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- W4288033241 abstract "Abstract Background The efficacy of interventions that provide long-term relief of genitourinary symptoms of menopause has not been determined. Objectives The authors sought to evaluate radiofrequency and hybrid fractional laser (HFL) treatments for menopausal vulvovaginal symptoms. Methods Thirty-one postmenopausal women completed all treatments and at least 1 follow-up. Outcomes included the Vulvovaginal Symptom Questionnaire (VSQ), Vaginal Laxity Questionnaire (VLQ), Urogenital Distress Short Form, Incontinence Impact Questionnaire (IIQ), Female Sexual Function Index (FSFI), laxity measurements via a vaginal biometric analyzer probe, and gene expression studies. Results Mean VSQ score decreased 2.93 (P = 0.0162), 4.07 (P = 0.0035), and 4.78 (P = 0.0089) among placebo, dual, and HFL groups 3 months posttreatment and decreased to 3.3 (P = 0.0215) for dual patients at 6 months. FSFI scores increased in the desire domain for placebo and dual groups and in arousal, lubrication, orgasm, satisfaction, and pain domains for the HFL group 3 and 6 months posttreatment. An increase of 1.14 in VLQ score (P = 0.0294) was noted 3 months and 2.2 (P = 0.002) 6 months following dual treatment. There was also a mean decrease of 15.3 (P = 0.0069) in IIQ score for HFL patients at 3 months. Dual, HFL, and RF treatments resulted in statistically significant decreases in collagen I, elastin, and lysyl oxidase expression. Conclusions Several self-reported improvements were noted, particularly among HFL, dual, and placebo groups 3 and 6 months posttreatment. Objective biopsy analysis illustrated decreased gene expression, suggesting that treatments did not stimulate new extracellular matrix production. Level of Evidence: 2" @default.
- W4288033241 created "2022-07-27" @default.
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- W4288033241 date "2022-07-27" @default.
- W4288033241 modified "2023-10-13" @default.
- W4288033241 title "A Randomized, Placebo-Controlled Trial Evaluating the Single and Combined Efficacy of Radiofrequency and Hybrid Fractional Laser for Nonsurgical Aesthetic Genital Procedures in Post-Menopausal Women" @default.
- W4288033241 cites W1197077700 @default.
- W4288033241 cites W1227345485 @default.
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- W4288033241 cites W1966672500 @default.
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- W4288033241 cites W1988316622 @default.
- W4288033241 cites W2002413950 @default.
- W4288033241 cites W2038810061 @default.
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- W4288033241 doi "https://doi.org/10.1093/asj/sjac202" @default.
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