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- W4286702011 abstract "<h3>Background</h3> Mechanical thrombectomy (MT) has become a standard treatment for patients with acute ischemic stroke due to large vessel occlusions (LVO). However, in up to 30% of the cases MT may not result in successful recanalization due to an underlying stenosis, dissection or clot recalcitrant to retrieval or aspiration. Bail out stenting has been reported to be the last treatment option to achieve permanent recanalization and a good clinical outcome. A novel approach to the ICAD treatment is the CREDO<sup>®</sup> heal Stent, a fibrin-heparin coated stent to reduce ischemic complications. <h3>Purpose</h3> To present the heal technology and report the first experience with the CREDO<sup>®</sup> heal Stent as the first coated device for ICAD treatment. <h3>Methods</h3> In vitro thrombin- antithrombin III tests were performed to measure the clotting behaviour of the coated versus the uncoated stent showing significantly reduced clotting in coated stents. Additionally, in vivo animal studies have been conducted and will be presented. Moreover, the first clinical experience using the CREDO<sup>®</sup> heal stent and the NeuroSpeed<sup>®</sup> PTA Balloon Catheter will be discussed. Stenting with CREDO<sup>®</sup> heal was performed in patients with evidence of an initial LVO and suspected underlying stenosis within a time window of <24 h after symptom onset. Results: Seventeen patients were treated from July to November 2021 with the CREDO<sup>®</sup> heal Stent. In seven cases rescue stenting has been performed and in eight cases symptomatic ICAD were treated. Overall, a final TICI ≥2b score at the end of the procedure was achieved in 82.3%. One device-related complication occurred. <h3>Conclusion</h3> The CREDO® heal stent is a promising treatment option for patients with sICAD or with persistent vascular occlusion. The final TICI sore is in accordance with uncoated devices. Its effectiveness with regard to long-term ischemic complication has to be evaluated in a prospective trial. <h3>Disclosures</h3> <b>H. Nordmeyer:</b> 2; C; Acandis." @default.
- W4286702011 created "2022-07-23" @default.
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- W4286702011 date "2022-07-01" @default.
- W4286702011 modified "2023-09-25" @default.
- W4286702011 title "P-023 Stenting of intracranial stenosis with Credo<sup>®</sup>Heal stent – early experience" @default.
- W4286702011 doi "https://doi.org/10.1136/neurintsurg-2022-snis.95" @default.
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