Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288060276> ?p ?o ?g. }
Showing items 1 to 64 of
64
with 100 items per page.
- W4288060276 abstract "Background: Stress exposure contributes to the onset, maintenance, and recurrence of Major Depressive Disorder (MDD) in adolescents. However, the precise stress facets (e.g., chronicity, domain) most strongly linked to outcomes at different stages along the depression severity continuum remain unclear. Across two studies, chronic and episodic stressors were comprehensively assessed among: (a) healthy youth with (High-Risk [HR]) and without (Low-Risk [LR]) a maternal history of MDD and (b) adolescents with current MDD and suicide ideation and healthy controls (HC). Method: Study 1 included LR (n=65) and HR (n=22) 12- to 14-year-olds (49 females; 56.32%) with no lifetime history of mental disorders. Study 2 enrolled 87 mid-to-late adolescents (64 females; 73.56%), including 57 MDD youth from a short-term intensive treatment service and 30 HCs from the community. All depressed youth reported recent suicide ideation; some had no lifetime history suicide attempts (SI; n=31) and others reported at least one past year attempt (SA; n=26). The Life Events and Difficulties Schedule was used to capture stressor severity in both studies. Results: We used multiple linear regression models that adjusted for demographic and clinical covariates. Being in the HR versus LR group was associated with more severe chronic (β=0.22, CI95=0.01-0.42, p=0.041), independent (β=0.34, CI95=0.12-0.56, p=0.003) and interpersonal (β=0.23, CI95=0.004-0.45, p=0.047) stress severity. By contrast, being in the MDD versus HC group was associated with chronic (β=0.62, CI95=0.45-0.79, p<0.001) and dependent (β=0.41, CI95=0.21-0.61, p<0.001), but not independent (p=0.083), stress. Stress severity was not associated with suicide attempts in youth experiencing ideation (SA versus SI contrast). However, the SA group reported a significantly higher rate of targeted rejection events (RR=3.29, CI95=1.07-10.10, p=0.037); these preliminary findings warrant replication in larger samples. Conclusion: Findings suggest the stressor features that most strongly contribute to adolescent depression and its clinical correlates may shift over its clinical course." @default.
- W4288060276 created "2022-07-28" @default.
- W4288060276 creator A5071174795 @default.
- W4288060276 creator A5085974762 @default.
- W4288060276 creator A5091015762 @default.
- W4288060276 date "2022-07-28" @default.
- W4288060276 modified "2023-09-28" @default.
- W4288060276 title "Stress exposure in at-risk, depressed, and suicidal adolescents" @default.
- W4288060276 doi "https://doi.org/10.31234/osf.io/he7wf" @default.
- W4288060276 hasPublicationYear "2022" @default.
- W4288060276 type Work @default.
- W4288060276 citedByCount "0" @default.
- W4288060276 crossrefType "posted-content" @default.
- W4288060276 hasAuthorship W4288060276A5071174795 @default.
- W4288060276 hasAuthorship W4288060276A5085974762 @default.
- W4288060276 hasAuthorship W4288060276A5091015762 @default.
- W4288060276 hasBestOaLocation W42880602761 @default.
- W4288060276 hasConcept C118552586 @default.
- W4288060276 hasConcept C125370674 @default.
- W4288060276 hasConcept C126322002 @default.
- W4288060276 hasConcept C139719470 @default.
- W4288060276 hasConcept C15744967 @default.
- W4288060276 hasConcept C162324750 @default.
- W4288060276 hasConcept C190385971 @default.
- W4288060276 hasConcept C2776641880 @default.
- W4288060276 hasConcept C2776867660 @default.
- W4288060276 hasConcept C2780051608 @default.
- W4288060276 hasConcept C2780733359 @default.
- W4288060276 hasConcept C3017944768 @default.
- W4288060276 hasConcept C70410870 @default.
- W4288060276 hasConcept C71924100 @default.
- W4288060276 hasConcept C99454951 @default.
- W4288060276 hasConceptScore W4288060276C118552586 @default.
- W4288060276 hasConceptScore W4288060276C125370674 @default.
- W4288060276 hasConceptScore W4288060276C126322002 @default.
- W4288060276 hasConceptScore W4288060276C139719470 @default.
- W4288060276 hasConceptScore W4288060276C15744967 @default.
- W4288060276 hasConceptScore W4288060276C162324750 @default.
- W4288060276 hasConceptScore W4288060276C190385971 @default.
- W4288060276 hasConceptScore W4288060276C2776641880 @default.
- W4288060276 hasConceptScore W4288060276C2776867660 @default.
- W4288060276 hasConceptScore W4288060276C2780051608 @default.
- W4288060276 hasConceptScore W4288060276C2780733359 @default.
- W4288060276 hasConceptScore W4288060276C3017944768 @default.
- W4288060276 hasConceptScore W4288060276C70410870 @default.
- W4288060276 hasConceptScore W4288060276C71924100 @default.
- W4288060276 hasConceptScore W4288060276C99454951 @default.
- W4288060276 hasLocation W42880602761 @default.
- W4288060276 hasLocation W42880602762 @default.
- W4288060276 hasOpenAccess W4288060276 @default.
- W4288060276 hasPrimaryLocation W42880602761 @default.
- W4288060276 hasRelatedWork W1742870436 @default.
- W4288060276 hasRelatedWork W1964307545 @default.
- W4288060276 hasRelatedWork W1976379773 @default.
- W4288060276 hasRelatedWork W1977630765 @default.
- W4288060276 hasRelatedWork W2002480798 @default.
- W4288060276 hasRelatedWork W2015183759 @default.
- W4288060276 hasRelatedWork W2018088591 @default.
- W4288060276 hasRelatedWork W2352219946 @default.
- W4288060276 hasRelatedWork W2360616124 @default.
- W4288060276 hasRelatedWork W2808062816 @default.
- W4288060276 isParatext "false" @default.
- W4288060276 isRetracted "false" @default.
- W4288060276 workType "article" @default.