FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4287578625> ?p ?o ?g. }

• W4287578625 endingPage "1201" @default.
• W4287578625 startingPage "1194" @default.
• W4287578625 abstract "To describe the clinical and paraclinical findings, treatment options and long-term outcomes in autoimmune encephalitis (AE), with a close look to epilepsy.In this retrospective observational cohort study, we enrolled patients with new-onset seizures in the context of AE. We compared clinical and paraclinical findings in patients with and without evidence of antibodies.Overall, 263 patients (138 females; median age 55 years, range 4-86) were followed up for a median time of 30 months (range 12-120). Antineuronal antibodies were detected in 63.50%.Antibody-positive patients had multiple seizure types (p=0.01) and prevalent involvement of temporal regions (p=0.02). A higher prevalence of episodes of SE was found in the antibody-negative group (p<0.001).Immunotherapy was prescribed in 88.60%, and effective in 61.80%. Independent predictors of favourable outcome of the AE were early immunotherapy (p<0.001) and the detection of antineuronal surface antibodies (p=0.01).Autoimmune-associated epilepsy was the long-term sequela in 43.73%, associated with cognitive and psychiatric disturbances in 81.73%. Independent predictors of developing epilepsy were difficult to treat seizures at onset (p=0.04), a high number of antiseizure medications (p<0.001), persisting interictal epileptiform discharges at follow-up (p<0.001) and poor response to immunotherapy during the acute phase (p<0.001).The recognition of seizures secondary to AE represents a rare chance for aetiology-driven seizures management. Early recognition and treatment at the pathogenic level may reduce the risk of long-term irreversible sequelae. However, the severity of seizures at onset is the major risk factor for the development of chronic epilepsy.This study provides class IV evidence for management recommendations." @default.
• W4287578625 created "2022-07-25" @default.
• W4287578625 creator A5005809141 @default.
• W4287578625 creator A5011786587 @default.
• W4287578625 creator A5017248165 @default.
• W4287578625 creator A5025475711 @default.
• W4287578625 creator A5026047659 @default.
• W4287578625 creator A5027652820 @default.
• W4287578625 creator A5028511207 @default.
• W4287578625 creator A5030365497 @default.
• W4287578625 creator A5039901601 @default.
• W4287578625 creator A5041210426 @default.
• W4287578625 creator A5041468356 @default.
• W4287578625 creator A5042610248 @default.
• W4287578625 creator A5042619844 @default.
• W4287578625 creator A5048792850 @default.
• W4287578625 creator A5049237819 @default.
• W4287578625 creator A5053193830 @default.
• W4287578625 creator A5060437525 @default.
• W4287578625 creator A5062771449 @default.
• W4287578625 creator A5063457670 @default.
• W4287578625 creator A5064448962 @default.
• W4287578625 creator A5076959356 @default.
• W4287578625 creator A5079266884 @default.
• W4287578625 creator A5085838749 @default.
• W4287578625 creator A5087346699 @default.
• W4287578625 creator A5087512489 @default.
• W4287578625 creator A5087984761 @default.
• W4287578625 date "2022-07-25" @default.
• W4287578625 modified "2023-10-17" @default.
• W4287578625 title "Epileptic phenotypes in autoimmune encephalitis: from acute symptomatic seizures to autoimmune-associated epilepsy" @default.
• W4287578625 cites W1698448760 @default.
• W4287578625 cites W2076763195 @default.
• W4287578625 cites W2110349010 @default.
• W4287578625 cites W2159439874 @default.
• W4287578625 cites W2163022996 @default.
• W4287578625 cites W2280783985 @default.
• W4287578625 cites W2586972945 @default.
• W4287578625 cites W2590448139 @default.
• W4287578625 cites W2592509339 @default.
• W4287578625 cites W2594644573 @default.
• W4287578625 cites W2612904569 @default.
• W4287578625 cites W2617258020 @default.
• W4287578625 cites W2671984035 @default.
• W4287578625 cites W2782339488 @default.
• W4287578625 cites W2783144549 @default.
• W4287578625 cites W2791304973 @default.
• W4287578625 cites W2791578370 @default.
• W4287578625 cites W2913472312 @default.
• W4287578625 cites W2914944710 @default.
• W4287578625 cites W2935721900 @default.
• W4287578625 cites W2937160316 @default.
• W4287578625 cites W2937321881 @default.
• W4287578625 cites W2964101940 @default.
• W4287578625 cites W2999177463 @default.
• W4287578625 cites W3034212049 @default.
• W4287578625 cites W3044703934 @default.
• W4287578625 cites W3082563548 @default.
• W4287578625 cites W3091932761 @default.
• W4287578625 cites W3134115353 @default.
• W4287578625 cites W3135701430 @default.
• W4287578625 cites W3163926470 @default.
• W4287578625 cites W3180930680 @default.
• W4287578625 cites W3205998300 @default.
• W4287578625 cites W4229699489 @default.
• W4287578625 doi "https://doi.org/10.1136/jnnp-2022-329195" @default.
• W4287578625 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35879055" @default.
• W4287578625 hasPublicationYear "2022" @default.
• W4287578625 type Work @default.
• W4287578625 citedByCount "9" @default.
• W4287578625 countsByYear W42875786252022 @default.
• W4287578625 countsByYear W42875786252023 @default.
• W4287578625 crossrefType "journal-article" @default.
• W4287578625 hasAuthorship W4287578625A5005809141 @default.
• W4287578625 hasAuthorship W4287578625A5011786587 @default.
• W4287578625 hasAuthorship W4287578625A5017248165 @default.
• W4287578625 hasAuthorship W4287578625A5025475711 @default.
• W4287578625 hasAuthorship W4287578625A5026047659 @default.
• W4287578625 hasAuthorship W4287578625A5027652820 @default.
• W4287578625 hasAuthorship W4287578625A5028511207 @default.
• W4287578625 hasAuthorship W4287578625A5030365497 @default.
• W4287578625 hasAuthorship W4287578625A5039901601 @default.
• W4287578625 hasAuthorship W4287578625A5041210426 @default.
• W4287578625 hasAuthorship W4287578625A5041468356 @default.
• W4287578625 hasAuthorship W4287578625A5042610248 @default.
• W4287578625 hasAuthorship W4287578625A5042619844 @default.
• W4287578625 hasAuthorship W4287578625A5048792850 @default.
• W4287578625 hasAuthorship W4287578625A5049237819 @default.
• W4287578625 hasAuthorship W4287578625A5053193830 @default.
• W4287578625 hasAuthorship W4287578625A5060437525 @default.
• W4287578625 hasAuthorship W4287578625A5062771449 @default.
• W4287578625 hasAuthorship W4287578625A5063457670 @default.
• W4287578625 hasAuthorship W4287578625A5064448962 @default.
• W4287578625 hasAuthorship W4287578625A5076959356 @default.
• W4287578625 hasAuthorship W4287578625A5079266884 @default.
• W4287578625 hasAuthorship W4287578625A5085838749 @default.
• W4287578625 hasAuthorship W4287578625A5087346699 @default.
• W4287578625 hasAuthorship W4287578625A5087512489 @default.

• next