FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4287921849> ?p ?o ?g. }

• W4287921849 abstract "BACKGROUND: Over the past few years, there has been an increasing interest to view the diagnosis of Familial hypercholesterolemia (FH) through the lens of the biopsychosocial model. However, other than a few epidemiological surveys, there is a dearth of studies from emerging economies that have examined FH using the biological, psychological and socio-environmental facets of the aforementioned model. AIM. The three aims of the current study were as follows: (i) to examine the psychosocial status among patients with genetically confirmed FH, (ii) to compare the intellectual capacity and cognitive outcomes with a reference group, and (iii) to examine the relationship between health literacy and cognitive functioning. METHOD: Consecutive FH patients referred to the lipid clinic at a tertiary care center for an expert opinion were recruited into this study, conducted from September 2019 to March 2020. Information regarding psychosocial functioning, health literacy, quality of life, and affective ranges were surveyed. Indices of current reasoning ability (attention and concentration, memory, and executive functioning) were compared with an age-matched reference group. The current hypothesis also explored the impact of FH on health literacy and cognition. RESULT: A total of 70 participants out of 106 (response rate: 66.0%) initially agreed to participate. However, 18 out of 70 dropped out of the study, yielding a final total of 52 FH patients. With 27 (51.9%) males and 25 (48.1%) females, the mean participant age stood at 37.2 years (SD=9.2), ranging from 21 to 52 years of age. In the psychosocial data, thirty-two percent (n=17) of them had anxiety (HADS&ge; 8), and twenty-five percent (n=13) had depressive symptoms (HADS&ge; 8). The performance of the FH patients was significantly impaired compared to the control group on the indices of current reasoning ability and all domains of cognitive functioning. In univariate analysis conducted to compare cognitive functioning with health literacy status, only indices of attention and concentration emerged as being significant. CONCLUSION: To date, there are only a few studies employing the biopsychosocial paradigm to investigate the FH population. The current study indicates that the FH population is marked by an impediment in almost all of the core features that are characteristically assessed by the biopsychosocial approach." @default.
• W4287921849 created "2022-07-26" @default.
• W4287921849 creator A5015252112 @default.
• W4287921849 creator A5022449336 @default.
• W4287921849 creator A5032244501 @default.
• W4287921849 creator A5033018818 @default.
• W4287921849 creator A5058131373 @default.
• W4287921849 creator A5060041254 @default.
• W4287921849 creator A5067061524 @default.
• W4287921849 creator A5079369010 @default.
• W4287921849 date "2022-07-26" @default.
• W4287921849 modified "2023-09-30" @default.
• W4287921849 title "A Comprehensive Neuropsychological Study of Familial Hypercholesterolemia and Its Relationship with Psychosocial Functioning: A Biopsychosocial Approach" @default.
• W4287921849 doi "https://doi.org/10.20944/preprints202207.0397.v1" @default.
• W4287921849 hasPublicationYear "2022" @default.
• W4287921849 type Work @default.
• W4287921849 citedByCount "0" @default.
• W4287921849 crossrefType "posted-content" @default.
• W4287921849 hasAuthorship W4287921849A5015252112 @default.
• W4287921849 hasAuthorship W4287921849A5022449336 @default.
• W4287921849 hasAuthorship W4287921849A5032244501 @default.
• W4287921849 hasAuthorship W4287921849A5033018818 @default.
• W4287921849 hasAuthorship W4287921849A5058131373 @default.
• W4287921849 hasAuthorship W4287921849A5060041254 @default.
• W4287921849 hasAuthorship W4287921849A5067061524 @default.
• W4287921849 hasAuthorship W4287921849A5079369010 @default.
• W4287921849 hasBestOaLocation W42879218491 @default.
• W4287921849 hasConcept C118552586 @default.
• W4287921849 hasConcept C134290984 @default.
• W4287921849 hasConcept C137886200 @default.
• W4287921849 hasConcept C14216870 @default.
• W4287921849 hasConcept C150966472 @default.
• W4287921849 hasConcept C15744967 @default.
• W4287921849 hasConcept C169900460 @default.
• W4287921849 hasConcept C2779951463 @default.
• W4287921849 hasConcept C542102704 @default.
• W4287921849 hasConcept C70410870 @default.
• W4287921849 hasConcept C71924100 @default.
• W4287921849 hasConcept C74909509 @default.
• W4287921849 hasConceptScore W4287921849C118552586 @default.
• W4287921849 hasConceptScore W4287921849C134290984 @default.
• W4287921849 hasConceptScore W4287921849C137886200 @default.
• W4287921849 hasConceptScore W4287921849C14216870 @default.
• W4287921849 hasConceptScore W4287921849C150966472 @default.
• W4287921849 hasConceptScore W4287921849C15744967 @default.
• W4287921849 hasConceptScore W4287921849C169900460 @default.
• W4287921849 hasConceptScore W4287921849C2779951463 @default.
• W4287921849 hasConceptScore W4287921849C542102704 @default.
• W4287921849 hasConceptScore W4287921849C70410870 @default.
• W4287921849 hasConceptScore W4287921849C71924100 @default.
• W4287921849 hasConceptScore W4287921849C74909509 @default.
• W4287921849 hasLocation W42879218491 @default.
• W4287921849 hasLocation W42879218492 @default.
• W4287921849 hasOpenAccess W4287921849 @default.
• W4287921849 hasPrimaryLocation W42879218491 @default.
• W4287921849 hasRelatedWork W1516907177 @default.
• W4287921849 hasRelatedWork W1859768362 @default.
• W4287921849 hasRelatedWork W2052916324 @default.
• W4287921849 hasRelatedWork W2056052817 @default.
• W4287921849 hasRelatedWork W2080607739 @default.
• W4287921849 hasRelatedWork W2102004906 @default.
• W4287921849 hasRelatedWork W2617278948 @default.
• W4287921849 hasRelatedWork W4287921849 @default.
• W4287921849 hasRelatedWork W4293103783 @default.
• W4287921849 hasRelatedWork W4307033318 @default.
• W4287921849 isParatext "false" @default.
• W4287921849 isRetracted "false" @default.
• W4287921849 workType "article" @default.