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• W4287218110 abstract "Care for People with Multiple Sclerosis (PwMS) is increasingly complex, requiring innovations in care. Canada has high rates of MS; it is challenging for general neurologists to optimally care for PwMS with busy office practices. The aim of this study was to evaluate the effects of add-on Nurse Practitioner (NP)-led care for PwMS on depression and anxiety (Hospital Anxiety and Depression Scale, HADS), compared to usual care (community neurologist, family physician).PwMS followed by community neurologists were randomized to add-on NP-led or Usual care for 6 months. Primary outcome was the change in HADS at 3 months. Secondary outcomes were HADS (6 months), EQ5D, MSIF, CAREQOL-MS, at 3 and 6 months, and Consultant Satisfaction Survey (6 months).We recruited 248 participants; 228 completed the trial (NP-led care arm n = 120, Usual care arm n = 108). There were no significant baseline differences between groups. Study subjects were highly educated (71.05%), working full-time (41.23%), living independently (68.86%), with mean age of 47.32 (11.09), mean EDSS 2.53 (SD 2.06), mean duration since MS diagnosis 12.18 years (SD 8.82) and 85% had relapsing remitting MS. Mean change in HADS depression (3 months) was: -0.41 (SD 2.81) NP-led care group vs 1.11 (2.98) Usual care group p = 0.001, sustained at 6 months; for anxiety, - 0.32 (2.73) NP-led care group vs 0.42 (2.82) Usual care group, p = 0.059. Other secondary outcomes were not significantly different. There was no difference in satisfaction of care in the NP-led care arm (63.83 (5.63)) vs Usual care (62.82 (5.45)), p = 0.194).Add-on NP-led care improved depression compared to usual neurologist care and 3 and 6 months in PwMS, and there was no difference in satisfaction with care. Further research is needed to explore how NPs could enrich care provided for PwMS in healthcare settings.Retrospectively registered on clinicaltrials.gov ( ClinicalTrials.gov Identifier: NCT04388592 , 14/05/2020)." @default.
• W4287218110 created "2022-07-25" @default.
• W4287218110 creator A5001735285 @default.
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• W4287218110 date "2022-07-25" @default.
• W4287218110 modified "2023-10-18" @default.
• W4287218110 title "The effect of nurse practitioner (NP-led) care on health-related quality of life in people with multiple sclerosis – a randomized trial" @default.
• W4287218110 cites W155259919 @default.
• W4287218110 cites W1599399885 @default.
• W4287218110 cites W1625639159 @default.
• W4287218110 cites W1968709132 @default.
• W4287218110 cites W1977040272 @default.
• W4287218110 cites W1978606919 @default.
• W4287218110 cites W1980633803 @default.
• W4287218110 cites W1983841278 @default.
• W4287218110 cites W1992369461 @default.
• W4287218110 cites W1997876682 @default.
• W4287218110 cites W1998137645 @default.
• W4287218110 cites W2001781527 @default.
• W4287218110 cites W2019635841 @default.
• W4287218110 cites W2024480021 @default.
• W4287218110 cites W2024696873 @default.
• W4287218110 cites W2025556060 @default.
• W4287218110 cites W2027285375 @default.
• W4287218110 cites W2036853725 @default.
• W4287218110 cites W2041346149 @default.
• W4287218110 cites W2045251418 @default.
• W4287218110 cites W2050053292 @default.
• W4287218110 cites W2051933367 @default.
• W4287218110 cites W2053568407 @default.
• W4287218110 cites W2054922959 @default.
• W4287218110 cites W2054971592 @default.
• W4287218110 cites W2060545199 @default.
• W4287218110 cites W2061375983 @default.
• W4287218110 cites W2064467071 @default.
• W4287218110 cites W2082346376 @default.
• W4287218110 cites W2084831078 @default.
• W4287218110 cites W2095338052 @default.
• W4287218110 cites W2100116912 @default.
• W4287218110 cites W2105242813 @default.
• W4287218110 cites W2105913548 @default.
• W4287218110 cites W2108230902 @default.
• W4287218110 cites W2111272873 @default.
• W4287218110 cites W2114728329 @default.
• W4287218110 cites W2121848908 @default.
• W4287218110 cites W2122545833 @default.
• W4287218110 cites W2128868698 @default.
• W4287218110 cites W2132906244 @default.
• W4287218110 cites W2134894009 @default.
• W4287218110 cites W2135865063 @default.
• W4287218110 cites W2142577589 @default.
• W4287218110 cites W2157066588 @default.
• W4287218110 cites W2159097022 @default.
• W4287218110 cites W2160706442 @default.
• W4287218110 cites W2164073488 @default.
• W4287218110 cites W2165672252 @default.
• W4287218110 cites W2167082840 @default.
• W4287218110 cites W2170173133 @default.
• W4287218110 cites W2178687657 @default.
• W4287218110 cites W2184060246 @default.
• W4287218110 cites W2198777597 @default.
• W4287218110 cites W2238427603 @default.
• W4287218110 cites W2240081821 @default.
• W4287218110 cites W2256560155 @default.
• W4287218110 cites W2463810424 @default.
• W4287218110 cites W2518138609 @default.
• W4287218110 cites W2558115423 @default.
• W4287218110 cites W2616725533 @default.
• W4287218110 cites W2726625509 @default.
• W4287218110 cites W2742938936 @default.
• W4287218110 cites W2763518143 @default.
• W4287218110 cites W2763587045 @default.
• W4287218110 cites W2768662349 @default.
• W4287218110 cites W2770280018 @default.
• W4287218110 cites W2787204655 @default.
• W4287218110 cites W2793736701 @default.
• W4287218110 cites W2805652711 @default.
• W4287218110 cites W2890641484 @default.
• W4287218110 cites W2896294018 @default.
• W4287218110 cites W2896455370 @default.
• W4287218110 cites W2899172313 @default.
• W4287218110 cites W2917345120 @default.
• W4287218110 cites W2984524403 @default.
• W4287218110 cites W2989474435 @default.
• W4287218110 cites W2990934287 @default.
• W4287218110 cites W2998869585 @default.
• W4287218110 cites W3024573054 @default.
• W4287218110 cites W3044866728 @default.
• W4287218110 cites W3099273656 @default.
• W4287218110 cites W3131359730 @default.
• W4287218110 cites W3161941991 @default.
• W4287218110 cites W3180459776 @default.
• W4287218110 cites W4235441840 @default.
• W4287218110 doi "https://doi.org/10.1186/s12883-022-02809-9" @default.
• W4287218110 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35879701" @default.
• W4287218110 hasPublicationYear "2022" @default.
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