Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288049305> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W4288049305 endingPage "e2021239" @default.
- W4288049305 startingPage "e2021239" @default.
- W4288049305 abstract "Hashimoto's thyroiditis (HT) is a common endocrinopathy in children, particularly in females. Clinical overt presentation of hypothyroidism in HT includes mild to very severe forms, characterised by impairment of many body functions and organs, such as heart, brain, muscles, ovaries and liver.we report the case of a 14-year-old girl, with severe hypothyroidism due to a late diagnosis of HT during the Covid-19 pandemic. Routine biochemical and hormonal exams were carried out at presentation. Moderate pericardial effusion was detected by echocardiography and polycystic ovarian morphology (PCOM) was found on the pelvic ultrasound. Furthermore, high levels of creatine phosphokinase (CPK), Lactic Acid Dehydrogenase (LDH) and hepatic liver enzymes, associated with muscular pseudohypertrophy and bilateral weakness of the lower limbs, were suggestive of a rare presentation of long-standing hypothyroidism defined Kocher-Debre-Semelaigne syndrome (KDSS). Levothyroxine replacement therapy was started immediately, leading to a rapid improvement of symptoms and a progressive normalization of the biochemical parameters. Due to persistent lower limb weakness, further neurological investigations were performed, showing bilateral peripheral polyneuropathy (PNP), ascribable to the longstanding and severe hypothyroidism. A pelvic ultrasound, performed after thyroid hormones had normalised and menses had turned to be regular, showed normal ovarian features supporting the hypothesis of the Van Wyk and Grumbach syndrome in a post-menarcheal girl.although clinical manifestation of hypothyroidism are usually mild, more severe and rare presentations such as ovarian dysfunction and myopathy are possible, particularly if the diagnosis is delayed and replacement therapy is not promptly administered." @default.
- W4288049305 created "2022-07-27" @default.
- W4288049305 creator A5000867450 @default.
- W4288049305 creator A5028640859 @default.
- W4288049305 creator A5036009201 @default.
- W4288049305 creator A5037186932 @default.
- W4288049305 creator A5040161808 @default.
- W4288049305 creator A5042868297 @default.
- W4288049305 creator A5046206108 @default.
- W4288049305 creator A5049875681 @default.
- W4288049305 creator A5058095534 @default.
- W4288049305 creator A5075683382 @default.
- W4288049305 creator A5076413784 @default.
- W4288049305 date "2022-03-08" @default.
- W4288049305 modified "2023-10-17" @default.
- W4288049305 title "Late diagnosis of severe long-standing autoimmune hypothyroidism after the first lockdown for the Covid-19 pandemic: clinical features and follow-up." @default.
- W4288049305 cites W1545261941 @default.
- W4288049305 cites W1968081664 @default.
- W4288049305 cites W1975428722 @default.
- W4288049305 cites W2012466439 @default.
- W4288049305 cites W2022832067 @default.
- W4288049305 cites W2034362112 @default.
- W4288049305 cites W2054183178 @default.
- W4288049305 cites W2115640067 @default.
- W4288049305 cites W2160234571 @default.
- W4288049305 cites W2162925752 @default.
- W4288049305 cites W2171705785 @default.
- W4288049305 cites W2326818328 @default.
- W4288049305 cites W2419247392 @default.
- W4288049305 cites W2441658309 @default.
- W4288049305 cites W2584204775 @default.
- W4288049305 cites W2607031541 @default.
- W4288049305 cites W2774914183 @default.
- W4288049305 cites W2806629973 @default.
- W4288049305 cites W2896375055 @default.
- W4288049305 cites W2913115055 @default.
- W4288049305 cites W2915153716 @default.
- W4288049305 cites W2967645434 @default.
- W4288049305 cites W3060397322 @default.
- W4288049305 doi "https://doi.org/10.23750/abm.v92is1.11730" @default.
- W4288049305 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35261392" @default.
- W4288049305 hasPublicationYear "2022" @default.
- W4288049305 type Work @default.
- W4288049305 citedByCount "0" @default.
- W4288049305 crossrefType "journal-article" @default.
- W4288049305 hasAuthorship W4288049305A5000867450 @default.
- W4288049305 hasAuthorship W4288049305A5028640859 @default.
- W4288049305 hasAuthorship W4288049305A5036009201 @default.
- W4288049305 hasAuthorship W4288049305A5037186932 @default.
- W4288049305 hasAuthorship W4288049305A5040161808 @default.
- W4288049305 hasAuthorship W4288049305A5042868297 @default.
- W4288049305 hasAuthorship W4288049305A5046206108 @default.
- W4288049305 hasAuthorship W4288049305A5049875681 @default.
- W4288049305 hasAuthorship W4288049305A5058095534 @default.
- W4288049305 hasAuthorship W4288049305A5075683382 @default.
- W4288049305 hasAuthorship W4288049305A5076413784 @default.
- W4288049305 hasConcept C126322002 @default.
- W4288049305 hasConcept C141071460 @default.
- W4288049305 hasConcept C187212893 @default.
- W4288049305 hasConcept C2775883008 @default.
- W4288049305 hasConcept C2777300911 @default.
- W4288049305 hasConcept C2780247198 @default.
- W4288049305 hasConcept C2780302416 @default.
- W4288049305 hasConcept C2780597408 @default.
- W4288049305 hasConcept C2781175549 @default.
- W4288049305 hasConcept C526584372 @default.
- W4288049305 hasConcept C71924100 @default.
- W4288049305 hasConcept C90924648 @default.
- W4288049305 hasConceptScore W4288049305C126322002 @default.
- W4288049305 hasConceptScore W4288049305C141071460 @default.
- W4288049305 hasConceptScore W4288049305C187212893 @default.
- W4288049305 hasConceptScore W4288049305C2775883008 @default.
- W4288049305 hasConceptScore W4288049305C2777300911 @default.
- W4288049305 hasConceptScore W4288049305C2780247198 @default.
- W4288049305 hasConceptScore W4288049305C2780302416 @default.
- W4288049305 hasConceptScore W4288049305C2780597408 @default.
- W4288049305 hasConceptScore W4288049305C2781175549 @default.
- W4288049305 hasConceptScore W4288049305C526584372 @default.
- W4288049305 hasConceptScore W4288049305C71924100 @default.
- W4288049305 hasConceptScore W4288049305C90924648 @default.
- W4288049305 hasIssue "S1" @default.
- W4288049305 hasLocation W42880493051 @default.
- W4288049305 hasOpenAccess W4288049305 @default.
- W4288049305 hasPrimaryLocation W42880493051 @default.
- W4288049305 hasRelatedWork W2092286633 @default.
- W4288049305 hasRelatedWork W2261628748 @default.
- W4288049305 hasRelatedWork W2357012018 @default.
- W4288049305 hasRelatedWork W2618254838 @default.
- W4288049305 hasRelatedWork W2748952813 @default.
- W4288049305 hasRelatedWork W3133762537 @default.
- W4288049305 hasRelatedWork W3158482145 @default.
- W4288049305 hasRelatedWork W4381197018 @default.
- W4288049305 hasRelatedWork W2151796003 @default.
- W4288049305 hasRelatedWork W2291276304 @default.
- W4288049305 hasVolume "92" @default.
- W4288049305 isParatext "false" @default.
- W4288049305 isRetracted "false" @default.
- W4288049305 workType "article" @default.