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- W4286564991 abstract "Application of the traditional immunochromatographic assay (ICGA) has been limited by its poor sensitivity. The objective of this study was to increase the sensitivity of the traditional ICGA. A dual-mode ICGA (D-M ICGA) was developed by combining a nanozyme-assisted signal-amplification strategy with a magnetic-nanoparticle-based flow-speed-control strategy. Salmonella typhimurium can be detected simultaneously based on color and magnetic signals in the detection area of the D-M ICGA strip. The calculated limits of detection of 50 cfu·mL−1 and 75 cfu·mL−1 in the color and magnetic modes, respectively, were approximately 1000 times lower than those of the traditional ICGA. The selectivity and practical applicability of the D-M ICGA were also confirmed in this study. The results prove that the D-M ICGA is an assay that could be used for Salmonella typhimurium detection and can be easily adapted to detect other pathogenic bacteria." @default.
- W4286564991 created "2022-07-22" @default.
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- W4286564991 date "2022-12-01" @default.
- W4286564991 modified "2023-10-17" @default.
- W4286564991 title "Improving the sensitivity of lateral flow immunoassay for Salmonella typhimurium detection via flow-rate regulation" @default.
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- W4286564991 doi "https://doi.org/10.1016/j.foodchem.2022.133756" @default.
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