FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4287701344> ?p ?o ?g. }

• W4287701344 endingPage "29" @default.
• W4287701344 startingPage "25" @default.
• W4287701344 abstract "To find the serum hsCRP (high sensitive C reactive protein) levels in type 2 Diabetes Mellitus (DM) patients and compare its level between type 2 DM patients and healthy control subjects. To find the relationship of hsCRP levels in type 2 DM with and without vascular complications. To find the correlation of hsCRP with HbA1c and duration of type 2 DM among cases and to find the optimum cut-off value for hsCRP among type 2 DM patients.The study was conducted on type 2 DM patients with or without microvascular or macrovascular complications and nondiabetic healthy controls from April 2017 to July 2018. Fasting plasma glucose, postprandial plasma glucose, HbA1C, and hsCRP were estimated. Duration of diabetes was noted. SPSS for Windows version22 software was used for statistical analysis. Chi2 or Fisher's exact test was applied to compare frequency distribution. The student t-test was applied to compare two independent means. Test of normality was performed before applying the statistical test for significance. The area under the curve (AUC) and sensitivity and specificity of HSCRP levels in DM2 at various cut-off values were calculated.The mean age of the patients 53.46±12.01 years with 49% among the age group 45 - 64 years and 62% were females. The mean value of hsCRP among diabetic subjects comes out to be 4.06 ± 2.59 mg/l, while among healthy controls is 0.93 ± 0.81 mg/l (p<0.0001). The mean duration of diabetes in our study is 6.90 ± 5.89 years with maximum cases had duration of diabetes between 1-5 years and a positive linear correlation with hsCRP (r=0.20; p=0.044). A positive linear correlation between hsCRP and HBA1C is found (r = 0.0507; p<0.0001). Among 100 cases, 71 cases were with overt complications of diabetes as either microvascular or macrovascular complications. Of these 71 cases with overt complications, 61.97% cases were with high risk levels of hsCRP (>3.0 mg/l). The mean value of hsCRP among cases with complications is 4.45 ± 2.74 mg/l while among cases without complications is 3.11 ± 1.89 mg/l (p=0.0176). The most common complication associated among the cases are microvascular complication in the form of diabetic retinopathy with mean hsCRP 4.61± 2.88 while the mean hsCRP was highest among the cases associated with cardiovascular complication as 5.37±3.10. In this study on 100 participants with type 2 diabetes mellitus, the maximum value of sensitivity of 89.00 % and specificity of 87.00% is found in diabetes at the best cut-off of serum hsCRP levels greater than 1.21 mg/L.hsCRP levels were high in type 2 diabetes mellitus with higher risk levels associated with macrovascular complications compared to microvascular complications. The levels of hsCRP correlated with duration of diabetes and HbA1c. Routine screening for future cardiovascular events in diabetes patients can be done with best cut-off value of hsCRP at 1.21 mg/L." @default.
• W4287701344 created "2022-07-26" @default.
• W4287701344 creator A5065381028 @default.
• W4287701344 creator A5073670795 @default.
• W4287701344 date "2020-08-01" @default.
• W4287701344 modified "2023-10-16" @default.
• W4287701344 title "To Study Relationship of Serum hsCRP with Type 2 Diabetes Mellitus, its Vascular Complications and Non-Diabetics - Case Control Study." @default.
• W4287701344 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32738836" @default.
• W4287701344 hasPublicationYear "2020" @default.
• W4287701344 type Work @default.
• W4287701344 citedByCount "2" @default.
• W4287701344 countsByYear W42877013442022 @default.
• W4287701344 crossrefType "journal-article" @default.
• W4287701344 hasAuthorship W4287701344A5065381028 @default.
• W4287701344 hasAuthorship W4287701344A5073670795 @default.
• W4287701344 hasConcept C126322002 @default.
• W4287701344 hasConcept C134018914 @default.
• W4287701344 hasConcept C2776914184 @default.
• W4287701344 hasConcept C2777180221 @default.
• W4287701344 hasConcept C2778199505 @default.
• W4287701344 hasConcept C2781195455 @default.
• W4287701344 hasConcept C2910068830 @default.
• W4287701344 hasConcept C555293320 @default.
• W4287701344 hasConcept C65409693 @default.
• W4287701344 hasConcept C71924100 @default.
• W4287701344 hasConcept C90924648 @default.
• W4287701344 hasConceptScore W4287701344C126322002 @default.
• W4287701344 hasConceptScore W4287701344C134018914 @default.
• W4287701344 hasConceptScore W4287701344C2776914184 @default.
• W4287701344 hasConceptScore W4287701344C2777180221 @default.
• W4287701344 hasConceptScore W4287701344C2778199505 @default.
• W4287701344 hasConceptScore W4287701344C2781195455 @default.
• W4287701344 hasConceptScore W4287701344C2910068830 @default.
• W4287701344 hasConceptScore W4287701344C555293320 @default.
• W4287701344 hasConceptScore W4287701344C65409693 @default.
• W4287701344 hasConceptScore W4287701344C71924100 @default.
• W4287701344 hasConceptScore W4287701344C90924648 @default.
• W4287701344 hasIssue "8" @default.
• W4287701344 hasLocation W42877013441 @default.
• W4287701344 hasOpenAccess W4287701344 @default.
• W4287701344 hasPrimaryLocation W42877013441 @default.
• W4287701344 hasRelatedWork W10605991 @default.
• W4287701344 hasRelatedWork W1479920 @default.
• W4287701344 hasRelatedWork W2192100 @default.
• W4287701344 hasRelatedWork W2397026 @default.
• W4287701344 hasRelatedWork W3526898 @default.
• W4287701344 hasRelatedWork W4827547 @default.
• W4287701344 hasRelatedWork W7896099 @default.
• W4287701344 hasRelatedWork W9343845 @default.
• W4287701344 hasRelatedWork W9552334 @default.
• W4287701344 hasRelatedWork W4445067 @default.
• W4287701344 hasVolume "68" @default.
• W4287701344 isParatext "false" @default.
• W4287701344 isRetracted "false" @default.
• W4287701344 workType "article" @default.