Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288059244> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W4288059244 endingPage "34" @default.
- W4288059244 startingPage "27" @default.
- W4288059244 abstract "Fungal otitis extern or otomycosis, is common worldwide, and resistance of fungal organisms to antifungal drugs has been reported in otomycosis and other fungal infections. This study aimed to evaluate the clinical efficacy of sertaconazole versus placebo, as well as miconazole and clotrimazole topical creams in otomycosis patients.In this double-blinded clinical trial, 138 otomycosis patients (230 ears) were evaluated in four groups. After the first session of the ear canal debridement and irrigation with acetic acid 2% solution, the patients were treated with either A) sertaconazole 2% cream, B) miconazole 2% cream, C) clotrimazole 2% cream, or D) placebo. The results of clinical evaluations and response to treatment (complete, partial, and no response) were recorded at the time of the first visit and by the end of the first, second, and fourth weeks of treatment. A p-value less than 0.05 was considered statistically significant.Response results to treatments, ear itching, aural fullness, otalgia, and otorrhea revealed significant differences in either group A or groups B and C, compared to the placebo group (P<0.05). Considering both complete and partial responses together, the sertaconazole group showed a 96.43% response rate. For complete response, miconazole revealed better results, compared to the other two creams; however, the differences for the therapeutic outcomes were not statistically significant. No adverse reactions were observed in the study groups.Sertaconazole had comparable results with miconazole and clotrimazole in the treatment of otomycosis, and especially if complete and partial responses were considered together, it was more efficacious than miconazole and clotrimazole creams." @default.
- W4288059244 created "2022-07-28" @default.
- W4288059244 creator A5005144675 @default.
- W4288059244 creator A5008928424 @default.
- W4288059244 creator A5014403579 @default.
- W4288059244 creator A5020340828 @default.
- W4288059244 creator A5020822115 @default.
- W4288059244 creator A5033777658 @default.
- W4288059244 creator A5052452871 @default.
- W4288059244 date "2022-01-01" @default.
- W4288059244 modified "2023-10-17" @default.
- W4288059244 title "Sertaconazole versus Clotrimazole and Miconazole Creams in the Treatment of Otomycosis: A Placebo-Controlled Clinical Trial." @default.
- W4288059244 cites W1969415603 @default.
- W4288059244 cites W1976824742 @default.
- W4288059244 cites W2035054483 @default.
- W4288059244 cites W2044863379 @default.
- W4288059244 cites W2046549672 @default.
- W4288059244 cites W2054190388 @default.
- W4288059244 cites W2141261344 @default.
- W4288059244 cites W2143919231 @default.
- W4288059244 cites W2158069073 @default.
- W4288059244 cites W2408888420 @default.
- W4288059244 cites W3004836296 @default.
- W4288059244 cites W2124916251 @default.
- W4288059244 doi "https://doi.org/10.22038/ijorl.2021.54805.2872" @default.
- W4288059244 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35145933" @default.
- W4288059244 hasPublicationYear "2022" @default.
- W4288059244 type Work @default.
- W4288059244 citedByCount "1" @default.
- W4288059244 countsByYear W42880592442023 @default.
- W4288059244 crossrefType "journal-article" @default.
- W4288059244 hasAuthorship W4288059244A5005144675 @default.
- W4288059244 hasAuthorship W4288059244A5008928424 @default.
- W4288059244 hasAuthorship W4288059244A5014403579 @default.
- W4288059244 hasAuthorship W4288059244A5020340828 @default.
- W4288059244 hasAuthorship W4288059244A5020822115 @default.
- W4288059244 hasAuthorship W4288059244A5033777658 @default.
- W4288059244 hasAuthorship W4288059244A5052452871 @default.
- W4288059244 hasConcept C141071460 @default.
- W4288059244 hasConcept C142724271 @default.
- W4288059244 hasConcept C16005928 @default.
- W4288059244 hasConcept C204787440 @default.
- W4288059244 hasConcept C27081682 @default.
- W4288059244 hasConcept C2776439223 @default.
- W4288059244 hasConcept C2777220567 @default.
- W4288059244 hasConcept C2777229883 @default.
- W4288059244 hasConcept C2779548794 @default.
- W4288059244 hasConcept C2780628323 @default.
- W4288059244 hasConcept C42219234 @default.
- W4288059244 hasConcept C71924100 @default.
- W4288059244 hasConceptScore W4288059244C141071460 @default.
- W4288059244 hasConceptScore W4288059244C142724271 @default.
- W4288059244 hasConceptScore W4288059244C16005928 @default.
- W4288059244 hasConceptScore W4288059244C204787440 @default.
- W4288059244 hasConceptScore W4288059244C27081682 @default.
- W4288059244 hasConceptScore W4288059244C2776439223 @default.
- W4288059244 hasConceptScore W4288059244C2777220567 @default.
- W4288059244 hasConceptScore W4288059244C2777229883 @default.
- W4288059244 hasConceptScore W4288059244C2779548794 @default.
- W4288059244 hasConceptScore W4288059244C2780628323 @default.
- W4288059244 hasConceptScore W4288059244C42219234 @default.
- W4288059244 hasConceptScore W4288059244C71924100 @default.
- W4288059244 hasIssue "120" @default.
- W4288059244 hasLocation W42880592441 @default.
- W4288059244 hasLocation W42880592442 @default.
- W4288059244 hasOpenAccess W4288059244 @default.
- W4288059244 hasPrimaryLocation W42880592441 @default.
- W4288059244 hasRelatedWork W13960275 @default.
- W4288059244 hasRelatedWork W1428282 @default.
- W4288059244 hasRelatedWork W15501536 @default.
- W4288059244 hasRelatedWork W19849351 @default.
- W4288059244 hasRelatedWork W20921961 @default.
- W4288059244 hasRelatedWork W4013065 @default.
- W4288059244 hasRelatedWork W527582 @default.
- W4288059244 hasRelatedWork W8129469 @default.
- W4288059244 hasRelatedWork W844564 @default.
- W4288059244 hasRelatedWork W6836849 @default.
- W4288059244 hasVolume "34" @default.
- W4288059244 isParatext "false" @default.
- W4288059244 isRetracted "false" @default.
- W4288059244 workType "article" @default.