Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288049294> ?p ?o ?g. }
Showing items 1 to 55 of
55
with 100 items per page.
- W4288049294 abstract "Allergen immunotherapy is the only currently available treatment strategy that modifies the immune response to the causative allergen and induces clinical improvement and a steroid-sparing effect.In this real-life study, we aimed to evaluate and compare the efficacy of subcutaneous immunotherapy (SCIT) with one allergen or multiple allergens in children and adults with asthma and/or allergic rhinitis in terms of disease control and a steroid-sparing effect.Demographics, the initial inhaled corticosteroid (ICS) and/or intranasal corticosteroid (INS) dose, and other drugs of patients receiving SCIT for at least 12 months were recorded. Data on the final dose/use of ICS/INS and asthma and/or allergic rhinitis control were gathered.Of 104 patients included, 57.1% and 64.5% of patients with asthma and allergic rhinitis, respectively, were able to discontinue ICS and INS after SCIT. The median time to INS and ICS dose reduction was 6 months. SCIT with one allergen or multiple allergens effectively reduced the ICS and INS dose and led to control of asthma and allergic rhinitis, with no significant difference between the groups. When the efficacy of SCIT was compared in children and adults, there was no significant difference in terms of a steroid-sparing effect or the control of asthma and allergic rhinitis. SCIT was effective in both children and adult patients.In this real-life observational study, we have demonstrated a marked steroid-sparing effect while maintaining control of asthma and allergic rhinitis in children and adults treated with one allergen or multiple allergens." @default.
- W4288049294 created "2022-07-27" @default.
- W4288049294 creator A5017183785 @default.
- W4288049294 creator A5037205316 @default.
- W4288049294 creator A5052932506 @default.
- W4288049294 date "2022-03-12" @default.
- W4288049294 modified "2023-09-29" @default.
- W4288049294 title "Maintained disease control and steroid-sparing effect of subcutaneous immunotherapy in allergic rhinitis and asthma." @default.
- W4288049294 doi "https://doi.org/10.12932/ap-030921-1222" @default.
- W4288049294 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35278058" @default.
- W4288049294 hasPublicationYear "2022" @default.
- W4288049294 type Work @default.
- W4288049294 citedByCount "0" @default.
- W4288049294 crossrefType "journal-article" @default.
- W4288049294 hasAuthorship W4288049294A5017183785 @default.
- W4288049294 hasAuthorship W4288049294A5037205316 @default.
- W4288049294 hasAuthorship W4288049294A5052932506 @default.
- W4288049294 hasConcept C126322002 @default.
- W4288049294 hasConcept C203014093 @default.
- W4288049294 hasConcept C207480886 @default.
- W4288049294 hasConcept C2776042228 @default.
- W4288049294 hasConcept C2776804153 @default.
- W4288049294 hasConcept C2777701055 @default.
- W4288049294 hasConcept C2779787640 @default.
- W4288049294 hasConcept C2780510475 @default.
- W4288049294 hasConcept C71924100 @default.
- W4288049294 hasConcept C85663871 @default.
- W4288049294 hasConcept C8891405 @default.
- W4288049294 hasConceptScore W4288049294C126322002 @default.
- W4288049294 hasConceptScore W4288049294C203014093 @default.
- W4288049294 hasConceptScore W4288049294C207480886 @default.
- W4288049294 hasConceptScore W4288049294C2776042228 @default.
- W4288049294 hasConceptScore W4288049294C2776804153 @default.
- W4288049294 hasConceptScore W4288049294C2777701055 @default.
- W4288049294 hasConceptScore W4288049294C2779787640 @default.
- W4288049294 hasConceptScore W4288049294C2780510475 @default.
- W4288049294 hasConceptScore W4288049294C71924100 @default.
- W4288049294 hasConceptScore W4288049294C85663871 @default.
- W4288049294 hasConceptScore W4288049294C8891405 @default.
- W4288049294 hasLocation W42880492941 @default.
- W4288049294 hasOpenAccess W4288049294 @default.
- W4288049294 hasPrimaryLocation W42880492941 @default.
- W4288049294 hasRelatedWork W10658642 @default.
- W4288049294 hasRelatedWork W14547262 @default.
- W4288049294 hasRelatedWork W16230605 @default.
- W4288049294 hasRelatedWork W16274969 @default.
- W4288049294 hasRelatedWork W19065172 @default.
- W4288049294 hasRelatedWork W2316060 @default.
- W4288049294 hasRelatedWork W347278 @default.
- W4288049294 hasRelatedWork W525198 @default.
- W4288049294 hasRelatedWork W553467 @default.
- W4288049294 hasRelatedWork W167555 @default.
- W4288049294 isParatext "false" @default.
- W4288049294 isRetracted "false" @default.
- W4288049294 workType "article" @default.