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- W4287958889 abstract "Aim: To unveil a putative correlation between phage genome flexibility and virion morphogenesis yield. Materials & methods: A deeper analysis of the mechanical properties of three Pseudomonas aeruginosa lytic phage genomes was undertaken, together with full genome cyclizability calculations. Results & conclusion: A putative correlation was established among phage genome flexibility, eclipse timeframe and virion particle morphogenesis yield, with a more flexible phage genome leading to a higher burst size and a more rigid phage genome leading to lower burst sizes. The results obtained are highly relevant to understand the influence of the phage genome plasticity on the virion morphogenesis yield inside the infected bacterial host cells and assumes particular relevance in the actual context of bacterial resistance to antibiotics." @default.
- W4287958889 created "2022-07-26" @default.
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- W4287958889 date "2022-09-01" @default.
- W4287958889 modified "2023-10-15" @default.
- W4287958889 title "<i>Pseudomonas</i>-tailed lytic phages: genome mechanical analysis and putative correlation with virion morphogenesis yield" @default.
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- W4287958889 doi "https://doi.org/10.2217/fmb-2021-0293" @default.
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