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- W4287029885 abstract "In this work, we propose to catch the complexity of the membrane potential's dynamic of a motoneuron between its spikes, taking into account the spikes from other neurons around. Our approach relies on two types of data: extracellular recordings of multiple spikes trains and intracellular recordings of the membrane potential of a central neuron. Our main contribution is to provide a unified framework and a complete pipeline to analyze neuronal activity from data extraction to statistical inference. The first step of the procedure is to select a subnetwork of neurons impacting the central neuron: we use a multivariate Hawkes process to model the spike trains of all neurons and compare two sparse inference procedures to identify the connectivity graph. Then we infer a jump-diffusion dynamic in which jumps are driven from a Hawkes process, the occurrences of which correspond to the spike trains of the aforementioned subset of neurons that interact with the central neuron. We validate the Hawkes model with a goodness-of-fit test and we show that taking into account the information from the connectivity graph improves the inference of the jump-diffusion process. The entire code has been developed and is freely available on GitHub." @default.
- W4287029885 created "2022-07-25" @default.
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- W4287029885 date "2022-04-15" @default.
- W4287029885 modified "2023-09-30" @default.
- W4287029885 title "Neuronal Network Inference and Membrane Potential Model using Multivariate Hawkes Processes" @default.
- W4287029885 hasPublicationYear "2022" @default.
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