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- W4287489724 abstract "Craniofacial deformities involve soft tissue and skeletal abnormalities. Facial bone growth is based on congenital defects and iatrogenic factors, in which muscle activity is important. Understanding the effects of muscle function on facial bone growth may help us in clinical treatment. Although there have been some studies, fewer have focused on the effects of perioral muscle continuity on maxillary development, which needs further research. In our study, mimic perioral muscle surgeries were performed in twenty 3-day Wistar rats, which were divided into four equal groups, including five untreated rats as control (Ctrl), five rats by unilateral perioral muscle incision (MI), five rats by unilateral perioral muscle incision combined with muscle stripping (MIMS) and five rats treated by unilateral perioral muscle incision combined with periosteal stripping (MIPS). After six weeks, skulls were imaged and measured by micro-CT scan and hematoxylin-eosin staining. Differences in the rats' premaxilla were analyzed with self-contrasted and group-control studies. Compared with Ctrl group, there were significant premaxillary developmental defects in the affected side of the rats in all three surgical groups. In the affected side, both the width and the length of the premaxilla were less than the unaffected side, particularly in MIMS and MIPS groups. Group-control study showed that the ratio of premaxillary length of affected side to unaffected side had significant differences between MI and MIMS. The conclusion was that complete perioral muscle continuity with intact muscle attachment on the premaxilla is the driving force for the premaxillary development." @default.
- W4287489724 created "2022-07-25" @default.
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- W4287489724 date "2021-01-01" @default.
- W4287489724 modified "2023-09-30" @default.
- W4287489724 title "The perioral muscle continuum affects premaxillary development in Wistar rats." @default.
- W4287489724 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34956458" @default.
- W4287489724 hasPublicationYear "2021" @default.
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