FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286560424> ?p ?o ?g. }

• W4286560424 abstract "It is poorly understood how the physical state of emulsified triacylglycerol (TAG) alters colloidal behavior in the gastrointestinal tract to modulate lipid digestion and absorption. We, therefore, aimed to investigate the individual and combined effects on fatty acid (FA) bioaccessibility using the dynamic TIM-1 in vitro digestion model and integrate the results with those from a human clinical study. Four 20% oil-in-water emulsions with overlapping particle size distributions contained either partially crystalline solid (palm stearin) or liquid (palm olein) lipid droplets at 37°C and either the colloidally acid-stable Tween 80 (2.2%) or acid-unstable Span 60 (2.5%) emulsifier. Experimental meals were fed to the TIM-1, and jejunal and ileal dialysates were analyzed over 6 h to measure free FA concentration. Cumulative FA bioaccessibility was significantly higher for the liquid stable emulsion compared to all others ( p &lt; 0.05), which did not differ ( p &gt; 0.05). Emulsified TAG physical state was associated with differences in overall bioaccessibility (higher for liquid state TAG) in the colloidally stable emulsions, but this difference was blunted in droplets susceptible to acidic flocculation. In contrast, human postprandial TAG concentrations did not differ significantly between the emulsions. The discrepancy may relate to differences in in vivo gastric emptying (GE) as evidenced by ultrasonography. When the in vivo differences in GE were accounted for in follow-up TIM-1 experiments, the findings aligned more closely. Cumulative FA bioaccessibility for the liquid stable emulsion no longer differed significantly from the other emulsions, and SU’s bioaccessibility was the lowest, consistent with the in vivo observations. This work highlights the potential for TAG physical state and colloidal stability to interactively alter behavior in the gastrointestinal tract with implications for FA absorption, and the importance of establishing and improving in vitro–in vivo correlations in food-nutrition research." @default.
• W4286560424 created "2022-07-22" @default.
• W4286560424 creator A5019866724 @default.
• W4286560424 creator A5042376599 @default.
• W4286560424 creator A5053274927 @default.
• W4286560424 creator A5065477296 @default.
• W4286560424 creator A5068897275 @default.
• W4286560424 creator A5072760018 @default.
• W4286560424 creator A5076432773 @default.
• W4286560424 creator A5089200875 @default.
• W4286560424 date "2022-07-22" @default.
• W4286560424 modified "2023-10-17" @default.
• W4286560424 title "Palm Lipid Emulsion Droplet Crystallinity and Gastric Acid Stability in Relation to in vitro Bioaccessibility and in vivo Gastric Emptying" @default.
• W4286560424 cites W130193209 @default.
• W4286560424 cites W1841462180 @default.
• W4286560424 cites W1980922323 @default.
• W4286560424 cites W1982984872 @default.
• W4286560424 cites W1986904984 @default.
• W4286560424 cites W1988967895 @default.
• W4286560424 cites W2005520712 @default.
• W4286560424 cites W2015918699 @default.
• W4286560424 cites W2033372350 @default.
• W4286560424 cites W2045658046 @default.
• W4286560424 cites W2051960512 @default.
• W4286560424 cites W2063369457 @default.
• W4286560424 cites W2066652031 @default.
• W4286560424 cites W2069136529 @default.
• W4286560424 cites W2070511172 @default.
• W4286560424 cites W2073349849 @default.
• W4286560424 cites W2095033489 @default.
• W4286560424 cites W2097086470 @default.
• W4286560424 cites W2106493094 @default.
• W4286560424 cites W2106762957 @default.
• W4286560424 cites W2111656834 @default.
• W4286560424 cites W2118004416 @default.
• W4286560424 cites W2124171370 @default.
• W4286560424 cites W2131485719 @default.
• W4286560424 cites W2132158826 @default.
• W4286560424 cites W2148930131 @default.
• W4286560424 cites W2149098049 @default.
• W4286560424 cites W2160446463 @default.
• W4286560424 cites W2168526937 @default.
• W4286560424 cites W2169804397 @default.
• W4286560424 cites W2294742495 @default.
• W4286560424 cites W2341786551 @default.
• W4286560424 cites W2409743725 @default.
• W4286560424 cites W2486443429 @default.
• W4286560424 cites W2756185395 @default.
• W4286560424 cites W2756610950 @default.
• W4286560424 cites W2765847216 @default.
• W4286560424 cites W2789540981 @default.
• W4286560424 cites W2891665266 @default.
• W4286560424 cites W2894080462 @default.
• W4286560424 cites W2901899012 @default.
• W4286560424 cites W2979627926 @default.
• W4286560424 cites W3000000262 @default.
• W4286560424 cites W3033596423 @default.
• W4286560424 cites W3036606567 @default.
• W4286560424 cites W3036681511 @default.
• W4286560424 cites W3157151407 @default.
• W4286560424 cites W4599924 @default.
• W4286560424 doi "https://doi.org/10.3389/fnut.2022.940045" @default.
• W4286560424 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35938112" @default.
• W4286560424 hasPublicationYear "2022" @default.
• W4286560424 type Work @default.
• W4286560424 citedByCount "0" @default.
• W4286560424 crossrefType "journal-article" @default.
• W4286560424 hasAuthorship W4286560424A5019866724 @default.
• W4286560424 hasAuthorship W4286560424A5042376599 @default.
• W4286560424 hasAuthorship W4286560424A5053274927 @default.
• W4286560424 hasAuthorship W4286560424A5065477296 @default.
• W4286560424 hasAuthorship W4286560424A5068897275 @default.
• W4286560424 hasAuthorship W4286560424A5072760018 @default.
• W4286560424 hasAuthorship W4286560424A5076432773 @default.
• W4286560424 hasAuthorship W4286560424A5089200875 @default.
• W4286560424 hasBestOaLocation W42865604241 @default.
• W4286560424 hasConcept C134018914 @default.
• W4286560424 hasConcept C150903083 @default.
• W4286560424 hasConcept C181199279 @default.
• W4286560424 hasConcept C185592680 @default.
• W4286560424 hasConcept C207001950 @default.
• W4286560424 hasConcept C2777504413 @default.
• W4286560424 hasConcept C2778123984 @default.
• W4286560424 hasConcept C2778199505 @default.
• W4286560424 hasConcept C2779306644 @default.
• W4286560424 hasConcept C2779422922 @default.
• W4286560424 hasConcept C2779697368 @default.
• W4286560424 hasConcept C2781357212 @default.
• W4286560424 hasConcept C2910483411 @default.
• W4286560424 hasConcept C3020479747 @default.
• W4286560424 hasConcept C31903555 @default.
• W4286560424 hasConcept C43617362 @default.
• W4286560424 hasConcept C543025807 @default.
• W4286560424 hasConcept C55493867 @default.
• W4286560424 hasConcept C55924715 @default.
• W4286560424 hasConcept C86803240 @default.
• W4286560424 hasConceptScore W4286560424C134018914 @default.
• W4286560424 hasConceptScore W4286560424C150903083 @default.
• W4286560424 hasConceptScore W4286560424C181199279 @default.
• W4286560424 hasConceptScore W4286560424C185592680 @default.

• next