Matches in SemOpenAlex for { <https://semopenalex.org/work/W4287988309> ?p ?o ?g. }
- W4287988309 endingPage "6227" @default.
- W4287988309 startingPage "6214" @default.
- W4287988309 abstract "The hierarchical three-dimensional (3D)-printing scaffolds based on microbial polyester poly(3-hydroxybutyrate-co-4-hydroxybutyrate) (P34HB) were designed and used for bone tissue engineering via surface functionalization on 3D-printed (P34HB) scaffolds using polydopamine (PDA)-mediated recombinant human bone morphogenetic protein-2 (BMP2), leading to enhanced bone formation in a rat model with a calvarial critical-size bone defect. Taking advantage of the adhesive property of PDA under alkaline and aerobic conditions, osteogenic BMP2 was captured on the surface of PHA scaffolds, resulting in their enhanced osteogenic bioactivity, better stem cell adhesion and proliferation, and sustainable release of a bioactive substance over a period of 30 days. These contributed to notable differences in alkaline phosphatase (ALP) activity, mineralization, expressions of osteogenesis-related genes, as well as finally enhanced in vivo bone formation in rats. The functionalized 3D-printed P34HB scaffolds via the PDA-mediated osteogenic activity were developed as a versatile platform for bone tissue regeneration." @default.
- W4287988309 created "2022-07-26" @default.
- W4287988309 creator A5029360035 @default.
- W4287988309 creator A5041124659 @default.
- W4287988309 creator A5044470813 @default.
- W4287988309 creator A5052883326 @default.
- W4287988309 creator A5069311365 @default.
- W4287988309 creator A5073568638 @default.
- W4287988309 creator A5085123678 @default.
- W4287988309 creator A5089070184 @default.
- W4287988309 creator A5089495172 @default.
- W4287988309 date "2022-01-01" @default.
- W4287988309 modified "2023-09-27" @default.
- W4287988309 title "Enhanced bone regeneration <i>via</i> PHA scaffolds coated with polydopamine-captured BMP2" @default.
- W4287988309 cites W1747547838 @default.
- W4287988309 cites W1974096559 @default.
- W4287988309 cites W1987190449 @default.
- W4287988309 cites W1988447859 @default.
- W4287988309 cites W1992947455 @default.
- W4287988309 cites W2001579238 @default.
- W4287988309 cites W2001633027 @default.
- W4287988309 cites W2001903709 @default.
- W4287988309 cites W2006950202 @default.
- W4287988309 cites W2013980488 @default.
- W4287988309 cites W2015998307 @default.
- W4287988309 cites W2017545194 @default.
- W4287988309 cites W2018922007 @default.
- W4287988309 cites W2033257382 @default.
- W4287988309 cites W2033691014 @default.
- W4287988309 cites W2033954341 @default.
- W4287988309 cites W2049906701 @default.
- W4287988309 cites W2070823629 @default.
- W4287988309 cites W2079860226 @default.
- W4287988309 cites W2092858957 @default.
- W4287988309 cites W2154457110 @default.
- W4287988309 cites W2157962408 @default.
- W4287988309 cites W2168789685 @default.
- W4287988309 cites W2191751320 @default.
- W4287988309 cites W2267854315 @default.
- W4287988309 cites W2322562148 @default.
- W4287988309 cites W2619538167 @default.
- W4287988309 cites W2758208288 @default.
- W4287988309 cites W2761181567 @default.
- W4287988309 cites W2767857660 @default.
- W4287988309 cites W2769557047 @default.
- W4287988309 cites W2781510895 @default.
- W4287988309 cites W2790970835 @default.
- W4287988309 cites W2809252818 @default.
- W4287988309 cites W2809255947 @default.
- W4287988309 cites W2889142294 @default.
- W4287988309 cites W2898440675 @default.
- W4287988309 cites W2907185858 @default.
- W4287988309 cites W2919610926 @default.
- W4287988309 cites W2954251291 @default.
- W4287988309 cites W2960571250 @default.
- W4287988309 cites W2970291595 @default.
- W4287988309 cites W2997485689 @default.
- W4287988309 cites W3004173882 @default.
- W4287988309 cites W3014495188 @default.
- W4287988309 cites W3014829492 @default.
- W4287988309 cites W3019535632 @default.
- W4287988309 cites W3033225111 @default.
- W4287988309 cites W3039929706 @default.
- W4287988309 cites W3047357591 @default.
- W4287988309 cites W3087239745 @default.
- W4287988309 cites W3087731201 @default.
- W4287988309 cites W3092212970 @default.
- W4287988309 cites W3094253913 @default.
- W4287988309 cites W3094610157 @default.
- W4287988309 cites W3094760424 @default.
- W4287988309 cites W3111466767 @default.
- W4287988309 cites W3115256569 @default.
- W4287988309 cites W3137815823 @default.
- W4287988309 cites W3155020406 @default.
- W4287988309 cites W3168088103 @default.
- W4287988309 cites W3169734251 @default.
- W4287988309 cites W3197821249 @default.
- W4287988309 cites W4200091975 @default.
- W4287988309 cites W4214748463 @default.
- W4287988309 doi "https://doi.org/10.1039/d2tb01122k" @default.
- W4287988309 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35920210" @default.
- W4287988309 hasPublicationYear "2022" @default.
- W4287988309 type Work @default.
- W4287988309 citedByCount "3" @default.
- W4287988309 countsByYear W42879883092022 @default.
- W4287988309 countsByYear W42879883092023 @default.
- W4287988309 crossrefType "journal-article" @default.
- W4287988309 hasAuthorship W4287988309A5029360035 @default.
- W4287988309 hasAuthorship W4287988309A5041124659 @default.
- W4287988309 hasAuthorship W4287988309A5044470813 @default.
- W4287988309 hasAuthorship W4287988309A5052883326 @default.
- W4287988309 hasAuthorship W4287988309A5069311365 @default.
- W4287988309 hasAuthorship W4287988309A5073568638 @default.
- W4287988309 hasAuthorship W4287988309A5085123678 @default.
- W4287988309 hasAuthorship W4287988309A5089070184 @default.
- W4287988309 hasAuthorship W4287988309A5089495172 @default.
- W4287988309 hasConcept C101414908 @default.
- W4287988309 hasConcept C111696902 @default.