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- W4288059660 abstract "Blood coagulation is a critical element of host defense. The ability of blood to clot when a vessel has been damaged, yet to keep that clot localized to the site of injury, is a tenuous challenge that is required for maintenance of hemostasis. The balance between hemostasis, hemorrhage and thrombosis is achieved by the tight regulation of pro-coagulant and anti-coagulant proteins/cofactors, platelets and the blood vessel surface. The focus of this article is an overview of hemostasis, primary (platelets and endothelial cells) and secondary (plasma-derived coagulation factors), and fibrinolysis. The most common acquired and inherited coagulation disorders are also described." @default.
- W4288059660 created "2022-07-28" @default.
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- W4288059660 date "2023-01-01" @default.
- W4288059660 modified "2023-09-27" @default.
- W4288059660 title "Overview of Blood Coagulation and the Pathophysiology of Blood Coagulation Disorders" @default.
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- W4288059660 doi "https://doi.org/10.1016/b978-0-12-821618-7.00160-7" @default.
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