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- W4288049812 abstract "Optogenetics, a technology to manipulate biological phenomena thorough light, has attracted much attention in neuroscience. Recently, the Magnet System, a photo-inducible protein dimerization system which can control the intracellular behavior of various biomolecules with high accuracy using light was developed. Furthermore, photoactivation systems for controlling biological phenomena are being developed by combining this technique with genome-editing technology (CRISPR/Cas9 System) or DNA recombination technology (Cre-loxP system). Herein, we review the history of optogenetics and the latest Magnet System technology and introduce our recently developed photoactivatable Cre knock-in mice with temporal-, spatial-, and cell-specific accuracy." @default.
- W4288049812 created "2022-07-27" @default.
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- W4288049812 date "2022-02-01" @default.
- W4288049812 modified "2023-09-29" @default.
- W4288049812 title "Mouse Model for Optogenetic Genome Engineering." @default.
- W4288049812 doi "https://doi.org/10.18926/amo/63202" @default.
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