FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286586551> ?p ?o ?g. }

• W4286586551 endingPage "35113" @default.
• W4286586551 startingPage "35105" @default.
• W4286586551 abstract "Insect growth regulators (IGRs) guide animal development through injection, oral feeding, or topical application. Among them, lufenuron is a widely used insect cuticle inhibitor but only shows a gastric toxic effect. Lacking contact toxicity limits the effective utilization when spraying the lufenuron pesticide. To overcome this shortcoming, a nanocarrier (star polycation, SPc)-based transdermal delivery system was applied to improve the penetrability and contact toxicity of lufenuron. The fluoride groups in lufenuron could interact with the tertiary amines in the branch-chain of the SPc through electrostatic interaction to form a lufenuron/SPc complex. The above interaction reduced the particle size of lufenuron from 933 to 70 nm. Interestingly, the contact toxicity of SPc-loaded lufenuron was remarkably improved with effects of higher larval mortality and lower egg hatching rate of the devastating pest fall armyworm. The physiological and molecular toxic mechanism was revealed by RNA-Seq analysis. The SPc-loaded lufenuron apparently down-regulated cuticle-related genes and thus inhibited insect cuticle formation. Such contact toxicity was achieved by the transdermal nanodelivery of lufenuron, which up-regulated endocytosis-related genes for drug uptake. This study is the first successful application of a nanoparticle-mediated transdermal delivery system to explore the contact toxicity of an IGR, which alters the IRG’s action mode from oral feeding to topical application." @default.
• W4286586551 created "2022-07-22" @default.
• W4286586551 creator A5008199746 @default.
• W4286586551 creator A5011088053 @default.
• W4286586551 creator A5017277291 @default.
• W4286586551 creator A5018351094 @default.
• W4286586551 creator A5038187304 @default.
• W4286586551 creator A5065592637 @default.
• W4286586551 creator A5071798264 @default.
• W4286586551 creator A5078780769 @default.
• W4286586551 creator A5084489186 @default.
• W4286586551 date "2022-07-22" @default.
• W4286586551 modified "2023-10-16" @default.
• W4286586551 title "Nanodelivery System Alters an Insect Growth Regulator’s Action Mode: From Oral Feeding to Topical Application" @default.
• W4286586551 cites W1495087981 @default.
• W4286586551 cites W1981597324 @default.
• W4286586551 cites W1982500501 @default.
• W4286586551 cites W1991752238 @default.
• W4286586551 cites W2007346245 @default.
• W4286586551 cites W2019569573 @default.
• W4286586551 cites W2038772874 @default.
• W4286586551 cites W2065065511 @default.
• W4286586551 cites W2075705506 @default.
• W4286586551 cites W2076111104 @default.
• W4286586551 cites W2091648882 @default.
• W4286586551 cites W2100083548 @default.
• W4286586551 cites W2107277218 @default.
• W4286586551 cites W2126419817 @default.
• W4286586551 cites W2127589172 @default.
• W4286586551 cites W2137662075 @default.
• W4286586551 cites W2140729960 @default.
• W4286586551 cites W2153471314 @default.
• W4286586551 cites W2154331468 @default.
• W4286586551 cites W2158564492 @default.
• W4286586551 cites W2163058976 @default.
• W4286586551 cites W2179438025 @default.
• W4286586551 cites W2218356715 @default.
• W4286586551 cites W2253382093 @default.
• W4286586551 cites W2525211581 @default.
• W4286586551 cites W2789301896 @default.
• W4286586551 cites W2793565528 @default.
• W4286586551 cites W2913973433 @default.
• W4286586551 cites W2949736804 @default.
• W4286586551 cites W2969904463 @default.
• W4286586551 cites W2974304904 @default.
• W4286586551 cites W3017157004 @default.
• W4286586551 cites W3025881278 @default.
• W4286586551 cites W3027411751 @default.
• W4286586551 cites W3027464722 @default.
• W4286586551 cites W3029369162 @default.
• W4286586551 cites W3112306057 @default.
• W4286586551 cites W3114071243 @default.
• W4286586551 cites W3118032540 @default.
• W4286586551 cites W3139240478 @default.
• W4286586551 cites W3158034981 @default.
• W4286586551 cites W3159841195 @default.
• W4286586551 cites W3184667330 @default.
• W4286586551 cites W3184915812 @default.
• W4286586551 cites W3195361821 @default.
• W4286586551 cites W4205317170 @default.
• W4286586551 cites W4220657964 @default.
• W4286586551 cites W4220902382 @default.
• W4286586551 cites W4224315073 @default.
• W4286586551 cites W4226420220 @default.
• W4286586551 doi "https://doi.org/10.1021/acsami.2c08239" @default.
• W4286586551 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35867633" @default.
• W4286586551 hasPublicationYear "2022" @default.
• W4286586551 type Work @default.
• W4286586551 citedByCount "10" @default.
• W4286586551 countsByYear W42865865512022 @default.
• W4286586551 countsByYear W42865865512023 @default.
• W4286586551 crossrefType "journal-article" @default.
• W4286586551 hasAuthorship W4286586551A5008199746 @default.
• W4286586551 hasAuthorship W4286586551A5011088053 @default.
• W4286586551 hasAuthorship W4286586551A5017277291 @default.
• W4286586551 hasAuthorship W4286586551A5018351094 @default.
• W4286586551 hasAuthorship W4286586551A5038187304 @default.
• W4286586551 hasAuthorship W4286586551A5065592637 @default.
• W4286586551 hasAuthorship W4286586551A5071798264 @default.
• W4286586551 hasAuthorship W4286586551A5078780769 @default.
• W4286586551 hasAuthorship W4286586551A5084489186 @default.
• W4286586551 hasConcept C121587506 @default.
• W4286586551 hasConcept C173758957 @default.
• W4286586551 hasConcept C178790620 @default.
• W4286586551 hasConcept C185592680 @default.
• W4286586551 hasConcept C205679159 @default.
• W4286586551 hasConcept C2777097416 @default.
• W4286586551 hasConcept C2777612826 @default.
• W4286586551 hasConcept C2777841440 @default.
• W4286586551 hasConcept C29730261 @default.
• W4286586551 hasConcept C33070731 @default.
• W4286586551 hasConcept C59822182 @default.
• W4286586551 hasConcept C86803240 @default.
• W4286586551 hasConcept C98274493 @default.
• W4286586551 hasConceptScore W4286586551C121587506 @default.
• W4286586551 hasConceptScore W4286586551C173758957 @default.
• W4286586551 hasConceptScore W4286586551C178790620 @default.
• W4286586551 hasConceptScore W4286586551C185592680 @default.

• next