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• W4288070859 abstract "An important part of the rehabilitation process in children with autism is the search for effective methods that affect the main pathogenetic mechanisms. Aim. To evaluate the effect of dolphin therapy (DT) on the monoaminergic and hormonal systems in children with autism spectrum disorders (ASD). Material and methods. 47 children with ASD – (F84) aged 3 to 14 years were examined. The I group – 23 children who received the basic sanatorium-resort treatment (SRT); the II group – 24 children got a course of DT. The checkup included examination by specialists, evaluation of serotonin, norepinephrine and cortisol in the blood serum before and after the treatment complexes. Results and discussion. There was a significant decrease in serotonin and norepinephrine, an increase in cortisol in children with ASD. After the treatment, there was a significant increase in norepinephrine levels and decrease in cortisol with an average degree of ASD in the group I, increasing in serotonin, norepinephrine and decrease in cortisol with all degrees of ASD severity in the II group. Many mental disorders are controlled not by the levels of serotonin and norepinephrine, but by their balance in content. The conducted basic SRT increases the level of norepinephrine and reduces the cortisol content in children with moderate severity of autism, without affecting severe forms of ASD. The use of DT in the basic HRT contributed to an increase in the content of serotonin and norepinephrine and a decrease in cortisol in moderate and severe autism, which had a positive effect on clinical indicators (manifestations of hyperactivity, phobias, aggression and autoaggression decreased, cognitive abilities, attention, speech functions improved). Conclusions. A close relationship has been established between monoamines and cortisol in children with ASD and their participation in the pathogenetic mechanisms of the disease. The inclusion of the DT in the SRT course contributes to breaking the vicious circle and normalizing the relationship between monoamines and cortisol in children with ASD." @default.
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• W4288070859 date "2022-04-29" @default.
• W4288070859 modified "2023-10-14" @default.
• W4288070859 title "Dynamics of Neuromodulatory and Hormonal Systems in Children with Autism Spectrum Disorders under the Dolphin Therapy Influence" @default.
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• W4288070859 doi "https://doi.org/10.38025/2078-1962-2022-21-2-108-114" @default.
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