FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4287922027> ?p ?o ?g. }

• W4287922027 abstract "The systemic immune-inflammation index (SII), system inflammation response index (SIRI), neutrophil/high-density lipoprotein (HDL) ratio (NHR), lymphocyte/HDL ratio (LHR), monocyte/HDL ratio (MHR), and platelet/HDL ratio (PHR) have been recently investigated as new markers for inflammation. The purpose of this research is to use large-scale clinical data to discuss and compare the predictive ability of the SII, SIRI, NHR, LHR, MHR, and PHR in patients with schizophrenia (SCZ) and bipolar disorder (BD), to investigate potential biomarkers.In this retrospective, naturalistic, cross-sectional study, we collected the hematological parameter data of 13,329 patients with SCZ, 4,061 patients with BD manic episodes (BD-M), and 1,944 patients with BD depressive episodes (BD-D), and 5,810 healthy subjects served as the healthy control (HC) group. The differences in the SII, SIRI, NHR, LHR, MHR, and PHR were analyzed, and a receiver operating characteristic (ROC) curve was used to analyze the diagnostic potential of these parameters.Compared with the HC group, the values of the SII, SIRI, NHR, LHR, MHR, and PHR and the levels of neutrophils, monocytes, and triglycerides (TG) were higher in SCZ and BD groups, and levels of platelets, cholesterol (CHO), HDL, low-density lipoprotein (LDL), and apoprotein B (Apo B) were lower in SCZ and BD groups. Compared to the BD group, the values of the SIRI, lymphocytes, monocytes, and HDL were lower and the values of the SII, NHR, PHR, and platelet were higher in the SCZ group. In contrast to the BD-D group, the values of the SII; SIRI; NHR; and MHR; and levels of neutrophils, monocytes, and platelets were higher in the BD-M group, and the levels of CHO, TG, LDL, and Apo B were lower in the BD-M group. The MHR and NHR were predictors for differentiating the SCZ group from the HC group; the SIRI, NHR, and MHR were predictors for differentiating the BD-M group from the HC group; and the MHR was a predictor for differentiating the BD-D group from the HC group. The combination model of the indicators improved diagnostic effectiveness.Our study highlights the role of systemic inflammation in the pathophysiology of SCZ, BD-M, and BD-D, the association between inflammation and lipid metabolism, and these inflammation and lipid metabolism indicators showed different variation patterns in SCZ, BD-D, and BD-M." @default.
• W4287922027 created "2022-07-26" @default.
• W4287922027 creator A5003728286 @default.
• W4287922027 creator A5032208076 @default.
• W4287922027 creator A5035898128 @default.
• W4287922027 creator A5041242808 @default.
• W4287922027 creator A5045387296 @default.
• W4287922027 creator A5058408384 @default.
• W4287922027 creator A5071257560 @default.
• W4287922027 creator A5081093007 @default.
• W4287922027 creator A5081840211 @default.
• W4287922027 creator A5085010886 @default.
• W4287922027 date "2022-07-26" @default.
• W4287922027 modified "2023-10-10" @default.
• W4287922027 title "Investigation of systemic immune-inflammation index, neutrophil/high-density lipoprotein ratio, lymphocyte/high-density lipoprotein ratio, and monocyte/high-density lipoprotein ratio as indicators of inflammation in patients with schizophrenia and bipolar disorder" @default.
• W4287922027 cites W1984344128 @default.
• W4287922027 cites W2033883349 @default.
• W4287922027 cites W2096262020 @default.
• W4287922027 cites W2125808969 @default.
• W4287922027 cites W2160408631 @default.
• W4287922027 cites W2399060753 @default.
• W4287922027 cites W2565906784 @default.
• W4287922027 cites W2607874374 @default.
• W4287922027 cites W2611267400 @default.
• W4287922027 cites W2768432370 @default.
• W4287922027 cites W2802032956 @default.
• W4287922027 cites W2888647009 @default.
• W4287922027 cites W2897272295 @default.
• W4287922027 cites W2899510584 @default.
• W4287922027 cites W2900508006 @default.
• W4287922027 cites W2982028900 @default.
• W4287922027 cites W2982460940 @default.
• W4287922027 cites W2987897597 @default.
• W4287922027 cites W3014896255 @default.
• W4287922027 cites W3025479624 @default.
• W4287922027 cites W3033427258 @default.
• W4287922027 cites W3034765486 @default.
• W4287922027 cites W3035238213 @default.
• W4287922027 cites W3043176161 @default.
• W4287922027 cites W3080873582 @default.
• W4287922027 cites W3082748206 @default.
• W4287922027 cites W3083631134 @default.
• W4287922027 cites W3093963285 @default.
• W4287922027 cites W3109192486 @default.
• W4287922027 cites W3112651280 @default.
• W4287922027 cites W3116545793 @default.
• W4287922027 cites W3119017187 @default.
• W4287922027 cites W3119552585 @default.
• W4287922027 cites W3121220599 @default.
• W4287922027 cites W3121535561 @default.
• W4287922027 cites W3121703177 @default.
• W4287922027 cites W3133744469 @default.
• W4287922027 cites W3135384619 @default.
• W4287922027 cites W3154700704 @default.
• W4287922027 cites W3160850430 @default.
• W4287922027 cites W3179592424 @default.
• W4287922027 cites W3193831468 @default.
• W4287922027 cites W3207808840 @default.
• W4287922027 cites W3209317327 @default.
• W4287922027 cites W3212452470 @default.
• W4287922027 cites W4200422255 @default.
• W4287922027 cites W4200471126 @default.
• W4287922027 cites W4210998119 @default.
• W4287922027 cites W4214744136 @default.
• W4287922027 cites W4221028502 @default.
• W4287922027 cites W4224292027 @default.
• W4287922027 cites W4225344221 @default.
• W4287922027 cites W4225919562 @default.
• W4287922027 doi "https://doi.org/10.3389/fpsyt.2022.941728" @default.
• W4287922027 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35958647" @default.
• W4287922027 hasPublicationYear "2022" @default.
• W4287922027 type Work @default.
• W4287922027 citedByCount "12" @default.
• W4287922027 countsByYear W42879220272023 @default.
• W4287922027 crossrefType "journal-article" @default.
• W4287922027 hasAuthorship W4287922027A5003728286 @default.
• W4287922027 hasAuthorship W4287922027A5032208076 @default.
• W4287922027 hasAuthorship W4287922027A5035898128 @default.
• W4287922027 hasAuthorship W4287922027A5041242808 @default.
• W4287922027 hasAuthorship W4287922027A5045387296 @default.
• W4287922027 hasAuthorship W4287922027A5058408384 @default.
• W4287922027 hasAuthorship W4287922027A5071257560 @default.
• W4287922027 hasAuthorship W4287922027A5081093007 @default.
• W4287922027 hasAuthorship W4287922027A5081840211 @default.
• W4287922027 hasAuthorship W4287922027A5085010886 @default.
• W4287922027 hasBestOaLocation W42879220271 @default.
• W4287922027 hasConcept C118552586 @default.
• W4287922027 hasConcept C126322002 @default.
• W4287922027 hasConcept C134018914 @default.
• W4287922027 hasConcept C203014093 @default.
• W4287922027 hasConcept C2776174506 @default.
• W4287922027 hasConcept C2776252253 @default.
• W4287922027 hasConcept C2776412080 @default.
• W4287922027 hasConcept C2776914184 @default.
• W4287922027 hasConcept C2777761686 @default.
• W4287922027 hasConcept C2778163477 @default.
• W4287922027 hasConcept C2778541603 @default.
• W4287922027 hasConcept C2778963024 @default.
• W4287922027 hasConcept C2780541478 @default.
• W4287922027 hasConcept C2781184567 @default.

• next