 @default.
• W4286560377 creator A5054358636 @default.
• W4286560377 creator A5055733933 @default.
• W4286560377 creator A5057403010 @default.
• W4286560377 creator A5069646903 @default.
• W4286560377 creator A5090134315 @default.
• W4286560377 date "2022-07-22" @default.
• W4286560377 modified "2023-10-01" @default.
• W4286560377 title "High Actin Expression in Thrombus of Acute Ischemic Stroke Can Be a Biomarker of Atherothrombotic Origin Stroke" @default.
• W4286560377 cites W1518670039 @default.
• W4286560377 cites W1523655008 @default.
• W4286560377 cites W1963876174 @default.
• W4286560377 cites W1974997758 @default.
• W4286560377 cites W2005144667 @default.
• W4286560377 cites W2013222196 @default.
• W4286560377 cites W2014074474 @default.
• W4286560377 cites W2037690972 @default.
• W4286560377 cites W2046966520 @default.
• W4286560377 cites W2049433850 @default.
• W4286560377 cites W2066915043 @default.
• W4286560377 cites W2067395123 @default.
• W4286560377 cites W2084388883 @default.
• W4286560377 cites W2091588217 @default.
• W4286560377 cites W2099057755 @default.
• W4286560377 cites W2111487638 @default.
• W4286560377 cites W2114885922 @default.
• W4286560377 cites W2132770778 @default.
• W4286560377 cites W2134094618 @default.
• W4286560377 cites W2136873455 @default.
• W4286560377 cites W2138595885 @default.
• W4286560377 cites W2163832548 @default.
• W4286560377 cites W2172571651 @default.
• W4286560377 cites W2220705223 @default.
• W4286560377 cites W2229480159 @default.
• W4286560377 cites W2274924551 @default.
• W4286560377 cites W2282946060 @default.
• W4286560377 cites W2319719887 @default.
• W4286560377 cites W2345595739 @default.
• W4286560377 cites W2407452807 @default.
• W4286560377 cites W2464396699 @default.
• W4286560377 cites W2594707584 @default.
• W4286560377 cites W2605484715 @default.
• W4286560377 cites W2625088739 @default.
• W4286560377 cites W2784146546 @default.
• W4286560377 cites W2792743386 @default.
• W4286560377 cites W2804956073 @default.
• W4286560377 cites W2887311144 @default.
• W4286560377 cites W2895955008 @default.
• W4286560377 cites W2899736836 @default.
• W4286560377 cites W2940560793 @default.
• W4286560377 cites W2946999794 @default.
• W4286560377 cites W2953282350 @default.
• W4286560377 cites W3025980212 @default.
• W4286560377 cites W3113178943 @default.
• W4286560377 cites W3157954008 @default.
• W4286560377 cites W3203095413 @default.
• W4286560377 doi "https://doi.org/10.3389/fneur.2022.896428" @default.
• W4286560377 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35937070" @default.
• W4286560377 hasPublicationYear "2022" @default.
• W4286560377 type Work @default.
• W4286560377 citedByCount "2" @default.
• W4286560377 countsByYear W42865603772023 @default.
• W4286560377 crossrefType "journal-article" @default.
• W4286560377 hasAuthorship W4286560377A5004858099 @default.
• W4286560377 hasAuthorship W4286560377A5032764121 @default.
• W4286560377 hasAuthorship W4286560377A5044256713 @default.
• W4286560377 hasAuthorship W4286560377A5054358636 @default.
• W4286560377 hasAuthorship W4286560377A5055733933 @default.
• W4286560377 hasAuthorship W4286560377A5057403010 @default.
• W4286560377 hasAuthorship W4286560377A5069646903 @default.
• W4286560377 hasAuthorship W4286560377A5090134315 @default.
• W4286560377 hasBestOaLocation W42865603771 @default.
• W4286560377 hasConcept C10205521 @default.
• W4286560377 hasConcept C119060515 @default.
• W4286560377 hasConcept C125473707 @default.
• W4286560377 hasConcept C126322002 @default.
• W4286560377 hasConcept C126838900 @default.
• W4286560377 hasConcept C127413603 @default.
• W4286560377 hasConcept C142724271 @default.
• W4286560377 hasConcept C164705383 @default.
• W4286560377 hasConcept C185592680 @default.
• W4286560377 hasConcept C187954543 @default.
• W4286560377 hasConcept C204232928 @default.
• W4286560377 hasConcept C2780645631 @default.
• W4286560377 hasConcept C2781197716 @default.
• W4286560377 hasConcept C2781362458 @default.
• W4286560377 hasConcept C28328180 @default.
• W4286560377 hasConcept C54355233 @default.
• W4286560377 hasConcept C544519230 @default.
• W4286560377 hasConcept C55493867 @default.
• W4286560377 hasConcept C6061869 @default.
• W4286560377 hasConcept C71924100 @default.
• W4286560377 hasConcept C78519656 @default.
• W4286560377 hasConcept C86803240 @default.
• W4286560377 hasConcept C90924648 @default.
• W4286560377 hasConceptScore W4286560377C10205521 @default.

• next