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• W4286563973 abstract "Multiple sclerosis (MS) is a central nervous system inflammatory illness that begins with immune system dysregulation and impairs information flow inside the brain as well as between the brain and the rest of the body. The cause of MS is yet unknown. The interplay of genetic predispositions with environmental/lifestyle factors, such as smoking, obesity, viral exposure, and insufficient sun exposure, has led to numerous theories. This is reinforced by a major discovery of gene–environment (GxE) interaction, which could provide information on the disease’s molecular pathways to aid in the identification of new therapy and preventative strategies, as well as steer disease exploration to new lifestyle suggestions. While some persons with the major susceptibility to MS have a human leukocyte antigen (HLA) Class II gene, according to genetic studies. We will cover recent studies relating to several genetic, environmental, and lifestyle factors, as well as their impact on MS, in this chapter." @default.
• W4286563973 created "2022-07-22" @default.
• W4286563973 creator A5001872716 @default.
• W4286563973 creator A5019774032 @default.
• W4286563973 creator A5088097923 @default.
• W4286563973 date "2022-07-13" @default.
• W4286563973 modified "2023-10-18" @default.
• W4286563973 title "Exploring the Effect of Genetic, Environmental and Lifestyle Factors on Multiple Sclerosis Susceptibility" @default.
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