Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288049282> ?p ?o ?g. }
- W4288049282 endingPage "802" @default.
- W4288049282 startingPage "791" @default.
- W4288049282 abstract "The present study aimed to explore the clinicopathological characteristics, potential heterogeneity and prognostic factors in synchronous bilateral breast cancer (SBBC).We performed a retrospective review and paired comparison of the clinicopathological characteristics of 114 patients with SBBC in the Peking Union Medical College Hospital from January 2008 to September 2019. The prognostic significance of triple negativity status and coexistence ductal carcinoma in situ (DCIS) with bilateral invasive ductal carcinomas of no special type (IDC-NST) was analyzed in SBBC.Most bilateral lesions on both sides were of IDC-NST, grade 2, luminal subtype, and stage I. Although most lesions were concordant between the left and right side, discordances were observed in histological type (25 cases, 21.9%), histological grade (31 cases, 27.2%), pTNM (61 cases, 53.5%), molecular subtypes (20 cases, 17.5%), and immunohistochemical staining of ER (18 cases, 15.8%), PR (26 cases, 22.8%), and HER2 (12 cases, 10.5%). Moreover, there was no significant difference in disease-free survival (DFS) and overall survival (OS) between IDC-NST with coexisting DCIS on both sides and IDC-NST with coexisting DCIS on one side or pure IDC-NST. SBBC with triple negativity on both sides exhibited a significantly shorter DFS and OS when compared with triple negativity on one side or non-triple negativity on both sides (p<0.001), and remained an independent prognostic factor by multivariate analysis.A considerable proportion of discordance in clinicopathological characteristics is observed in SBBC, supporting the necessity of comprehensive pathological examination including immunohistochemical testing on both sides in clinical practice. Moreover, SBBC with triple negativity on both sides is a prognostic for poor survival." @default.
- W4288049282 created "2022-07-27" @default.
- W4288049282 creator A5003036062 @default.
- W4288049282 creator A5013291809 @default.
- W4288049282 creator A5018129160 @default.
- W4288049282 creator A5033259499 @default.
- W4288049282 creator A5037677450 @default.
- W4288049282 creator A5054464310 @default.
- W4288049282 creator A5056500282 @default.
- W4288049282 creator A5075010118 @default.
- W4288049282 creator A5076543204 @default.
- W4288049282 date "2022-08-01" @default.
- W4288049282 modified "2023-09-30" @default.
- W4288049282 title "A comparative clinicopathological and survival analysis of synchronous bilateral breast cancers." @default.
- W4288049282 cites W111424356 @default.
- W4288049282 cites W1643840791 @default.
- W4288049282 cites W1845542724 @default.
- W4288049282 cites W1984329027 @default.
- W4288049282 cites W2009969222 @default.
- W4288049282 cites W2010588863 @default.
- W4288049282 cites W2013338017 @default.
- W4288049282 cites W2022736312 @default.
- W4288049282 cites W2023808432 @default.
- W4288049282 cites W2040907417 @default.
- W4288049282 cites W2042752971 @default.
- W4288049282 cites W2044342132 @default.
- W4288049282 cites W2057736095 @default.
- W4288049282 cites W2058871711 @default.
- W4288049282 cites W2080552686 @default.
- W4288049282 cites W2086762689 @default.
- W4288049282 cites W2096027508 @default.
- W4288049282 cites W2099305735 @default.
- W4288049282 cites W2130272541 @default.
- W4288049282 cites W2141925819 @default.
- W4288049282 cites W2144257911 @default.
- W4288049282 cites W2147221776 @default.
- W4288049282 cites W2151552902 @default.
- W4288049282 cites W2405614785 @default.
- W4288049282 cites W2585499135 @default.
- W4288049282 cites W2603868227 @default.
- W4288049282 cites W2809293192 @default.
- W4288049282 cites W2889646458 @default.
- W4288049282 cites W2914039479 @default.
- W4288049282 cites W2939656770 @default.
- W4288049282 cites W2942957278 @default.
- W4288049282 cites W2945531074 @default.
- W4288049282 cites W2959703621 @default.
- W4288049282 cites W2963846945 @default.
- W4288049282 cites W2963967924 @default.
- W4288049282 cites W2970355754 @default.
- W4288049282 cites W2976073313 @default.
- W4288049282 cites W2982655951 @default.
- W4288049282 cites W3006550589 @default.
- W4288049282 cites W3015524316 @default.
- W4288049282 cites W3093377140 @default.
- W4288049282 cites W3110381708 @default.
- W4288049282 cites W3136253269 @default.
- W4288049282 doi "https://doi.org/10.14670/hh-18-449" @default.
- W4288049282 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35285011" @default.
- W4288049282 hasPublicationYear "2022" @default.
- W4288049282 type Work @default.
- W4288049282 citedByCount "0" @default.
- W4288049282 crossrefType "journal-article" @default.
- W4288049282 hasAuthorship W4288049282A5003036062 @default.
- W4288049282 hasAuthorship W4288049282A5013291809 @default.
- W4288049282 hasAuthorship W4288049282A5018129160 @default.
- W4288049282 hasAuthorship W4288049282A5033259499 @default.
- W4288049282 hasAuthorship W4288049282A5037677450 @default.
- W4288049282 hasAuthorship W4288049282A5054464310 @default.
- W4288049282 hasAuthorship W4288049282A5056500282 @default.
- W4288049282 hasAuthorship W4288049282A5075010118 @default.
- W4288049282 hasAuthorship W4288049282A5076543204 @default.
- W4288049282 hasConcept C121608353 @default.
- W4288049282 hasConcept C126322002 @default.
- W4288049282 hasConcept C142724271 @default.
- W4288049282 hasConcept C143998085 @default.
- W4288049282 hasConcept C146357865 @default.
- W4288049282 hasConcept C151730666 @default.
- W4288049282 hasConcept C15744967 @default.
- W4288049282 hasConcept C204232928 @default.
- W4288049282 hasConcept C207886595 @default.
- W4288049282 hasConcept C2780110267 @default.
- W4288049282 hasConcept C2780862961 @default.
- W4288049282 hasConcept C3020375857 @default.
- W4288049282 hasConcept C38180746 @default.
- W4288049282 hasConcept C530470458 @default.
- W4288049282 hasConcept C71924100 @default.
- W4288049282 hasConcept C7453019 @default.
- W4288049282 hasConcept C77805123 @default.
- W4288049282 hasConcept C86803240 @default.
- W4288049282 hasConceptScore W4288049282C121608353 @default.
- W4288049282 hasConceptScore W4288049282C126322002 @default.
- W4288049282 hasConceptScore W4288049282C142724271 @default.
- W4288049282 hasConceptScore W4288049282C143998085 @default.
- W4288049282 hasConceptScore W4288049282C146357865 @default.
- W4288049282 hasConceptScore W4288049282C151730666 @default.
- W4288049282 hasConceptScore W4288049282C15744967 @default.
- W4288049282 hasConceptScore W4288049282C204232928 @default.