Matches in SemOpenAlex for { <https://semopenalex.org/work/W4286855743> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4286855743 abstract "Cardiovascular disease caused by atherosclerosis is the leading cause of death in the developed world. Narrowing of the vessel lumen, due to atherosclerotic plaque development or the rupturing of established plaques, interrupts normal blood flow leading to various morbidities such as myocardial infarction and stroke. In the clinic endovascular procedures such as angioplasty are commonly performed to reopen the lumen. However, these treatments inevitably damage the vessel wall as well as the vascular endothelium, triggering an excessive healing response and the development of a neointimal plaque that extends into the lumen causing vessel restenosis (re-narrowing). Restenosis remains a major cause of failure of endovascular treatments for atherosclerosis. Thus, preclinical animal models of restenosis are vitally important for investigating the pathophysiological mechanisms as well as translational approaches to vascular interventions. Among several murine experimental models, femoral artery wire injury is widely accepted as the most suitable for studies of post-angioplasty restenosis because it closely resembles the angioplasty procedure that injures both endothelium and vessel wall. However, many researchers have difficulty utilizing this model due to its high degree of technical difficulty. This is primarily because a metal wire needs to be inserted into the femoral artery, which is approximately three times thinner than the wire, to generate sufficient injury to induce prominent neointima. Here, we describe the essential surgical details to effectively overcome the major technical difficulties of this model. By following the presented procedures, performing the mouse femoral artery wire injury becomes easier. Once familiarized, the whole procedure can be completed within 20 min." @default.
- W4286855743 created "2022-07-25" @default.
- W4286855743 creator A5015204240 @default.
- W4286855743 creator A5030510460 @default.
- W4286855743 creator A5040070831 @default.
- W4286855743 creator A5040778839 @default.
- W4286855743 creator A5042606066 @default.
- W4286855743 creator A5042623407 @default.
- W4286855743 creator A5048396052 @default.
- W4286855743 creator A5054811990 @default.
- W4286855743 creator A5058659834 @default.
- W4286855743 creator A5079377941 @default.
- W4286855743 date "2015-03-10" @default.
- W4286855743 modified "2023-09-25" @default.
- W4286855743 title "A Murine Model of Arterial Restenosis: Technical Aspects of Femoral Wire Injury" @default.
- W4286855743 doi "https://doi.org/10.3791/52561-v" @default.
- W4286855743 hasPublicationYear "2015" @default.
- W4286855743 type Work @default.
- W4286855743 citedByCount "0" @default.
- W4286855743 crossrefType "journal-article" @default.
- W4286855743 hasAuthorship W4286855743A5015204240 @default.
- W4286855743 hasAuthorship W4286855743A5030510460 @default.
- W4286855743 hasAuthorship W4286855743A5040070831 @default.
- W4286855743 hasAuthorship W4286855743A5040778839 @default.
- W4286855743 hasAuthorship W4286855743A5042606066 @default.
- W4286855743 hasAuthorship W4286855743A5042623407 @default.
- W4286855743 hasAuthorship W4286855743A5048396052 @default.
- W4286855743 hasAuthorship W4286855743A5054811990 @default.
- W4286855743 hasAuthorship W4286855743A5058659834 @default.
- W4286855743 hasAuthorship W4286855743A5079377941 @default.
- W4286855743 hasBestOaLocation W42868557432 @default.
- W4286855743 hasConcept C126322002 @default.
- W4286855743 hasConcept C126838900 @default.
- W4286855743 hasConcept C131631996 @default.
- W4286855743 hasConcept C164705383 @default.
- W4286855743 hasConcept C2776992346 @default.
- W4286855743 hasConcept C2777339539 @default.
- W4286855743 hasConcept C2778095995 @default.
- W4286855743 hasConcept C2778213512 @default.
- W4286855743 hasConcept C2778283817 @default.
- W4286855743 hasConcept C2778583881 @default.
- W4286855743 hasConcept C2779723990 @default.
- W4286855743 hasConcept C2780326628 @default.
- W4286855743 hasConcept C500558357 @default.
- W4286855743 hasConcept C71924100 @default.
- W4286855743 hasConceptScore W4286855743C126322002 @default.
- W4286855743 hasConceptScore W4286855743C126838900 @default.
- W4286855743 hasConceptScore W4286855743C131631996 @default.
- W4286855743 hasConceptScore W4286855743C164705383 @default.
- W4286855743 hasConceptScore W4286855743C2776992346 @default.
- W4286855743 hasConceptScore W4286855743C2777339539 @default.
- W4286855743 hasConceptScore W4286855743C2778095995 @default.
- W4286855743 hasConceptScore W4286855743C2778213512 @default.
- W4286855743 hasConceptScore W4286855743C2778283817 @default.
- W4286855743 hasConceptScore W4286855743C2778583881 @default.
- W4286855743 hasConceptScore W4286855743C2779723990 @default.
- W4286855743 hasConceptScore W4286855743C2780326628 @default.
- W4286855743 hasConceptScore W4286855743C500558357 @default.
- W4286855743 hasConceptScore W4286855743C71924100 @default.
- W4286855743 hasIssue "97" @default.
- W4286855743 hasLocation W42868557431 @default.
- W4286855743 hasLocation W42868557432 @default.
- W4286855743 hasOpenAccess W4286855743 @default.
- W4286855743 hasPrimaryLocation W42868557431 @default.
- W4286855743 hasRelatedWork W1978659035 @default.
- W4286855743 hasRelatedWork W2001297089 @default.
- W4286855743 hasRelatedWork W2004033129 @default.
- W4286855743 hasRelatedWork W2006542102 @default.
- W4286855743 hasRelatedWork W2093315647 @default.
- W4286855743 hasRelatedWork W2147247409 @default.
- W4286855743 hasRelatedWork W2379694518 @default.
- W4286855743 hasRelatedWork W2405535768 @default.
- W4286855743 hasRelatedWork W2413586273 @default.
- W4286855743 hasRelatedWork W2418304447 @default.
- W4286855743 isParatext "false" @default.
- W4286855743 isRetracted "false" @default.
- W4286855743 workType "article" @default.