FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286715925> ?p ?o ?g. }

• W4286715925 abstract "Abstract Introduction Cognitive impairment is common in first-episode psychosis patients and often associated with poor quality of life and functional impairment. However, most literature on this association is from high income countries and not low resource countries like Uganda. We aimed to determine the association between cognitive impairment with quality of life and functional impairment in Ugandan first-episode psychosis patients. Methods At Butabika national psychiatric hospital of Uganda, we enrolled 94 first-episode psychosis patients aged 18–60 years with a confirmed first-episode of psychosis and no previous treatment with antipsychotic medication. Neuropsychological assessment was performed using the MATRICS consensus cognitive battery (MCCB). Quality of life and functional impairment were assessed using the brief version of the World Health Organisation Quality of Life scale (WHOQOL-BREF) and the MINI International Neuropsychiatric Inventory (MINI) respectively. Linear regression analyses determined the association between impairment in different cognitive domains with various quality of life and functional impairment domains while controlling for age, gender and level of education. Results High scores in the reasoning and problem solving cognitive domain were associated with better quality of life in the psychological domain of WHOQOL-BREF ( p = 0.029). For functional impairment, high cognitive scores in the domains of speed of processing ( p = 0.018), reasoning and problem solving ( p = 0.015), working memory ( p = 0.017) and visual learning and memory ( p = 0.002) were associated with psychosis “ having a greater impact on other members of the family ” on the MINI. Higher scores in the social cognition domain were associated with “ less aggressive and disruptive behaviour ” ( p = 0.003). Conclusion Cognitive impairment in Ugandan first-episode psychotic patients is associated with both poorer quality of life and functional impairment. Remediation of cognitive function may be a plausible intervention to improve outcomes in Ugandan first-episode psychosis patients." @default.
• W4286715925 created "2022-07-23" @default.
• W4286715925 creator A5000696092 @default.
• W4286715925 creator A5001826547 @default.
• W4286715925 creator A5006179431 @default.
• W4286715925 creator A5010895502 @default.
• W4286715925 creator A5014872096 @default.
• W4286715925 creator A5042493397 @default.
• W4286715925 creator A5047234810 @default.
• W4286715925 creator A5085345633 @default.
• W4286715925 date "2022-07-23" @default.
• W4286715925 modified "2023-10-10" @default.
• W4286715925 title "The association of cognitive impairment with quality of life and functional impairment in Ugandan first-episode psychosis patients: a cross sectional study" @default.
• W4286715925 cites W1616286551 @default.
• W4286715925 cites W1654156546 @default.
• W4286715925 cites W1909358741 @default.
• W4286715925 cites W1910346860 @default.
• W4286715925 cites W1983805722 @default.
• W4286715925 cites W1984615306 @default.
• W4286715925 cites W1988580159 @default.
• W4286715925 cites W1990271377 @default.
• W4286715925 cites W1993518198 @default.
• W4286715925 cites W2001470355 @default.
• W4286715925 cites W2012563051 @default.
• W4286715925 cites W2013757355 @default.
• W4286715925 cites W2015380620 @default.
• W4286715925 cites W2016510688 @default.
• W4286715925 cites W2020041470 @default.
• W4286715925 cites W2020326582 @default.
• W4286715925 cites W2022212293 @default.
• W4286715925 cites W2029036450 @default.
• W4286715925 cites W2030496540 @default.
• W4286715925 cites W2037772308 @default.
• W4286715925 cites W2040561291 @default.
• W4286715925 cites W2045058239 @default.
• W4286715925 cites W2049413843 @default.
• W4286715925 cites W2063349274 @default.
• W4286715925 cites W2076943550 @default.
• W4286715925 cites W2097029644 @default.
• W4286715925 cites W2100018548 @default.
• W4286715925 cites W2102694811 @default.
• W4286715925 cites W2109935313 @default.
• W4286715925 cites W2111208985 @default.
• W4286715925 cites W2116431283 @default.
• W4286715925 cites W2125959313 @default.
• W4286715925 cites W2130295224 @default.
• W4286715925 cites W2139525458 @default.
• W4286715925 cites W2140606211 @default.
• W4286715925 cites W2146711795 @default.
• W4286715925 cites W2165955750 @default.
• W4286715925 cites W2170663130 @default.
• W4286715925 cites W2202313463 @default.
• W4286715925 cites W2217799529 @default.
• W4286715925 cites W2286562311 @default.
• W4286715925 cites W2312830359 @default.
• W4286715925 cites W2527824850 @default.
• W4286715925 cites W2600660804 @default.
• W4286715925 cites W2618150309 @default.
• W4286715925 cites W2788717113 @default.
• W4286715925 cites W2790707306 @default.
• W4286715925 cites W2791294818 @default.
• W4286715925 cites W2791904031 @default.
• W4286715925 cites W2794134976 @default.
• W4286715925 cites W2796215501 @default.
• W4286715925 cites W2910258489 @default.
• W4286715925 cites W2912103210 @default.
• W4286715925 cites W2913031894 @default.
• W4286715925 cites W2981609139 @default.
• W4286715925 cites W2982444451 @default.
• W4286715925 cites W2997255143 @default.
• W4286715925 cites W2999488690 @default.
• W4286715925 cites W3004062019 @default.
• W4286715925 cites W3006611971 @default.
• W4286715925 cites W3007146357 @default.
• W4286715925 cites W3019591675 @default.
• W4286715925 cites W3024074306 @default.
• W4286715925 cites W3026587367 @default.
• W4286715925 cites W3034083181 @default.
• W4286715925 cites W3172202196 @default.
• W4286715925 cites W4200219875 @default.
• W4286715925 cites W4233725888 @default.
• W4286715925 cites W562866358 @default.
• W4286715925 cites W1502051113 @default.
• W4286715925 doi "https://doi.org/10.1186/s12955-022-02020-x" @default.
• W4286715925 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35870969" @default.
• W4286715925 hasPublicationYear "2022" @default.
• W4286715925 type Work @default.
• W4286715925 citedByCount "1" @default.
• W4286715925 countsByYear W42867159252023 @default.
• W4286715925 crossrefType "journal-article" @default.
• W4286715925 hasAuthorship W4286715925A5000696092 @default.
• W4286715925 hasAuthorship W4286715925A5001826547 @default.
• W4286715925 hasAuthorship W4286715925A5006179431 @default.
• W4286715925 hasAuthorship W4286715925A5010895502 @default.
• W4286715925 hasAuthorship W4286715925A5014872096 @default.
• W4286715925 hasAuthorship W4286715925A5042493397 @default.
• W4286715925 hasAuthorship W4286715925A5047234810 @default.
• W4286715925 hasAuthorship W4286715925A5085345633 @default.
• W4286715925 hasBestOaLocation W42867159251 @default.
• W4286715925 hasConcept C118552586 @default.

• next