Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288049365> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W4288049365 endingPage "50" @default.
- W4288049365 startingPage "40" @default.
- W4288049365 abstract "Despite topical fluoride being used for over 50 years in caries prevention, its complete potential in terms of formation of fluorapatite enamel and prolonged surface retention has not been harnessed.This study aimed to assess the effectiveness of nanoparticle based acidulated phosphate fluoride (APF) gel on surface enamel fluoride uptake through split mouth design over a period of six months, on patients undergoing orthodontic treatment and indicated for bilateral extraction of premolars on at least one of the arch.A split mouth non randomized clinical trial was performed. Each of the 30 participants received one application of 4 minutes duration of both the intervention: Right half of the mouth received nanoparticle based APF gel, and left half of the mouth received conventional APF gel (16 Oz Pascal Corp.; strawberry flavor). Bilateral acid etch biopsy of enamel surface was take at 3 intervals- baseline,24 hours and 30 days. Using 1ml of 0.5M perchloric acid, acid etch enamel biopsy was taken for all the study subjects at 3 intervals of time (baseline, 24 hours and 30 days), bilaterally on the buccal and palatal/lingual surface of maxillary or mandibular premolars indicated for extraction, using 1 (l of 0.5M perchloric acid. After the premolars were extracted, scanning electron microscope (SEM) analysis was done to determine the surface characteristics of enamel in both groups.Overall, both fluoride uptake and depth of biopsy remained significant even after controlling for the covariates (time, group) individually and simultaneously (p< 0.05). Further analysis showed that fluoride uptake was significantly increased and biopsy depth significantly decreased in the nanoparticle based APF gel group at 24 hour and 30 day evaluation respectively.By reducing the size of sodium fluoride to increase the surface enamel uptake, our results support the use of this top down approach as a promising strategy for effective delivery of topical fluorides. This highlights that the top down approach of nanoscience to reduce the size active compound sodium fluoride has increased the uptake and retention of surface enamel fluoride." @default.
- W4288049365 created "2022-07-27" @default.
- W4288049365 creator A5031377464 @default.
- W4288049365 creator A5068313798 @default.
- W4288049365 creator A5070272038 @default.
- W4288049365 date "2022-03-01" @default.
- W4288049365 modified "2023-09-29" @default.
- W4288049365 title "Effectiveness of Nanoparticle-Based Acidulated Phosphate Fluoride (APF) Gel on Surface Enamel Fluoride Uptake: an Interventional Study." @default.
- W4288049365 cites W136416290 @default.
- W4288049365 cites W1513381463 @default.
- W4288049365 cites W1514902974 @default.
- W4288049365 cites W1574576475 @default.
- W4288049365 cites W1764136307 @default.
- W4288049365 cites W1944431556 @default.
- W4288049365 cites W1962423111 @default.
- W4288049365 cites W1968104496 @default.
- W4288049365 cites W1983069463 @default.
- W4288049365 cites W1985342632 @default.
- W4288049365 cites W1997081293 @default.
- W4288049365 cites W2015855766 @default.
- W4288049365 cites W2029822400 @default.
- W4288049365 cites W2036660099 @default.
- W4288049365 cites W2058695745 @default.
- W4288049365 cites W2074746616 @default.
- W4288049365 cites W2087797495 @default.
- W4288049365 cites W2130149377 @default.
- W4288049365 cites W2136626017 @default.
- W4288049365 cites W2137112474 @default.
- W4288049365 cites W2170218633 @default.
- W4288049365 cites W2260564770 @default.
- W4288049365 cites W2264856079 @default.
- W4288049365 cites W2418828343 @default.
- W4288049365 cites W2760213365 @default.
- W4288049365 doi "https://doi.org/10.30476/dentjods.2021.87895.1295" @default.
- W4288049365 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35291680" @default.
- W4288049365 hasPublicationYear "2022" @default.
- W4288049365 type Work @default.
- W4288049365 citedByCount "0" @default.
- W4288049365 crossrefType "journal-article" @default.
- W4288049365 hasAuthorship W4288049365A5031377464 @default.
- W4288049365 hasAuthorship W4288049365A5068313798 @default.
- W4288049365 hasAuthorship W4288049365A5070272038 @default.
- W4288049365 hasConcept C13965031 @default.
- W4288049365 hasConcept C156887251 @default.
- W4288049365 hasConcept C179104552 @default.
- W4288049365 hasConcept C185592680 @default.
- W4288049365 hasConcept C199289684 @default.
- W4288049365 hasConcept C199343813 @default.
- W4288049365 hasConcept C202271784 @default.
- W4288049365 hasConcept C2777746296 @default.
- W4288049365 hasConcept C2778161354 @default.
- W4288049365 hasConcept C2780641865 @default.
- W4288049365 hasConcept C2780828025 @default.
- W4288049365 hasConcept C3025077 @default.
- W4288049365 hasConcept C71924100 @default.
- W4288049365 hasConceptScore W4288049365C13965031 @default.
- W4288049365 hasConceptScore W4288049365C156887251 @default.
- W4288049365 hasConceptScore W4288049365C179104552 @default.
- W4288049365 hasConceptScore W4288049365C185592680 @default.
- W4288049365 hasConceptScore W4288049365C199289684 @default.
- W4288049365 hasConceptScore W4288049365C199343813 @default.
- W4288049365 hasConceptScore W4288049365C202271784 @default.
- W4288049365 hasConceptScore W4288049365C2777746296 @default.
- W4288049365 hasConceptScore W4288049365C2778161354 @default.
- W4288049365 hasConceptScore W4288049365C2780641865 @default.
- W4288049365 hasConceptScore W4288049365C2780828025 @default.
- W4288049365 hasConceptScore W4288049365C3025077 @default.
- W4288049365 hasConceptScore W4288049365C71924100 @default.
- W4288049365 hasIssue "1" @default.
- W4288049365 hasLocation W42880493651 @default.
- W4288049365 hasOpenAccess W4288049365 @default.
- W4288049365 hasPrimaryLocation W42880493651 @default.
- W4288049365 hasRelatedWork W11020097 @default.
- W4288049365 hasRelatedWork W1261985 @default.
- W4288049365 hasRelatedWork W2689643 @default.
- W4288049365 hasRelatedWork W3829468 @default.
- W4288049365 hasRelatedWork W4036938 @default.
- W4288049365 hasRelatedWork W5178588 @default.
- W4288049365 hasRelatedWork W6355527 @default.
- W4288049365 hasRelatedWork W6785653 @default.
- W4288049365 hasRelatedWork W9089770 @default.
- W4288049365 hasRelatedWork W922063 @default.
- W4288049365 hasVolume "23" @default.
- W4288049365 isParatext "false" @default.
- W4288049365 isRetracted "false" @default.
- W4288049365 workType "article" @default.