Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286631347> ?p ?o ?g. }
Showing items 1 to 57 of
57
with 100 items per page.
- W4286631347 abstract "Abstract Objective : This study, aimed at using a Bayesian approach semi-competing risks technique to model the underlying predictors of early recurrence and postoperative death in patients with colorectal cancer (CRC). Methods : This study was a retrospective cohort of 284 patients with colorectal cancer who underwent surgery referred to Imam Khomeini clinic in Hamadan from 2001 to 2017. The primary outcomes were the probability of recurrence, the probability of death without recurrence, and the probability of death after recurrence. The patients 'recurrence status was determined from patients' records. The Bayesian survival modeling was carried out by semi-competing risks illness-death models in R 4.1 software Results : The results showed that gender(TR = 0.764 , 95% CI: 0.456 - 0.855), age at diagnosis (TR =0.764 , 95 % CI: 0.538 - 0.935 ), T 3 stage (TR = 0601 , 95 % CI : 0.530 - 0.713) , N 2 stage ( TR = 0.714 , 95 % CI : 0.577 - 0.935 ) , tumor size (TR = 0.709 , 95 % CI : 0.610 - 0.929), Grade (differentiation level) (TR = 0.856 , 95 % CI: 0.733 - 0.988 for poor level , TR = 0.648 , 95 % CI : 0.503 - 0.955 for moderate level) and number of chemotherapy (TR =1.583 , 95 % CI: 1.367 - 1.863) was significantly related with recurrence . Also, age at diagnosis (TR= 0.396 , 95% CI : 0.313 - 0.532) , metastasis to other sites (TR = 0.566 , 95% CI : 0.490 - 0.835) , T 3 stage (TR = 0.363 , 95 % CI : 0.592 - 0.301), T 4 stage (TR = 0.434 , 95 % CI : 0.347 - 0.545) , Grade (differentiation level) at moderate level (TR = 0.527 , 0.95 %CI : 0.387 - 0.674), tumor size (TR = 0.595 95 % CI : 0.500 - 0.679) and number of chemotherapy (TR= 1.541 , 95% CI : 1.332 - 2.243) was the significantly predicted the death. Also, age at diagnosis (TR= 0.659, 95% CI: 0.559 - 0.803) and number of chemotherapy (TR= 2.029, 95% CI: 1.792 - 2.191) was significantly related to death after recurrence. Conclusion : According to the specific results obtained for terminal and nonterminal events, appropriate screening strategies and the earlier detection of CRC leads to substantial improvements in the survival of patients." @default.
- W4286631347 created "2022-07-23" @default.
- W4286631347 creator A5002921691 @default.
- W4286631347 creator A5012878981 @default.
- W4286631347 creator A5045759988 @default.
- W4286631347 creator A5067932991 @default.
- W4286631347 date "2022-07-06" @default.
- W4286631347 modified "2023-10-16" @default.
- W4286631347 title "A Bayesian Approach to Model the Underlying Predictors of Early Recurrence and Postoperative Death in Patients with Colorectal Cancer" @default.
- W4286631347 doi "https://doi.org/10.21203/rs.3.rs-1757509/v1" @default.
- W4286631347 hasPublicationYear "2022" @default.
- W4286631347 type Work @default.
- W4286631347 citedByCount "0" @default.
- W4286631347 crossrefType "posted-content" @default.
- W4286631347 hasAuthorship W4286631347A5002921691 @default.
- W4286631347 hasAuthorship W4286631347A5012878981 @default.
- W4286631347 hasAuthorship W4286631347A5045759988 @default.
- W4286631347 hasAuthorship W4286631347A5067932991 @default.
- W4286631347 hasBestOaLocation W42866313471 @default.
- W4286631347 hasConcept C121608353 @default.
- W4286631347 hasConcept C126322002 @default.
- W4286631347 hasConcept C141071460 @default.
- W4286631347 hasConcept C143998085 @default.
- W4286631347 hasConcept C146357865 @default.
- W4286631347 hasConcept C151730666 @default.
- W4286631347 hasConcept C167135981 @default.
- W4286631347 hasConcept C2779013556 @default.
- W4286631347 hasConcept C526805850 @default.
- W4286631347 hasConcept C71924100 @default.
- W4286631347 hasConcept C86803240 @default.
- W4286631347 hasConceptScore W4286631347C121608353 @default.
- W4286631347 hasConceptScore W4286631347C126322002 @default.
- W4286631347 hasConceptScore W4286631347C141071460 @default.
- W4286631347 hasConceptScore W4286631347C143998085 @default.
- W4286631347 hasConceptScore W4286631347C146357865 @default.
- W4286631347 hasConceptScore W4286631347C151730666 @default.
- W4286631347 hasConceptScore W4286631347C167135981 @default.
- W4286631347 hasConceptScore W4286631347C2779013556 @default.
- W4286631347 hasConceptScore W4286631347C526805850 @default.
- W4286631347 hasConceptScore W4286631347C71924100 @default.
- W4286631347 hasConceptScore W4286631347C86803240 @default.
- W4286631347 hasLocation W42866313471 @default.
- W4286631347 hasOpenAccess W4286631347 @default.
- W4286631347 hasPrimaryLocation W42866313471 @default.
- W4286631347 hasRelatedWork W1484342312 @default.
- W4286631347 hasRelatedWork W1970423756 @default.
- W4286631347 hasRelatedWork W2002120878 @default.
- W4286631347 hasRelatedWork W2003938723 @default.
- W4286631347 hasRelatedWork W2047967234 @default.
- W4286631347 hasRelatedWork W2071894746 @default.
- W4286631347 hasRelatedWork W2439875401 @default.
- W4286631347 hasRelatedWork W2559850096 @default.
- W4286631347 hasRelatedWork W3013693150 @default.
- W4286631347 hasRelatedWork W3141511544 @default.
- W4286631347 isParatext "false" @default.
- W4286631347 isRetracted "false" @default.
- W4286631347 workType "article" @default.