Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286853772> ?p ?o ?g. }
Showing items 1 to 66 of
66
with 100 items per page.
- W4286853772 abstract "Bone marrow-derived macrophages (BMDMs) are mature leukocytes that serve a critical physiological role as professional phagocytes capable of clearing a variety of particles. Normally, BMDMs are restricted from the central nervous system (CNS), but following an injury, they can readily infiltrate. Once within the injured CNS tissue, BMDMs are the primary cell type responsible for the clearance of injury-derived cellular debris, including large quantities of lipid rich myelin debris. The neuropathological ramifications of BMDM infiltration and myelin debris phagocytosis within the CNS are complex and not well understood. The protocols described here, allow for the direct in vitro study of BMDMs in the context of CNS injury. We cover murine BMDM isolation and culture, myelin debris preparation, and assays to assess BMDM myelin debris phagocytosis. These techniques produce robust quantifiable results without the need for significant specialized equipment or materials, yet can be easily customized to meet the needs of researchers." @default.
- W4286853772 created "2022-07-25" @default.
- W4286853772 creator A5015283451 @default.
- W4286853772 creator A5026813618 @default.
- W4286853772 creator A5065423394 @default.
- W4286853772 creator A5082170009 @default.
- W4286853772 date "2017-12-30" @default.
- W4286853772 modified "2023-10-03" @default.
- W4286853772 title "<em>In Vitro </em>Phagocytosis of Myelin Debris by Bone Marrow-Derived Macrophages" @default.
- W4286853772 doi "https://doi.org/10.3791/56322-v" @default.
- W4286853772 hasPublicationYear "2017" @default.
- W4286853772 type Work @default.
- W4286853772 citedByCount "2" @default.
- W4286853772 countsByYear W42868537722023 @default.
- W4286853772 crossrefType "journal-article" @default.
- W4286853772 hasAuthorship W4286853772A5015283451 @default.
- W4286853772 hasAuthorship W4286853772A5026813618 @default.
- W4286853772 hasAuthorship W4286853772A5065423394 @default.
- W4286853772 hasAuthorship W4286853772A5082170009 @default.
- W4286853772 hasConcept C151730666 @default.
- W4286853772 hasConcept C160448771 @default.
- W4286853772 hasConcept C169760540 @default.
- W4286853772 hasConcept C185592680 @default.
- W4286853772 hasConcept C202751555 @default.
- W4286853772 hasConcept C203014093 @default.
- W4286853772 hasConcept C2776914184 @default.
- W4286853772 hasConcept C2778609137 @default.
- W4286853772 hasConcept C2779343474 @default.
- W4286853772 hasConcept C2779830541 @default.
- W4286853772 hasConcept C2780007613 @default.
- W4286853772 hasConcept C529278444 @default.
- W4286853772 hasConcept C55493867 @default.
- W4286853772 hasConcept C86803240 @default.
- W4286853772 hasConcept C95444343 @default.
- W4286853772 hasConceptScore W4286853772C151730666 @default.
- W4286853772 hasConceptScore W4286853772C160448771 @default.
- W4286853772 hasConceptScore W4286853772C169760540 @default.
- W4286853772 hasConceptScore W4286853772C185592680 @default.
- W4286853772 hasConceptScore W4286853772C202751555 @default.
- W4286853772 hasConceptScore W4286853772C203014093 @default.
- W4286853772 hasConceptScore W4286853772C2776914184 @default.
- W4286853772 hasConceptScore W4286853772C2778609137 @default.
- W4286853772 hasConceptScore W4286853772C2779343474 @default.
- W4286853772 hasConceptScore W4286853772C2779830541 @default.
- W4286853772 hasConceptScore W4286853772C2780007613 @default.
- W4286853772 hasConceptScore W4286853772C529278444 @default.
- W4286853772 hasConceptScore W4286853772C55493867 @default.
- W4286853772 hasConceptScore W4286853772C86803240 @default.
- W4286853772 hasConceptScore W4286853772C95444343 @default.
- W4286853772 hasIssue "130" @default.
- W4286853772 hasLocation W42868537721 @default.
- W4286853772 hasOpenAccess W4286853772 @default.
- W4286853772 hasPrimaryLocation W42868537721 @default.
- W4286853772 hasRelatedWork W1997795701 @default.
- W4286853772 hasRelatedWork W2001748009 @default.
- W4286853772 hasRelatedWork W2038039322 @default.
- W4286853772 hasRelatedWork W2041785681 @default.
- W4286853772 hasRelatedWork W2083331927 @default.
- W4286853772 hasRelatedWork W2109315419 @default.
- W4286853772 hasRelatedWork W2391855221 @default.
- W4286853772 hasRelatedWork W2807736597 @default.
- W4286853772 hasRelatedWork W3134467461 @default.
- W4286853772 hasRelatedWork W4210299272 @default.
- W4286853772 isParatext "false" @default.
- W4286853772 isRetracted "false" @default.
- W4286853772 workType "article" @default.