Matches in SemOpenAlex for { <https://semopenalex.org/work/W4287185324> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W4287185324 abstract "Nitric Oxide (NO) is administered as gas for inhalation to induce selective pulmonary vasodilation. It is a safe therapy, with few potential risks even if administered at high concentration. Inhaled NO gas is routinely used to increase systemic oxygenation in different disease conditions. The administration of high concentrations of NO also exerts a virucidal effect in vitro. Owing to its favorable pharmacodynamic and safety profiles, the familiarity in its use by critical care providers, and the potential for a direct virucidal effect, NO is clinically used in patients with coronavirus disease-2019 (COVID-19). Nevertheless, no device is currently available to easily administer inhaled NO at concentrations higher than 80 parts per million (ppm) at various inspired oxygen fractions, without the need for dedicated, heavy, and costly equipment. The development of a reliable, safe, inexpensive, lightweight, and ventilator-free solution is crucial, particularly for the early treatment of non-intubated patients outside of the intensive care unit (ICU) and in a limited-resource scenario. To overcome such a barrier, a simple system for the non-invasive NO gas administration up to 250 ppm was developed using standard consumables and a scavenging chamber. The method has been proven safe and reliable in delivering a specified NO concentration while limiting nitrogen dioxide levels. This paper aims to provide clinicians and researchers with the necessary information on how to assemble or adapt such a system for research purposes or clinical use in COVID-19 or other diseases in which NO administration might be beneficial." @default.
- W4287185324 created "2022-07-25" @default.
- W4287185324 creator A5002870553 @default.
- W4287185324 creator A5006562205 @default.
- W4287185324 creator A5011197386 @default.
- W4287185324 creator A5013534438 @default.
- W4287185324 creator A5039568998 @default.
- W4287185324 creator A5040470692 @default.
- W4287185324 creator A5050160783 @default.
- W4287185324 creator A5060338002 @default.
- W4287185324 creator A5073059702 @default.
- W4287185324 creator A5079746187 @default.
- W4287185324 creator A5083017627 @default.
- W4287185324 date "2021-05-04" @default.
- W4287185324 modified "2023-09-28" @default.
- W4287185324 title "A Novel Inhalation Mask System to Deliver High Concentrations of Nitric Oxide Gas in Spontaneously Breathing Subjects" @default.
- W4287185324 doi "https://doi.org/10.3791/61769-v" @default.
- W4287185324 hasPublicationYear "2021" @default.
- W4287185324 type Work @default.
- W4287185324 citedByCount "0" @default.
- W4287185324 crossrefType "journal-article" @default.
- W4287185324 hasAuthorship W4287185324A5002870553 @default.
- W4287185324 hasAuthorship W4287185324A5006562205 @default.
- W4287185324 hasAuthorship W4287185324A5011197386 @default.
- W4287185324 hasAuthorship W4287185324A5013534438 @default.
- W4287185324 hasAuthorship W4287185324A5039568998 @default.
- W4287185324 hasAuthorship W4287185324A5040470692 @default.
- W4287185324 hasAuthorship W4287185324A5050160783 @default.
- W4287185324 hasAuthorship W4287185324A5060338002 @default.
- W4287185324 hasAuthorship W4287185324A5073059702 @default.
- W4287185324 hasAuthorship W4287185324A5079746187 @default.
- W4287185324 hasAuthorship W4287185324A5083017627 @default.
- W4287185324 hasConcept C126322002 @default.
- W4287185324 hasConcept C142724271 @default.
- W4287185324 hasConcept C147789679 @default.
- W4287185324 hasConcept C177713679 @default.
- W4287185324 hasConcept C185592680 @default.
- W4287185324 hasConcept C2776954882 @default.
- W4287185324 hasConcept C2779134260 @default.
- W4287185324 hasConcept C3008058167 @default.
- W4287185324 hasConcept C42219234 @default.
- W4287185324 hasConcept C519581460 @default.
- W4287185324 hasConcept C524204448 @default.
- W4287185324 hasConcept C62126406 @default.
- W4287185324 hasConcept C70289976 @default.
- W4287185324 hasConcept C71924100 @default.
- W4287185324 hasConceptScore W4287185324C126322002 @default.
- W4287185324 hasConceptScore W4287185324C142724271 @default.
- W4287185324 hasConceptScore W4287185324C147789679 @default.
- W4287185324 hasConceptScore W4287185324C177713679 @default.
- W4287185324 hasConceptScore W4287185324C185592680 @default.
- W4287185324 hasConceptScore W4287185324C2776954882 @default.
- W4287185324 hasConceptScore W4287185324C2779134260 @default.
- W4287185324 hasConceptScore W4287185324C3008058167 @default.
- W4287185324 hasConceptScore W4287185324C42219234 @default.
- W4287185324 hasConceptScore W4287185324C519581460 @default.
- W4287185324 hasConceptScore W4287185324C524204448 @default.
- W4287185324 hasConceptScore W4287185324C62126406 @default.
- W4287185324 hasConceptScore W4287185324C70289976 @default.
- W4287185324 hasConceptScore W4287185324C71924100 @default.
- W4287185324 hasIssue "171" @default.
- W4287185324 hasLocation W42871853241 @default.
- W4287185324 hasOpenAccess W4287185324 @default.
- W4287185324 hasPrimaryLocation W42871853241 @default.
- W4287185324 hasRelatedWork W2022670677 @default.
- W4287185324 hasRelatedWork W2024420807 @default.
- W4287185324 hasRelatedWork W2171701978 @default.
- W4287185324 hasRelatedWork W2318526809 @default.
- W4287185324 hasRelatedWork W2337423144 @default.
- W4287185324 hasRelatedWork W2359039736 @default.
- W4287185324 hasRelatedWork W2395334936 @default.
- W4287185324 hasRelatedWork W2404089580 @default.
- W4287185324 hasRelatedWork W2469966616 @default.
- W4287185324 hasRelatedWork W3006076840 @default.
- W4287185324 isParatext "false" @default.
- W4287185324 isRetracted "false" @default.
- W4287185324 workType "article" @default.