Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288066198> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W4288066198 abstract "The aim of this study was to characterize a large cohort of patients presenting to a single referral center for limbal stem cell deficiency (LSCD).A retrospective chart review of all patients with a clinical diagnosis of LSCD from 2002 to 2015 was performed. Demographics, etiology, previous ocular surgeries, visual acuity, and treatment were assessed.Seven hundred thirty-eight eyes of 434 patients (51.4% male subjects) were diagnosed with LSCD. The mean presenting age was 42.9 years, 70% presented with bilateral disease, and overall vision was poor. The most common etiologies were congenital aniridia (30.9%), chemical or thermal injuries (20.6%), contact lens (16.8%), Stevens-Johnson syndrome (SJS, 10.4%), and iatrogenic (7.3%). Congenital aniridia had a significantly increased association with glaucoma or ocular hypertension (P < 0.0001). Chemical or thermal injuries (P = 0.0007), SJS (P < 0.0001), and mucous membrane pemphigoid (P < 0.0001) had a significantly increased association with eyelid pathology. The mean logMAR best corrected visual acuity (analysis excluded eyes with light perception and no light perception) at presentation was 1.145 (∼20/280). Keratoplasty performed (before presentation at our center) without first addressing the LSCD was seen in 80 eyes; all keratoplasties failed due to recurrence of the LSCD.Patients presenting with LSCD were on average middle aged without sex predominance. LSCD was most commonly bilateral, comprised a wide range of etiologies, and decreased vision substantially. Ocular comorbidities may need to be treated before treating the LSCD surgically. Finally, not addressing the LSCD (primary issue) first can result in keratoplasty failure." @default.
- W4288066198 created "2022-07-28" @default.
- W4288066198 creator A5000462894 @default.
- W4288066198 creator A5029213646 @default.
- W4288066198 creator A5039587323 @default.
- W4288066198 creator A5065306158 @default.
- W4288066198 creator A5071662757 @default.
- W4288066198 creator A5088778313 @default.
- W4288066198 date "2021-05-27" @default.
- W4288066198 modified "2023-10-03" @default.
- W4288066198 title "Limbal Stem Cell Deficiency" @default.
- W4288066198 doi "https://doi.org/10.1097/ico.0000000000002770" @default.
- W4288066198 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34050070" @default.
- W4288066198 hasPublicationYear "2021" @default.
- W4288066198 type Work @default.
- W4288066198 citedByCount "9" @default.
- W4288066198 countsByYear W42880661982021 @default.
- W4288066198 countsByYear W42880661982022 @default.
- W4288066198 countsByYear W42880661982023 @default.
- W4288066198 crossrefType "journal-article" @default.
- W4288066198 hasAuthorship W4288066198A5000462894 @default.
- W4288066198 hasAuthorship W4288066198A5029213646 @default.
- W4288066198 hasAuthorship W4288066198A5039587323 @default.
- W4288066198 hasAuthorship W4288066198A5065306158 @default.
- W4288066198 hasAuthorship W4288066198A5071662757 @default.
- W4288066198 hasAuthorship W4288066198A5088778313 @default.
- W4288066198 hasConcept C104317684 @default.
- W4288066198 hasConcept C118487528 @default.
- W4288066198 hasConcept C137627325 @default.
- W4288066198 hasConcept C141071460 @default.
- W4288066198 hasConcept C142724271 @default.
- W4288066198 hasConcept C185592680 @default.
- W4288066198 hasConcept C2776608714 @default.
- W4288066198 hasConcept C2776882836 @default.
- W4288066198 hasConcept C2778155685 @default.
- W4288066198 hasConcept C2778257484 @default.
- W4288066198 hasConcept C2779257441 @default.
- W4288066198 hasConcept C55493867 @default.
- W4288066198 hasConcept C71924100 @default.
- W4288066198 hasConceptScore W4288066198C104317684 @default.
- W4288066198 hasConceptScore W4288066198C118487528 @default.
- W4288066198 hasConceptScore W4288066198C137627325 @default.
- W4288066198 hasConceptScore W4288066198C141071460 @default.
- W4288066198 hasConceptScore W4288066198C142724271 @default.
- W4288066198 hasConceptScore W4288066198C185592680 @default.
- W4288066198 hasConceptScore W4288066198C2776608714 @default.
- W4288066198 hasConceptScore W4288066198C2776882836 @default.
- W4288066198 hasConceptScore W4288066198C2778155685 @default.
- W4288066198 hasConceptScore W4288066198C2778257484 @default.
- W4288066198 hasConceptScore W4288066198C2779257441 @default.
- W4288066198 hasConceptScore W4288066198C55493867 @default.
- W4288066198 hasConceptScore W4288066198C71924100 @default.
- W4288066198 hasLocation W42880661981 @default.
- W4288066198 hasLocation W42880661982 @default.
- W4288066198 hasOpenAccess W4288066198 @default.
- W4288066198 hasPrimaryLocation W42880661981 @default.
- W4288066198 hasRelatedWork W1586374228 @default.
- W4288066198 hasRelatedWork W2003938723 @default.
- W4288066198 hasRelatedWork W2047967234 @default.
- W4288066198 hasRelatedWork W2118496982 @default.
- W4288066198 hasRelatedWork W2364998975 @default.
- W4288066198 hasRelatedWork W2369162477 @default.
- W4288066198 hasRelatedWork W2439875401 @default.
- W4288066198 hasRelatedWork W3002986063 @default.
- W4288066198 hasRelatedWork W4238867864 @default.
- W4288066198 hasRelatedWork W2525756941 @default.
- W4288066198 hasVolume "Publish Ahead of Print" @default.
- W4288066198 isParatext "false" @default.
- W4288066198 isRetracted "false" @default.
- W4288066198 workType "article" @default.