Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286586451> ?p ?o ?g. }
- W4286586451 endingPage "1785" @default.
- W4286586451 startingPage "1785" @default.
- W4286586451 abstract "The main challenge in diagnosing and managing thoracic aortic aneurysm and dissection (TAA/D) is represented by the early detection of a disease that is both deadly and elusive, as it generally grows asymptomatically prior to rupture, leading to death in the majority of cases. Gender differences exist in aortic dissection in terms of incidence and treatment options. Efforts have been made to identify biomarkers that may help in early diagnosis and in detecting those patients at a higher risk of developing life-threatening complications. As soon as the hereditability of the TAA/D was demonstrated, several genetic factors were found to be associated with both the syndromic and non-syndromic forms of the disease, and they currently play a role in patient diagnosis/prognosis and management-guidance purposes. Likewise, circulating biomarker could represent a valuable resource in assisting the diagnosis, and several studies have attempted to identify specific molecules that may help with risk stratification outside the emergency department. Even if promising, those data lack specificity/sensitivity, and, in most cases, they need more testing before entering the clinical arena. This review summarizes the state of the art of the laboratory in TAA/D diagnostics, with particular reference to the current and future role of molecular-genetic testing." @default.
- W4286586451 created "2022-07-22" @default.
- W4286586451 creator A5011842156 @default.
- W4286586451 creator A5021843146 @default.
- W4286586451 creator A5033872256 @default.
- W4286586451 creator A5044487024 @default.
- W4286586451 creator A5052719563 @default.
- W4286586451 creator A5070057174 @default.
- W4286586451 creator A5072184049 @default.
- W4286586451 creator A5076179755 @default.
- W4286586451 creator A5082934399 @default.
- W4286586451 creator A5090150666 @default.
- W4286586451 date "2022-07-22" @default.
- W4286586451 modified "2023-10-05" @default.
- W4286586451 title "Tracking an Elusive Killer: State of the Art of Molecular-Genetic Knowledge and Laboratory Role in Diagnosis and Risk Stratification of Thoracic Aortic Aneurysm and Dissection" @default.
- W4286586451 cites W1494519116 @default.
- W4286586451 cites W1590960158 @default.
- W4286586451 cites W175967323 @default.
- W4286586451 cites W1828537510 @default.
- W4286586451 cites W1828969851 @default.
- W4286586451 cites W1841315312 @default.
- W4286586451 cites W1875345172 @default.
- W4286586451 cites W1917149672 @default.
- W4286586451 cites W1948796298 @default.
- W4286586451 cites W1959633524 @default.
- W4286586451 cites W1961370442 @default.
- W4286586451 cites W1966119039 @default.
- W4286586451 cites W1967717800 @default.
- W4286586451 cites W1968304646 @default.
- W4286586451 cites W1976250864 @default.
- W4286586451 cites W1977348040 @default.
- W4286586451 cites W1977824141 @default.
- W4286586451 cites W1979522701 @default.
- W4286586451 cites W1980628339 @default.
- W4286586451 cites W1981943396 @default.
- W4286586451 cites W1983394965 @default.
- W4286586451 cites W1984525830 @default.
- W4286586451 cites W1985184637 @default.
- W4286586451 cites W1987244708 @default.
- W4286586451 cites W1988276885 @default.
- W4286586451 cites W1988330143 @default.
- W4286586451 cites W1992789565 @default.
- W4286586451 cites W1995088425 @default.
- W4286586451 cites W1997035995 @default.
- W4286586451 cites W2000028229 @default.
- W4286586451 cites W2004074414 @default.
- W4286586451 cites W2004553444 @default.
- W4286586451 cites W2004672271 @default.
- W4286586451 cites W2006036905 @default.
- W4286586451 cites W2006337259 @default.
- W4286586451 cites W2008297386 @default.
- W4286586451 cites W2008586203 @default.
- W4286586451 cites W2009154640 @default.
- W4286586451 cites W2011196754 @default.
- W4286586451 cites W2012315214 @default.
- W4286586451 cites W2012409690 @default.
- W4286586451 cites W2013858962 @default.
- W4286586451 cites W2014293513 @default.
- W4286586451 cites W2014535603 @default.
- W4286586451 cites W2017128604 @default.
- W4286586451 cites W2022058039 @default.
- W4286586451 cites W2023810702 @default.
- W4286586451 cites W2024025359 @default.
- W4286586451 cites W2024699799 @default.
- W4286586451 cites W2026367729 @default.
- W4286586451 cites W2030732677 @default.
- W4286586451 cites W2030840013 @default.
- W4286586451 cites W2036951324 @default.
- W4286586451 cites W2037817605 @default.
- W4286586451 cites W2038136158 @default.
- W4286586451 cites W2040832427 @default.
- W4286586451 cites W2041025244 @default.
- W4286586451 cites W2041713378 @default.
- W4286586451 cites W2041938961 @default.
- W4286586451 cites W2043568270 @default.
- W4286586451 cites W2047493201 @default.
- W4286586451 cites W2048631747 @default.
- W4286586451 cites W2049137539 @default.
- W4286586451 cites W2050606054 @default.
- W4286586451 cites W2052652609 @default.
- W4286586451 cites W2052864143 @default.
- W4286586451 cites W2053146170 @default.
- W4286586451 cites W2054351373 @default.
- W4286586451 cites W2056973598 @default.
- W4286586451 cites W2057825183 @default.
- W4286586451 cites W2058498186 @default.
- W4286586451 cites W2060017932 @default.
- W4286586451 cites W2060737779 @default.
- W4286586451 cites W2065856890 @default.
- W4286586451 cites W2069153693 @default.
- W4286586451 cites W2073486607 @default.
- W4286586451 cites W2077179440 @default.
- W4286586451 cites W2077710157 @default.
- W4286586451 cites W2077910465 @default.
- W4286586451 cites W2083723945 @default.
- W4286586451 cites W2084533380 @default.
- W4286586451 cites W2087231535 @default.
- W4286586451 cites W2090682011 @default.