Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288070061> ?p ?o ?g. }
- W4288070061 endingPage "43" @default.
- W4288070061 startingPage "35" @default.
- W4288070061 abstract "The gut microbiome seems to play a role in migraines through increasing intestinal epithelial permeability and pro-inflammatory processes. The associations between the gut microbiome and migraines are uncertain in children.The purpose of this quantitative study was to examine the associations between the gut microbiome and migraines in children aged 7-18 years from the American Gut Project (AGP).A cohort of children aged 7-18 years from the AGP was analyzed. 16S rRNA V4 gene sequences for the gut microbiome, migraines, and demographics were obtained from the AGP Public Repository. After quality control of 16S rRNA gene sequences, α-diversity (Shannon, Faith's_PD, and evenness) and β-diversity metrics (Bray-Curtis and weighted-UniFrac distances), taxonomy, and abundance analyses were implemented using QIIME 2.In total, 381 children (341 without migraines; 40 with professional or self-diagnosed migraines) were analyzed with a mean age of 11.5 years. Compared with those without migraines, children with migraines showed lower estimates in Shannon and Faith's_PD (p < .01). Both Bray-Curtis and weighted-UniFrac distances displayed the gut microbial dissimilarities between these two groups (p = .001). Children with migraines had higher abundances in genus of phylum Bacteroidetes (Bacteroides, Parabacteroides, Odoribacter), Actinobacteria (Eggerthella, Varibaculum), Firmicutes (SMB53, Lachnospira, Dorea, Veillonella, Anaerotruncus, Butyricicoccus, Coprobacillus, Eubacterium), and Proteobacteria (Sutterella) than children without migraines.Associations of the gut microbiome diversity and abundances with migraines in children indicated potential biological mechanisms of migraines. Future work needs to confirm our findings in children." @default.
- W4288070061 created "2022-07-28" @default.
- W4288070061 creator A5017164999 @default.
- W4288070061 creator A5028457429 @default.
- W4288070061 creator A5089790890 @default.
- W4288070061 date "2023-02-01" @default.
- W4288070061 modified "2023-10-17" @default.
- W4288070061 title "Associations between the Gut Microbiome and Migraines in Children Aged 7-18 Years: An Analysis of the American Gut Project Cohort" @default.
- W4288070061 cites W1523266228 @default.
- W4288070061 cites W1574625282 @default.
- W4288070061 cites W1577764493 @default.
- W4288070061 cites W1975008426 @default.
- W4288070061 cites W1980475824 @default.
- W4288070061 cites W1984474722 @default.
- W4288070061 cites W1990409301 @default.
- W4288070061 cites W2029943794 @default.
- W4288070061 cites W2047790077 @default.
- W4288070061 cites W2050920580 @default.
- W4288070061 cites W2083501377 @default.
- W4288070061 cites W2089246633 @default.
- W4288070061 cites W2093969663 @default.
- W4288070061 cites W2097515723 @default.
- W4288070061 cites W2102278586 @default.
- W4288070061 cites W2114405499 @default.
- W4288070061 cites W2122729131 @default.
- W4288070061 cites W2125784987 @default.
- W4288070061 cites W2132689324 @default.
- W4288070061 cites W2136759951 @default.
- W4288070061 cites W2143777796 @default.
- W4288070061 cites W2149351690 @default.
- W4288070061 cites W2149756110 @default.
- W4288070061 cites W2152589784 @default.
- W4288070061 cites W2157800726 @default.
- W4288070061 cites W2158795865 @default.
- W4288070061 cites W2167084464 @default.
- W4288070061 cites W2168249366 @default.
- W4288070061 cites W2171742795 @default.
- W4288070061 cites W2275060907 @default.
- W4288070061 cites W2324431491 @default.
- W4288070061 cites W2401404581 @default.
- W4288070061 cites W2521421819 @default.
- W4288070061 cites W2535282914 @default.
- W4288070061 cites W2539358968 @default.
- W4288070061 cites W2548957578 @default.
- W4288070061 cites W2625207619 @default.
- W4288070061 cites W2728654001 @default.
- W4288070061 cites W2751128104 @default.
- W4288070061 cites W2769664962 @default.
- W4288070061 cites W2791816815 @default.
- W4288070061 cites W2792451891 @default.
- W4288070061 cites W2794407684 @default.
- W4288070061 cites W2804866899 @default.
- W4288070061 cites W2900637714 @default.
- W4288070061 cites W2901391352 @default.
- W4288070061 cites W2909305492 @default.
- W4288070061 cites W2940790373 @default.
- W4288070061 cites W2963276645 @default.
- W4288070061 cites W2964629419 @default.
- W4288070061 cites W2969455443 @default.
- W4288070061 cites W2970310193 @default.
- W4288070061 cites W2982359845 @default.
- W4288070061 cites W2995754610 @default.
- W4288070061 cites W3004327143 @default.
- W4288070061 cites W3006647806 @default.
- W4288070061 cites W3093405588 @default.
- W4288070061 cites W3096439433 @default.
- W4288070061 cites W3181075422 @default.
- W4288070061 cites W3185704445 @default.
- W4288070061 cites W3199355847 @default.
- W4288070061 cites W3200478667 @default.
- W4288070061 cites W637138851 @default.
- W4288070061 doi "https://doi.org/10.1016/j.pmn.2022.06.002" @default.
- W4288070061 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35907763" @default.
- W4288070061 hasPublicationYear "2023" @default.
- W4288070061 type Work @default.
- W4288070061 citedByCount "4" @default.
- W4288070061 countsByYear W42880700612023 @default.
- W4288070061 crossrefType "journal-article" @default.
- W4288070061 hasAuthorship W4288070061A5017164999 @default.
- W4288070061 hasAuthorship W4288070061A5028457429 @default.
- W4288070061 hasAuthorship W4288070061A5089790890 @default.
- W4288070061 hasConcept C143121216 @default.
- W4288070061 hasConcept C151437367 @default.
- W4288070061 hasConcept C2777385719 @default.
- W4288070061 hasConcept C2777695942 @default.
- W4288070061 hasConcept C2778169975 @default.
- W4288070061 hasConcept C2779676784 @default.
- W4288070061 hasConcept C2780027724 @default.
- W4288070061 hasConcept C2780092757 @default.
- W4288070061 hasConcept C42062724 @default.
- W4288070061 hasConcept C523546767 @default.
- W4288070061 hasConcept C54355233 @default.
- W4288070061 hasConcept C60644358 @default.
- W4288070061 hasConcept C71924100 @default.
- W4288070061 hasConcept C86803240 @default.
- W4288070061 hasConceptScore W4288070061C143121216 @default.
- W4288070061 hasConceptScore W4288070061C151437367 @default.
- W4288070061 hasConceptScore W4288070061C2777385719 @default.