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- W4288045252 abstract "• A novel dynamic intestinal model takes account of an enzyme secretion boundary. • The Se number is proposed to identify and quantify the secondary flow. • After a segmentation cycle of 2 s, the maximum mixing level reaches 41.8%. • The mixing level is increased by 76.0% at the highest viscosity of 5 Pa·s. • Shear strain rate (<220.4 s −1 ) in the system is suitable for enzymatic hydrolysis. High-solids enzymatic hydrolysis is a promising technology for biochemical conversion of lignocellulosic biomass. However, it may suffer from low efficiency in stirred-tank reactors due to poor mixing degree and enzyme deactivation by excessive shear rate. Inspired by the efficient mixing of viscous chyme and enzyme during intestinal motility, a biomimetic model with an enzyme secretion boundary was first proposed to explore the mixing enhancement mechanism. The dimensionless number Se m was established to characterize the secondary flow intensity. The results showed that increasing the segmentation amplitude to 66.7% improved Se m to 9.5 and the mixing level to 38.5%. Extension of the segmentation period resulted in the reduction of Se m , thus decreasing the mixing enhancement. The time-averaged mixing level was increased by 76.0% compared with the static tube at a substrate viscosity of 5.0 Pa·s. Furthermore, the shear strain rate was lower than 220.4 s −1 , which was conducive to maintaining enzyme activity." @default.
- W4288045252 created "2022-07-27" @default.
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- W4288045252 date "2022-10-01" @default.
- W4288045252 modified "2023-10-16" @default.
- W4288045252 title "Numerical investigation of bio-inspired mixing enhancement for enzymatic hydrolysis" @default.
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- W4288045252 doi "https://doi.org/10.1016/j.ces.2022.117950" @default.
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