FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286702013> ?p ?o ?g. }

• W4286702013 abstract "<h3>Introduction</h3> Despite advancements in cardio-intervention device technology and enhanced operator experience, peri-procedure ischemic stroke remains a major and serious complication with increased mortality in patients undergoing transcatheter aortic valve replacement (TAVR). We aimed to use a novel Robotic Transcranial Doppler (NovaGuide Intelligent Ultrasound, NovaSignal Corp., Los Angeles CA USA) with Artificial Intelligence for real-time intraoperative neuromonitoring during TAVR in order to establish the safety and validity of this tool in detecting cerebral emboli and report perfusion outcomes in real-time. We also sought to highlight the critical stages of TAVR in terms of embolic disruption and differences seen between emboli count with and without cerebral protection device, overall providing preliminary data to establish a neuromonitoring tool. <h3>Methods</h3> Consecutive patients who underwent TAVR at our institution were identified and consented. Basic demographics and procedural details such as use of sentinel cerebral protection device, type of aortic valve used, and any intra- or post-procedure complications were also noted. In terms of follow-up, comprehensive neurologic examinations were performed post-procedure and at 30-days. For the purposes of identifying crucial parts of the procedure during which most catheter and guidewire activity happens, all procedures were divided into 4 stages; i-) Access to Aortic Arch, ii-) Crossing the Valve and Valvuloplasty, iii-) Valve Positioning and Implantation, and iv-) Removal of Delivery System. Total emboli HITS during the procedure as well as during individual stages were recorded. <h3>Results</h3> Twenty-five patients were prospectively enrolled in our study (mean age=80.3±7.3 years; males=15 [60%]). Cardiovascular comorbidities seen were hyperlipidemia in 20 cases (80%), followed by diabetes in 19 (76%). Coronary artery disease was seen in 16 cases (64%) as well. Five patients (20%) had a prior history of stroke or stroke mimics. Mean aortic valve area was 0.82cm² with a mean peak velocity of 3.01±1.15. Balloon assisted valvuloplasty was performed in 3 cases (12%). Cerebral sentinel protection device was used in 12 cases with the rest 13 done with embolic protection. A significantly lower emboli count was seen in cerebral protection group (470.38 vs. 693.33 <i>P=0.01</i>). Valve positioning and implantation were found to be significantly different as well (249.92 vs. 387.5 <i>P=0.01)</i> (Table 1). No stroke events were recorded immediately post-procedure and on 30-day follow-up. <h3>Conclusion</h3> In this study, we report our experience using a Robotic Transcranial Doppler (TCD) with Artificial Intelligence as a novel real-time intraoperative neuromonitoring tool in patients undergoing TAVR. By reporting quantity and distribution of high intensity transient signals (HITS) as markers of microemboli during the procedure, we report significantly lower HITS using sentinel cerebral protection. We also identify valve positioning and implantation as the most significant stage in terms of HITS during the procedure. <h3>Disclosures</h3> <b>A. Baig:</b> None. <b>C. Manion:</b> None. <b>V. Iyer:</b> None. <b>W. Khawar:</b> None. <b>B. Donnelly:</b> None. <b>A. Monteiro:</b> None. <b>E. Levy:</b> 2; C; Claret Medical, GLG Consulting, Guidepoint Global, Imperative Care, Medtronic, Rebound, StimMed;. 4; C; NeXtGen Biologics, RAPID Medical, Claret Medical, Cognition Medical, Imperative Care (formerly the Stroke Project), Rebound Therapeutics, StimMed, Three Rivers Medical;. <b>A. Siddiqui:</b> 2; C; Amnis Therapeutics, Boston Scientific, Canon Medical Systems USA Inc., Cerebrotech Medical Systems Inc., Cerenovus, Corindus Inc., Endostream Medical Ltd., Imperative Care, Inc. Integra LifeSciences C. 4; C; Adona Medical, Inc, Amnis Therapeutics, (Purchased by Boston Scientific October 2017), Blink TBI Inc., Buffalo Technology Partners Inc., Cerebrotech Medical Systems, Inc., Cognition Medical, Endostrea." @default.
• W4286702013 created "2022-07-23" @default.
• W4286702013 creator A5008553248 @default.
• W4286702013 creator A5016430037 @default.
• W4286702013 creator A5020807205 @default.
• W4286702013 creator A5047837035 @default.
• W4286702013 creator A5048382074 @default.
• W4286702013 creator A5054804638 @default.
• W4286702013 creator A5057281096 @default.
• W4286702013 creator A5073419245 @default.
• W4286702013 date "2022-07-01" @default.
• W4286702013 modified "2023-09-25" @default.
• W4286702013 title "E-142 Robotic transcranial doppler with artificial intelligence to identify cerebral emboli during transcatheter aortic valve replacement - a novel neuromonitoring tool" @default.
• W4286702013 doi "https://doi.org/10.1136/neurintsurg-2022-snis.253" @default.
• W4286702013 hasPublicationYear "2022" @default.
• W4286702013 type Work @default.
• W4286702013 citedByCount "1" @default.
• W4286702013 countsByYear W42867020132023 @default.
• W4286702013 crossrefType "proceedings-article" @default.
• W4286702013 hasAuthorship W4286702013A5008553248 @default.
• W4286702013 hasAuthorship W4286702013A5016430037 @default.
• W4286702013 hasAuthorship W4286702013A5020807205 @default.
• W4286702013 hasAuthorship W4286702013A5047837035 @default.
• W4286702013 hasAuthorship W4286702013A5048382074 @default.
• W4286702013 hasAuthorship W4286702013A5054804638 @default.
• W4286702013 hasAuthorship W4286702013A5057281096 @default.
• W4286702013 hasAuthorship W4286702013A5073419245 @default.
• W4286702013 hasBestOaLocation W42867020131 @default.
• W4286702013 hasConcept C126322002 @default.
• W4286702013 hasConcept C126838900 @default.
• W4286702013 hasConcept C127413603 @default.
• W4286702013 hasConcept C141071460 @default.
• W4286702013 hasConcept C146957229 @default.
• W4286702013 hasConcept C154281038 @default.
• W4286702013 hasConcept C164705383 @default.
• W4286702013 hasConcept C191616109 @default.
• W4286702013 hasConcept C2776570981 @default.
• W4286702013 hasConcept C2779980429 @default.
• W4286702013 hasConcept C2780007028 @default.
• W4286702013 hasConcept C2780026749 @default.
• W4286702013 hasConcept C2780645631 @default.
• W4286702013 hasConcept C2780714102 @default.
• W4286702013 hasConcept C2781285907 @default.
• W4286702013 hasConcept C71924100 @default.
• W4286702013 hasConcept C78519656 @default.
• W4286702013 hasConcept C81182388 @default.
• W4286702013 hasConceptScore W4286702013C126322002 @default.
• W4286702013 hasConceptScore W4286702013C126838900 @default.
• W4286702013 hasConceptScore W4286702013C127413603 @default.
• W4286702013 hasConceptScore W4286702013C141071460 @default.
• W4286702013 hasConceptScore W4286702013C146957229 @default.
• W4286702013 hasConceptScore W4286702013C154281038 @default.
• W4286702013 hasConceptScore W4286702013C164705383 @default.
• W4286702013 hasConceptScore W4286702013C191616109 @default.
• W4286702013 hasConceptScore W4286702013C2776570981 @default.
• W4286702013 hasConceptScore W4286702013C2779980429 @default.
• W4286702013 hasConceptScore W4286702013C2780007028 @default.
• W4286702013 hasConceptScore W4286702013C2780026749 @default.
• W4286702013 hasConceptScore W4286702013C2780645631 @default.
• W4286702013 hasConceptScore W4286702013C2780714102 @default.
• W4286702013 hasConceptScore W4286702013C2781285907 @default.
• W4286702013 hasConceptScore W4286702013C71924100 @default.
• W4286702013 hasConceptScore W4286702013C78519656 @default.
• W4286702013 hasConceptScore W4286702013C81182388 @default.
• W4286702013 hasLocation W42867020131 @default.
• W4286702013 hasOpenAccess W4286702013 @default.
• W4286702013 hasPrimaryLocation W42867020131 @default.
• W4286702013 hasRelatedWork W1594311334 @default.
• W4286702013 hasRelatedWork W2067905792 @default.
• W4286702013 hasRelatedWork W2127773604 @default.
• W4286702013 hasRelatedWork W2462155031 @default.
• W4286702013 hasRelatedWork W2804618992 @default.
• W4286702013 hasRelatedWork W2901466459 @default.
• W4286702013 hasRelatedWork W2910474408 @default.
• W4286702013 hasRelatedWork W2922536977 @default.
• W4286702013 hasRelatedWork W2944667474 @default.
• W4286702013 hasRelatedWork W4286702013 @default.
• W4286702013 isParatext "false" @default.
• W4286702013 isRetracted "false" @default.
• W4286702013 workType "article" @default.