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- W4287961302 abstract "Easy management and quality patient compliance are essential attributes for the development of any drug delivery system, oral drug delivery system, being the most convenient, least expensive and safest method is the preferred route amongst all. “Mouth Dissolving Tablets [MDTs]” have received ever-boosting demand during the last decades. These tablets are made to dissolve in the saliva very quickly, within a few seconds, and are true tablets that disperse quickly. Difficulty in swallowing conventional tablets and capsules problem can be resolved by the new drug delivery system by making “oral tablets” [MDTs]. Fast-dispersing tablets (FDTs), categorized under the umbrella of MDT have become a fast-growing area in the pharmaceutical industry. Fast disintegrating tablets (FDTs) are those dosage forms that are placed on the tongue or in the mouth cavity, dispersed or dissolved immediately, and release the drug, within a few seconds without the need for water. This may be due to the action of superdisintegrant or enlarging the pore structure in the formation etc. Fast disintegrating tablets (FDTs) aim to design dosage forms that are ready to be administered with no side effects, providing an immediate release for the quick action and improved bioavailability, to achieve better patient compliance. The purpose of this review article is to provide a framework for the composition of FDT, the prerequisite for the selection of key ingredients, its desirable features and development challenges, and various technologies developed to achieve fast dissolution/dispersion of tablets in the oral cavity. Besides this, the review also explores the various key mechanism of tablet disintegration techniques used for the formulation of oral mouth dissolving tablets along with its evaluation." @default.
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- W4287961302 date "2022-07-15" @default.
- W4287961302 modified "2023-10-01" @default.
- W4287961302 title "Fast-dispersing Tablets (FDT) Based Technology: A Review at A Glance" @default.
- W4287961302 doi "https://doi.org/10.47583/ijpsrr.2022.v75i01.024" @default.
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