Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288051561> ?p ?o ?g. }
- W4288051561 endingPage "27689" @default.
- W4288051561 startingPage "27674" @default.
- W4288051561 abstract "An efficient and environmentally friendly method was established for designing novel 3-amino-1,4-dihydroquinoxaline-2-carbonitrile (1) via the reaction of bromomalononitrile and benzene-1,2-diamine under microwave irradiation in an excellent yield (93%). This targeted amino derivative was utilized for the construction of a series of Schiff bases (8-13). A new series of thiazolidinone derivatives (15-20) were synthesized in high yields (89-96%) via treatment of thioglycolic acid with Schiff bases (8-13) under microwave irradiation in high yields (89-96%). Moreover, new pyrimidine derivatives (26-30 and 35-38) were prepared by treatment of compound 1 with arylidenes (21-25) and/or alkylidenemalononitriles (31-34) using piperidine as a basic catalyst under microwave conditions. Based on elemental analyses and spectral data, the structures of the new assembled compounds were determined. The newly synthesized quinoxaline derivatives were screened and studied as an insecticidal agent against Aphis craccivora. The obtained results indicate that compound 16 is the most toxicological agent against nymphs of cowpea aphids (Aphis craccivora) compared to the other synthesized pyrimidine and thiazolidinone derivatives. The molecular docking study of the new quinoxaline derivatives registered that compound 16 had the highest binding score (-10.54 kcal/mol) and the thiazolidinone moiety formed hydrogen bonds with Trp143." @default.
- W4288051561 created "2022-07-28" @default.
- W4288051561 creator A5001687040 @default.
- W4288051561 creator A5005307683 @default.
- W4288051561 creator A5009530307 @default.
- W4288051561 creator A5013522892 @default.
- W4288051561 creator A5025180828 @default.
- W4288051561 creator A5050073895 @default.
- W4288051561 date "2022-07-27" @default.
- W4288051561 modified "2023-09-26" @default.
- W4288051561 title "Green Design, Synthesis, and Molecular Docking Study of Novel Quinoxaline Derivatives with Insecticidal Potential against <i>Aphis craccivora</i>" @default.
- W4288051561 cites W1519144515 @default.
- W4288051561 cites W1566219075 @default.
- W4288051561 cites W1903705656 @default.
- W4288051561 cites W1968884389 @default.
- W4288051561 cites W1972884884 @default.
- W4288051561 cites W1991716701 @default.
- W4288051561 cites W1995716106 @default.
- W4288051561 cites W1997014318 @default.
- W4288051561 cites W2012195291 @default.
- W4288051561 cites W2023667091 @default.
- W4288051561 cites W2038841540 @default.
- W4288051561 cites W2063156431 @default.
- W4288051561 cites W2078614198 @default.
- W4288051561 cites W2095536623 @default.
- W4288051561 cites W2099231947 @default.
- W4288051561 cites W2114718388 @default.
- W4288051561 cites W2118063127 @default.
- W4288051561 cites W2123036062 @default.
- W4288051561 cites W2126760605 @default.
- W4288051561 cites W2154720983 @default.
- W4288051561 cites W2155118851 @default.
- W4288051561 cites W2231061689 @default.
- W4288051561 cites W2315490627 @default.
- W4288051561 cites W2316776483 @default.
- W4288051561 cites W2346996915 @default.
- W4288051561 cites W2460204863 @default.
- W4288051561 cites W2496741404 @default.
- W4288051561 cites W2505400006 @default.
- W4288051561 cites W2519761872 @default.
- W4288051561 cites W2550797142 @default.
- W4288051561 cites W2551474508 @default.
- W4288051561 cites W2558700501 @default.
- W4288051561 cites W2591101786 @default.
- W4288051561 cites W2594780853 @default.
- W4288051561 cites W2614843426 @default.
- W4288051561 cites W2751480182 @default.
- W4288051561 cites W2771006473 @default.
- W4288051561 cites W2771052762 @default.
- W4288051561 cites W2775069015 @default.
- W4288051561 cites W2781831436 @default.
- W4288051561 cites W2790938954 @default.
- W4288051561 cites W2791414130 @default.
- W4288051561 cites W2792578312 @default.
- W4288051561 cites W2795906125 @default.
- W4288051561 cites W2889317738 @default.
- W4288051561 cites W2900822198 @default.
- W4288051561 cites W2905806466 @default.
- W4288051561 cites W2915841415 @default.
- W4288051561 cites W2916599758 @default.
- W4288051561 cites W2943503365 @default.
- W4288051561 cites W2970637801 @default.
- W4288051561 cites W2985776886 @default.
- W4288051561 cites W2991685002 @default.
- W4288051561 cites W2994805154 @default.
- W4288051561 cites W2999836262 @default.
- W4288051561 cites W3005710086 @default.
- W4288051561 cites W3011131279 @default.
- W4288051561 cites W3025478603 @default.
- W4288051561 cites W3035449432 @default.
- W4288051561 cites W3046300696 @default.
- W4288051561 cites W3086149183 @default.
- W4288051561 cites W3093694880 @default.
- W4288051561 cites W3120270748 @default.
- W4288051561 cites W3131418608 @default.
- W4288051561 cites W3152638283 @default.
- W4288051561 cites W3164883414 @default.
- W4288051561 cites W3170423241 @default.
- W4288051561 cites W3174769610 @default.
- W4288051561 cites W3180233625 @default.
- W4288051561 cites W3180554220 @default.
- W4288051561 cites W3196457549 @default.
- W4288051561 cites W3213020936 @default.
- W4288051561 cites W4200294595 @default.
- W4288051561 cites W4206376273 @default.
- W4288051561 cites W4207023459 @default.
- W4288051561 cites W4210424925 @default.
- W4288051561 cites W4210854720 @default.
- W4288051561 cites W4212860366 @default.
- W4288051561 cites W4214524129 @default.
- W4288051561 cites W4220685544 @default.
- W4288051561 cites W4221093779 @default.
- W4288051561 cites W4223898701 @default.
- W4288051561 cites W4224211190 @default.
- W4288051561 cites W4226085871 @default.
- W4288051561 cites W4251887477 @default.
- W4288051561 cites W4252526273 @default.
- W4288051561 cites W4281623828 @default.