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• W4288049678 abstract "How can a collection of motile cells, each generating contractile nematic stresses in isolation, become an extensile nematic at the tissue level? Understanding this seemingly contradictory experimental observation, which occurs irrespective of whether the tissue is in the liquid or solid states, is not only crucial to our understanding of diverse biological processes, but is also of fundamental interest to soft matter and many-body physics. Here, we resolve this cellular to tissue level disconnect in the small fluctuation regime by using analytical theories based on hydrodynamic descriptions of confluent tissues, in both liquid and solid states. Specifically, we show that a collection of microscopic constituents with no inherently nematic extensile forces can exhibit active extensile nematic behavior when subject to polar fluctuating forces. We further support our findings by performing cell level simulations of minimal models of confluent tissues." @default.
• W4288049678 created "2022-07-27" @default.
• W4288049678 creator A5053720454 @default.
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• W4288049678 date "2022-02-15" @default.
• W4288049678 modified "2023-09-26" @default.
• W4288049678 title "Polar Fluctuations Lead to Extensile Nematic Behavior in Confluent Tissues" @default.
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• W4288049678 doi "https://doi.org/10.1103/physrevlett.128.078001" @default.
• W4288049678 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35244433" @default.
• W4288049678 hasPublicationYear "2022" @default.
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