FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288066293> ?p ?o ?g. }

• W4288066293 endingPage "e539" @default.
• W4288066293 startingPage "e533" @default.
• W4288066293 abstract "This article describes an updated stepwise algorithm for the pharmacological management of osteoarthritis (OA) to establish a treatment method for patients with OA.In step 1, background maintenance therapy includes symptomatic slow-acting drugs for OA, especially prescription crystalline glucosamine sulfate product, for which the high-quality evidence base of efficacy is unequivocal, or prescription chondroitin sulfate. Oral nonsteroidal anti-inflammatory drugs (NSAIDs) or paracetamol only as rescue analgesia is given on top of the background therapy. Step 2: For patients with persistent OA symptoms, the use of oral NSAIDs is mandatory for maintaining supportive therapy with symptomatic slow-acting drugs for OA. It is recommended to properly stratify patients and carefully select oral NSAID therapy to maximize the benefit-to-risk ratio. Intra-articular hyaluronic acid and intra-articular corticosteroids are recommended as well in step 2 of the algorithm, especially for patients who do not respond to the previous therapies. Step 3: Duloxetine is considered along with the previous procedures, especially in patients with pain from central sensitization. Step 4: Total joint replacement is recommended for patients with severe symptoms and poor quality of life.The current guidelines and literature review provide evidence-based recommendations supported by clinical experience on how to organize the treatment process in patients with knee OA applicable in the Russian clinical practice.International evidence-based guidelines lack consensus on different treatments, including the use of prescription crystalline glucosamine sulfate, NSAIDs, and intra-articular hyaluronic acid. The content of this article needs a further discussion about the clinical evidence and harmonization of recommendations for knee OA management." @default.
• W4288066293 created "2022-07-28" @default.
• W4288066293 creator A5005419725 @default.
• W4288066293 creator A5008045147 @default.
• W4288066293 creator A5010020828 @default.
• W4288066293 creator A5017571563 @default.
• W4288066293 creator A5028564130 @default.
• W4288066293 creator A5030711955 @default.
• W4288066293 creator A5035808745 @default.
• W4288066293 creator A5048304785 @default.
• W4288066293 creator A5057150338 @default.
• W4288066293 creator A5088188130 @default.
• W4288066293 date "2020-07-27" @default.
• W4288066293 modified "2023-09-29" @default.
• W4288066293 title "Pharmacological Management of Osteoarthritis With a Focus on Symptomatic Slow-Acting Drugs" @default.
• W4288066293 cites W1599185368 @default.
• W4288066293 cites W1678513801 @default.
• W4288066293 cites W1950509440 @default.
• W4288066293 cites W1984658180 @default.
• W4288066293 cites W1986578760 @default.
• W4288066293 cites W1988567531 @default.
• W4288066293 cites W1993523958 @default.
• W4288066293 cites W2002218955 @default.
• W4288066293 cites W2010818945 @default.
• W4288066293 cites W2025266935 @default.
• W4288066293 cites W2026609781 @default.
• W4288066293 cites W2028355663 @default.
• W4288066293 cites W2032776363 @default.
• W4288066293 cites W2035833931 @default.
• W4288066293 cites W2036491373 @default.
• W4288066293 cites W2037370476 @default.
• W4288066293 cites W2054994464 @default.
• W4288066293 cites W2068436809 @default.
• W4288066293 cites W2069148797 @default.
• W4288066293 cites W2074339153 @default.
• W4288066293 cites W2084289720 @default.
• W4288066293 cites W2088810278 @default.
• W4288066293 cites W2092422416 @default.
• W4288066293 cites W2106059946 @default.
• W4288066293 cites W2113853411 @default.
• W4288066293 cites W2115805053 @default.
• W4288066293 cites W2115814477 @default.
• W4288066293 cites W2122435770 @default.
• W4288066293 cites W2130513475 @default.
• W4288066293 cites W2130761860 @default.
• W4288066293 cites W2153862724 @default.
• W4288066293 cites W2160331588 @default.
• W4288066293 cites W2161518531 @default.
• W4288066293 cites W2161736885 @default.
• W4288066293 cites W2164287243 @default.
• W4288066293 cites W2164863281 @default.
• W4288066293 cites W2188931165 @default.
• W4288066293 cites W2616167388 @default.
• W4288066293 cites W2773194329 @default.
• W4288066293 cites W2902565882 @default.
• W4288066293 cites W2905782592 @default.
• W4288066293 cites W2912783384 @default.
• W4288066293 cites W838020216 @default.
• W4288066293 doi "https://doi.org/10.1097/rhu.0000000000001507" @default.
• W4288066293 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32732520" @default.
• W4288066293 hasPublicationYear "2020" @default.
• W4288066293 type Work @default.
• W4288066293 citedByCount "9" @default.
• W4288066293 countsByYear W42880662932020 @default.
• W4288066293 countsByYear W42880662932021 @default.
• W4288066293 countsByYear W42880662932022 @default.
• W4288066293 countsByYear W42880662932023 @default.
• W4288066293 crossrefType "journal-article" @default.
• W4288066293 hasAuthorship W4288066293A5005419725 @default.
• W4288066293 hasAuthorship W4288066293A5008045147 @default.
• W4288066293 hasAuthorship W4288066293A5010020828 @default.
• W4288066293 hasAuthorship W4288066293A5017571563 @default.
• W4288066293 hasAuthorship W4288066293A5028564130 @default.
• W4288066293 hasAuthorship W4288066293A5030711955 @default.
• W4288066293 hasAuthorship W4288066293A5035808745 @default.
• W4288066293 hasAuthorship W4288066293A5048304785 @default.
• W4288066293 hasAuthorship W4288066293A5057150338 @default.
• W4288066293 hasAuthorship W4288066293A5088188130 @default.
• W4288066293 hasConcept C105702510 @default.
• W4288066293 hasConcept C126322002 @default.
• W4288066293 hasConcept C142724271 @default.
• W4288066293 hasConcept C153074725 @default.
• W4288066293 hasConcept C159110408 @default.
• W4288066293 hasConcept C177713679 @default.
• W4288066293 hasConcept C178790620 @default.
• W4288066293 hasConcept C185592680 @default.
• W4288066293 hasConcept C1862650 @default.
• W4288066293 hasConcept C204787440 @default.
• W4288066293 hasConcept C2426938 @default.
• W4288066293 hasConcept C2776164576 @default.
• W4288066293 hasConcept C2778125326 @default.
• W4288066293 hasConcept C2778484676 @default.
• W4288066293 hasConcept C2779553658 @default.
• W4288066293 hasConcept C2779951463 @default.
• W4288066293 hasConcept C535046627 @default.
• W4288066293 hasConcept C71924100 @default.
• W4288066293 hasConcept C98274493 @default.
• W4288066293 hasConceptScore W4288066293C105702510 @default.

• next