FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4287836357> ?p ?o ?g. }

• W4287836357 endingPage "1802" @default.
• W4287836357 startingPage "1802" @default.
• W4287836357 abstract "Chronic lymphocytic leukemia (CLL) has a variable clinical evolution, with some patients living treatment-free for decades while others require therapy shortly after diagnosis. In a consecutive series of 217 CLL patients, molecular biomarkers with prognostic value (IGHV status, TP53 mutations, and cytogenetics), whose analysis is recommended prior to treatment start, were studied at diagnosis. Multivariate analyses identified prognostic variables for overall survival (OS) and time to first treatment (TTFT) and validated the CLL-IPI and IPS-E variables for all or early-stage patients (Rai 0–2/Binet A), respectively. Unmutated IGHV was associated with shorter OS and TTFT, even for early-stage patients. Lymphocyte count was not statistically significant for TTFT of early-stage patients in multivariate analysis. Our results validate the prognostic value of IGHV mutational status at diagnosis for OS and TTFT, including for early stages. Our findings suggest a role for molecular and mutational analysis at diagnosis in future prospective studies." @default.
• W4287836357 created "2022-07-26" @default.
• W4287836357 creator A5000339773 @default.
• W4287836357 creator A5014949357 @default.
• W4287836357 creator A5018125442 @default.
• W4287836357 creator A5018621861 @default.
• W4287836357 creator A5045811667 @default.
• W4287836357 creator A5048162210 @default.
• W4287836357 creator A5061034413 @default.
• W4287836357 creator A5067785304 @default.
• W4287836357 creator A5068226450 @default.
• W4287836357 creator A5075456517 @default.
• W4287836357 creator A5081573140 @default.
• W4287836357 creator A5083740790 @default.
• W4287836357 creator A5091895855 @default.
• W4287836357 date "2022-07-25" @default.
• W4287836357 modified "2023-09-26" @default.
• W4287836357 title "Genetic Testing at Diagnosis Has Prognostic Value in Patients with Chronic Lymphocytic Leukemia including at Early Stages" @default.
• W4287836357 cites W1196637763 @default.
• W4287836357 cites W1243376384 @default.
• W4287836357 cites W1429374962 @default.
• W4287836357 cites W154103547 @default.
• W4287836357 cites W1565211228 @default.
• W4287836357 cites W1965851569 @default.
• W4287836357 cites W1967008538 @default.
• W4287836357 cites W1993986769 @default.
• W4287836357 cites W1994709165 @default.
• W4287836357 cites W2020069805 @default.
• W4287836357 cites W2038678963 @default.
• W4287836357 cites W2085442567 @default.
• W4287836357 cites W2105773020 @default.
• W4287836357 cites W2105921327 @default.
• W4287836357 cites W2142099365 @default.
• W4287836357 cites W2295348655 @default.
• W4287836357 cites W2318933236 @default.
• W4287836357 cites W2337485820 @default.
• W4287836357 cites W2608696803 @default.
• W4287836357 cites W2789078984 @default.
• W4287836357 cites W2790385276 @default.
• W4287836357 cites W2901396567 @default.
• W4287836357 cites W2978887976 @default.
• W4287836357 cites W3014127006 @default.
• W4287836357 cites W4213170825 @default.
• W4287836357 cites W4235474157 @default.
• W4287836357 cites W4251009301 @default.
• W4287836357 doi "https://doi.org/10.3390/diagnostics12081802" @default.
• W4287836357 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35892513" @default.
• W4287836357 hasPublicationYear "2022" @default.
• W4287836357 type Work @default.
• W4287836357 citedByCount "0" @default.
• W4287836357 crossrefType "journal-article" @default.
• W4287836357 hasAuthorship W4287836357A5000339773 @default.
• W4287836357 hasAuthorship W4287836357A5014949357 @default.
• W4287836357 hasAuthorship W4287836357A5018125442 @default.
• W4287836357 hasAuthorship W4287836357A5018621861 @default.
• W4287836357 hasAuthorship W4287836357A5045811667 @default.
• W4287836357 hasAuthorship W4287836357A5048162210 @default.
• W4287836357 hasAuthorship W4287836357A5061034413 @default.
• W4287836357 hasAuthorship W4287836357A5067785304 @default.
• W4287836357 hasAuthorship W4287836357A5068226450 @default.
• W4287836357 hasAuthorship W4287836357A5075456517 @default.
• W4287836357 hasAuthorship W4287836357A5081573140 @default.
• W4287836357 hasAuthorship W4287836357A5083740790 @default.
• W4287836357 hasAuthorship W4287836357A5091895855 @default.
• W4287836357 hasBestOaLocation W42878363571 @default.
• W4287836357 hasConcept C105795698 @default.
• W4287836357 hasConcept C126322002 @default.
• W4287836357 hasConcept C143998085 @default.
• W4287836357 hasConcept C146357865 @default.
• W4287836357 hasConcept C151730666 @default.
• W4287836357 hasConcept C161584116 @default.
• W4287836357 hasConcept C2777609679 @default.
• W4287836357 hasConcept C2777938653 @default.
• W4287836357 hasConcept C2778461978 @default.
• W4287836357 hasConcept C33923547 @default.
• W4287836357 hasConcept C38180746 @default.
• W4287836357 hasConcept C71924100 @default.
• W4287836357 hasConcept C86803240 @default.
• W4287836357 hasConceptScore W4287836357C105795698 @default.
• W4287836357 hasConceptScore W4287836357C126322002 @default.
• W4287836357 hasConceptScore W4287836357C143998085 @default.
• W4287836357 hasConceptScore W4287836357C146357865 @default.
• W4287836357 hasConceptScore W4287836357C151730666 @default.
• W4287836357 hasConceptScore W4287836357C161584116 @default.
• W4287836357 hasConceptScore W4287836357C2777609679 @default.
• W4287836357 hasConceptScore W4287836357C2777938653 @default.
• W4287836357 hasConceptScore W4287836357C2778461978 @default.
• W4287836357 hasConceptScore W4287836357C33923547 @default.
• W4287836357 hasConceptScore W4287836357C38180746 @default.
• W4287836357 hasConceptScore W4287836357C71924100 @default.
• W4287836357 hasConceptScore W4287836357C86803240 @default.
• W4287836357 hasFunder F4320328697 @default.
• W4287836357 hasIssue "8" @default.
• W4287836357 hasLocation W42878363571 @default.
• W4287836357 hasLocation W42878363572 @default.
• W4287836357 hasLocation W42878363573 @default.
• W4287836357 hasLocation W42878363574 @default.
• W4287836357 hasOpenAccess W4287836357 @default.

• next