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- W4287930269 abstract "Drug discovery has been one of the most widely studied areas of research in the field of science and technology; a new disease has been emerging every year, but the rate of drug discovery in comparison is very low. Fungi, bacteria, and plants have been the major contributors in drug discovery for many decades, but recent studies have shown two major candidates microalgae and cyanobacteria showing huge potential as a source for novel compounds. These organisms are rich in bioactive compounds particularly belonging to the group of alkaloids, tannins, lignins, flavonoids, and carotenoids. Genome studies of cyanobacteria and microalgae species also revealed the potential of these organisms to produce diverse and complex nature of secondary metabolites belonging to nonribosomal peptides, polyketides, or hybrid peptide polyketide compounds. These compounds exhibit a remarkable array of biological activity, and many of them are clinically valuable antimicrobial, antifungal, antiparasitic, antitumor, and immunosuppressive agents. Therefore, in this chapter, we will discuss important natural compounds discovered from microalgae and cyanobacteria. In addition, we will also discuss the genome mining technique in drug discovery with special emphasis on drug discovery from microalgae and cyanobacteria. This technique offers a new alternative approach over the traditional drug discovery method by coupling several bioinformatic tools with next-generation sequencing technology for genetic annotation and identification of important biosynthetic gene clusters (BGCs)." @default.
- W4287930269 created "2022-07-26" @default.
- W4287930269 creator A5040280488 @default.
- W4287930269 creator A5045838266 @default.
- W4287930269 date "2022-01-01" @default.
- W4287930269 modified "2023-10-16" @default.
- W4287930269 title "Microalgae and Cyanobacteria: A Potential Source for Drug Discovery Using Genome Mining Approach" @default.
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