FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4287318531> ?p ?o ?g. }

• W4287318531 endingPage "710" @default.
• W4287318531 startingPage "699" @default.
• W4287318531 abstract "Triple layered tablet having various excipients and a new combination of APIs i.e. amlodipine besylate, rosuvastatin calcium and hydrochlorothiazide was prepared through wet granulation. The concentration of disintegrant and diluent was kept different in formulations of all APIs. At compression stage, nine different formulations from H1 to H9 having different combinations were prepared. Layers T1, T2 and T3 of all the three APIs had disintegrant concentration of 3%, 5% and 7 % respectively. In vitro analysis of granules was made by determining angle of repose, loss on drying, bulk density, tapped density, hausner ratio. Results of all these parameters were quite similar in all layers, which showed that change in disintegrant concentration does not affect the flow ability of granules to much extent. After compression, tablets were further subjected to weight variation, hardness, thickness, friability, disintegration, dissolution studies and FTIR. In vitro drug release data of all formulations were studied which showed that all the formulations exhibited zero order release. Results indicated that H8 had the best results in terms of physicochemical properties, assay and dissolution studies. The external morphology of formulations were further analyzed using scanning electron microscopy and differential scanning calorimetry. Triple layered tablet was successfully developed and characterized." @default.
• W4287318531 created "2022-07-25" @default.
• W4287318531 creator A5001310433 @default.
• W4287318531 creator A5019644708 @default.
• W4287318531 creator A5020226076 @default.
• W4287318531 creator A5029952551 @default.
• W4287318531 creator A5031004810 @default.
• W4287318531 creator A5052404930 @default.
• W4287318531 creator A5059417205 @default.
• W4287318531 creator A5073592697 @default.
• W4287318531 creator A5079415117 @default.
• W4287318531 date "2021-03-01" @default.
• W4287318531 modified "2023-10-03" @default.
• W4287318531 title "Formulation development and in vitro characterization of triple layer tablet containing amlodipine besylate, rosuvastatin calcium and hydrochlorothiazide." @default.
• W4287318531 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34275805" @default.
• W4287318531 hasPublicationYear "2021" @default.
• W4287318531 type Work @default.
• W4287318531 citedByCount "0" @default.
• W4287318531 crossrefType "journal-article" @default.
• W4287318531 hasAuthorship W4287318531A5001310433 @default.
• W4287318531 hasAuthorship W4287318531A5019644708 @default.
• W4287318531 hasAuthorship W4287318531A5020226076 @default.
• W4287318531 hasAuthorship W4287318531A5029952551 @default.
• W4287318531 hasAuthorship W4287318531A5031004810 @default.
• W4287318531 hasAuthorship W4287318531A5052404930 @default.
• W4287318531 hasAuthorship W4287318531A5059417205 @default.
• W4287318531 hasAuthorship W4287318531A5073592697 @default.
• W4287318531 hasAuthorship W4287318531A5079415117 @default.
• W4287318531 hasConcept C121332964 @default.
• W4287318531 hasConcept C126838900 @default.
• W4287318531 hasConcept C127413603 @default.
• W4287318531 hasConcept C13965031 @default.
• W4287318531 hasConcept C151995515 @default.
• W4287318531 hasConcept C159985019 @default.
• W4287318531 hasConcept C175804951 @default.
• W4287318531 hasConcept C178790620 @default.
• W4287318531 hasConcept C185592680 @default.
• W4287318531 hasConcept C191168616 @default.
• W4287318531 hasConcept C192562407 @default.
• W4287318531 hasConcept C26771246 @default.
• W4287318531 hasConcept C2776035855 @default.
• W4287318531 hasConcept C2779646130 @default.
• W4287318531 hasConcept C2780361556 @default.
• W4287318531 hasConcept C2780499067 @default.
• W4287318531 hasConcept C2908737378 @default.
• W4287318531 hasConcept C39519442 @default.
• W4287318531 hasConcept C42360764 @default.
• W4287318531 hasConcept C43617362 @default.
• W4287318531 hasConcept C521977710 @default.
• W4287318531 hasConcept C71924100 @default.
• W4287318531 hasConcept C84393581 @default.
• W4287318531 hasConcept C88380143 @default.
• W4287318531 hasConcept C88463166 @default.
• W4287318531 hasConcept C97355855 @default.
• W4287318531 hasConcept C98274493 @default.
• W4287318531 hasConceptScore W4287318531C121332964 @default.
• W4287318531 hasConceptScore W4287318531C126838900 @default.
• W4287318531 hasConceptScore W4287318531C127413603 @default.
• W4287318531 hasConceptScore W4287318531C13965031 @default.
• W4287318531 hasConceptScore W4287318531C151995515 @default.
• W4287318531 hasConceptScore W4287318531C159985019 @default.
• W4287318531 hasConceptScore W4287318531C175804951 @default.
• W4287318531 hasConceptScore W4287318531C178790620 @default.
• W4287318531 hasConceptScore W4287318531C185592680 @default.
• W4287318531 hasConceptScore W4287318531C191168616 @default.
• W4287318531 hasConceptScore W4287318531C192562407 @default.
• W4287318531 hasConceptScore W4287318531C26771246 @default.
• W4287318531 hasConceptScore W4287318531C2776035855 @default.
• W4287318531 hasConceptScore W4287318531C2779646130 @default.
• W4287318531 hasConceptScore W4287318531C2780361556 @default.
• W4287318531 hasConceptScore W4287318531C2780499067 @default.
• W4287318531 hasConceptScore W4287318531C2908737378 @default.
• W4287318531 hasConceptScore W4287318531C39519442 @default.
• W4287318531 hasConceptScore W4287318531C42360764 @default.
• W4287318531 hasConceptScore W4287318531C43617362 @default.
• W4287318531 hasConceptScore W4287318531C521977710 @default.
• W4287318531 hasConceptScore W4287318531C71924100 @default.
• W4287318531 hasConceptScore W4287318531C84393581 @default.
• W4287318531 hasConceptScore W4287318531C88380143 @default.
• W4287318531 hasConceptScore W4287318531C88463166 @default.
• W4287318531 hasConceptScore W4287318531C97355855 @default.
• W4287318531 hasConceptScore W4287318531C98274493 @default.
• W4287318531 hasIssue "2(Supplementary)" @default.
• W4287318531 hasLocation W42873185311 @default.
• W4287318531 hasOpenAccess W4287318531 @default.
• W4287318531 hasPrimaryLocation W42873185311 @default.
• W4287318531 hasRelatedWork W10160321 @default.
• W4287318531 hasRelatedWork W10750264 @default.
• W4287318531 hasRelatedWork W15840329 @default.
• W4287318531 hasRelatedWork W21345603 @default.
• W4287318531 hasRelatedWork W24288037 @default.
• W4287318531 hasRelatedWork W423493 @default.
• W4287318531 hasRelatedWork W7877370 @default.
• W4287318531 hasRelatedWork W8496227 @default.
• W4287318531 hasRelatedWork W8880792 @default.
• W4287318531 hasRelatedWork W8810879 @default.
• W4287318531 hasVolume "34" @default.
• W4287318531 isParatext "false" @default.

• next