FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288045153> ?p ?o ?g. }

• W4288045153 endingPage "103037" @default.
• W4288045153 startingPage "103037" @default.
• W4288045153 abstract "To evaluate the efficacy of 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in the treatment of high-grade squamous intraepithelial lesions of the cervix (HSIL). This retrospective study included 22 female patients with histologically confirmed HSIL and high-risk human papillomavirus (HR-HPV) infections. Patients were treated with ALA-PDT once a week for a total of 6 times. All patients had a follow-up period of 3 months and 6 months. The assessment of effectiveness of ALA-PDT was performed by ThinPrep cytology test (TCT), HPV DNA assay, HPV E6/E7 mRNA examination, colposcopy, biopsy, and immunohistochemistry detection. Three months after 5-ALA PDT, the histologic disappearance rate was 81.82% (18/22), while the HPV clearance rate was 54.55% (12/22). At the 6 months checkpoint, the HSIL disappearance rate was 90.91% (20/22) and the HPV clearance rate was 86.36% (19/22). Before PDT, 68.18% of patients (15/22) were confirmed with TCT abnormalities, while only one patient (1/22, 4.55%) was abnormal in the TCT test at 6 months checkpoint. All participants were found HPV E6/E7 mRNA positive initially, while the HPV E6/E7 mRNA negative rate was 90.91% (20/22) at 6 months checkpoint. Additionally, we found a significant difference of the expression of CD4+ and CD8+ T cells and HPV E6 and E7 proteins before ALA-PDT and at 3 months follow-up (P < 0.01). No severe side effects were seen. Topical 5-ALA PDT is an effective treatment for cervical HSIL with HR-HPV infection." @default.
• W4288045153 created "2022-07-27" @default.
• W4288045153 creator A5012655191 @default.
• W4288045153 creator A5018073672 @default.
• W4288045153 creator A5046084411 @default.
• W4288045153 creator A5048379858 @default.
• W4288045153 creator A5072050728 @default.
• W4288045153 creator A5074154889 @default.
• W4288045153 date "2022-09-01" @default.
• W4288045153 modified "2023-09-26" @default.
• W4288045153 title "Topical 5-aminolevulinic acid photodynamic therapy for cervical high-grade squamous intraepithelial lesions" @default.
• W4288045153 cites W2000070061 @default.
• W4288045153 cites W2047550659 @default.
• W4288045153 cites W2067793818 @default.
• W4288045153 cites W2121680483 @default.
• W4288045153 cites W2323529352 @default.
• W4288045153 cites W2489063059 @default.
• W4288045153 cites W2546514719 @default.
• W4288045153 cites W2550073245 @default.
• W4288045153 cites W2580399831 @default.
• W4288045153 cites W2587071457 @default.
• W4288045153 cites W2588914628 @default.
• W4288045153 cites W2590947287 @default.
• W4288045153 cites W2664931613 @default.
• W4288045153 cites W2750092411 @default.
• W4288045153 cites W2797666055 @default.
• W4288045153 cites W2891836094 @default.
• W4288045153 cites W2957265054 @default.
• W4288045153 cites W2969159587 @default.
• W4288045153 cites W3001262658 @default.
• W4288045153 cites W3009472222 @default.
• W4288045153 cites W3015112546 @default.
• W4288045153 cites W3045996770 @default.
• W4288045153 cites W3128646645 @default.
• W4288045153 cites W3132940303 @default.
• W4288045153 cites W3159425224 @default.
• W4288045153 cites W3172022498 @default.
• W4288045153 cites W3196524527 @default.
• W4288045153 cites W3199709841 @default.
• W4288045153 cites W3204203203 @default.
• W4288045153 cites W3208767951 @default.
• W4288045153 cites W4214873606 @default.
• W4288045153 cites W3189296973 @default.
• W4288045153 doi "https://doi.org/10.1016/j.pdpdt.2022.103037" @default.
• W4288045153 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35905829" @default.
• W4288045153 hasPublicationYear "2022" @default.
• W4288045153 type Work @default.
• W4288045153 citedByCount "1" @default.
• W4288045153 countsByYear W42880451532023 @default.
• W4288045153 crossrefType "journal-article" @default.
• W4288045153 hasAuthorship W4288045153A5012655191 @default.
• W4288045153 hasAuthorship W4288045153A5018073672 @default.
• W4288045153 hasAuthorship W4288045153A5046084411 @default.
• W4288045153 hasAuthorship W4288045153A5048379858 @default.
• W4288045153 hasAuthorship W4288045153A5072050728 @default.
• W4288045153 hasAuthorship W4288045153A5074154889 @default.
• W4288045153 hasConcept C121608353 @default.
• W4288045153 hasConcept C126322002 @default.
• W4288045153 hasConcept C178790620 @default.
• W4288045153 hasConcept C185592680 @default.
• W4288045153 hasConcept C204232928 @default.
• W4288045153 hasConcept C2775934546 @default.
• W4288045153 hasConcept C2776117191 @default.
• W4288045153 hasConcept C2777740455 @default.
• W4288045153 hasConcept C2778220009 @default.
• W4288045153 hasConcept C2781323092 @default.
• W4288045153 hasConcept C71924100 @default.
• W4288045153 hasConcept C90924648 @default.
• W4288045153 hasConceptScore W4288045153C121608353 @default.
• W4288045153 hasConceptScore W4288045153C126322002 @default.
• W4288045153 hasConceptScore W4288045153C178790620 @default.
• W4288045153 hasConceptScore W4288045153C185592680 @default.
• W4288045153 hasConceptScore W4288045153C204232928 @default.
• W4288045153 hasConceptScore W4288045153C2775934546 @default.
• W4288045153 hasConceptScore W4288045153C2776117191 @default.
• W4288045153 hasConceptScore W4288045153C2777740455 @default.
• W4288045153 hasConceptScore W4288045153C2778220009 @default.
• W4288045153 hasConceptScore W4288045153C2781323092 @default.
• W4288045153 hasConceptScore W4288045153C71924100 @default.
• W4288045153 hasConceptScore W4288045153C90924648 @default.
• W4288045153 hasFunder F4320321001 @default.
• W4288045153 hasLocation W42880451531 @default.
• W4288045153 hasLocation W42880451532 @default.
• W4288045153 hasOpenAccess W4288045153 @default.
• W4288045153 hasPrimaryLocation W42880451531 @default.
• W4288045153 hasRelatedWork W2025105594 @default.
• W4288045153 hasRelatedWork W2184317297 @default.
• W4288045153 hasRelatedWork W2398876125 @default.
• W4288045153 hasRelatedWork W2410812281 @default.
• W4288045153 hasRelatedWork W2418059156 @default.
• W4288045153 hasRelatedWork W2888045684 @default.
• W4288045153 hasRelatedWork W2974422904 @default.
• W4288045153 hasRelatedWork W3011191626 @default.
• W4288045153 hasRelatedWork W3213770797 @default.
• W4288045153 hasRelatedWork W2186662502 @default.
• W4288045153 hasVolume "39" @default.
• W4288045153 isParatext "false" @default.
• W4288045153 isRetracted "false" @default.

• next