FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288439462> ?p ?o ?g. }

• W4288439462 endingPage "15" @default.
• W4288439462 startingPage "1" @default.
• W4288439462 abstract "The current high mortality rate of female breast cancer (BC) patients emphasizes the necessity of identifying powerful and reliable prognostic signatures in BC patients. Epithelial-mesenchymal transition (EMT) was reported to be associated with the development of BC. The purpose of this study was to identify prognostic biomarkers that predict overall survival (OS) in female BC patients by integrating data from TCGA database.We first downloaded the dataset in TCGA and identified gene signatures by overlapping candidate genes. Differential analysis was performed to find differential EMT-related genes. Univariate regression analysis was then performed to identify candidate prognostic variables. We then developed a prognostic model by multivariate analysis to predict OS. Calibration curves, receiver operating characteristics (ROC) curves, C-index, and decision curve analysis (DCA) were used to test the veracity of the prognostic model.In this study, we identified and validated a prognostic model integrating age and six genes (CD44, P3H1, SDC1, COL4A1, TGFβ1, and SERPINE1). C-index values for BC patients were 0.672 (95% CI 0.611-0.732) and 0.692 (95% CI 0.586-0.798) in the training cohort and test set, respectively. The calibration curve and the DCA curve show the good predictive performance of the model.This study offered a robust predictive model for OS prediction in female BC patients and may provide a more accurate treatment strategy and personalized therapy in the future." @default.
• W4288439462 created "2022-07-29" @default.
• W4288439462 creator A5011156931 @default.
• W4288439462 creator A5020473726 @default.
• W4288439462 creator A5030620196 @default.
• W4288439462 creator A5037018453 @default.
• W4288439462 creator A5038042341 @default.
• W4288439462 creator A5086536116 @default.
• W4288439462 creator A5088277165 @default.
• W4288439462 date "2022-07-28" @default.
• W4288439462 modified "2023-10-16" @default.
• W4288439462 title "Establishment and Analysis of an Individualized EMT-Related Gene Signature for the Prognosis of Breast Cancer in Female Patients" @default.
• W4288439462 cites W2008749520 @default.
• W4288439462 cites W2034271653 @default.
• W4288439462 cites W2552235514 @default.
• W4288439462 cites W2617077704 @default.
• W4288439462 cites W2770397194 @default.
• W4288439462 cites W2786427149 @default.
• W4288439462 cites W2795478721 @default.
• W4288439462 cites W2885823461 @default.
• W4288439462 cites W2906067435 @default.
• W4288439462 cites W2909893490 @default.
• W4288439462 cites W2912828651 @default.
• W4288439462 cites W2940057770 @default.
• W4288439462 cites W2963593504 @default.
• W4288439462 cites W2967901922 @default.
• W4288439462 cites W2973063228 @default.
• W4288439462 cites W2982643407 @default.
• W4288439462 cites W2988353924 @default.
• W4288439462 cites W3002014546 @default.
• W4288439462 cites W3007238405 @default.
• W4288439462 cites W3016588471 @default.
• W4288439462 cites W3024233690 @default.
• W4288439462 cites W3025152879 @default.
• W4288439462 cites W3048942453 @default.
• W4288439462 cites W3087046772 @default.
• W4288439462 cites W3110253137 @default.
• W4288439462 cites W3111963281 @default.
• W4288439462 cites W3118696677 @default.
• W4288439462 cites W3124226459 @default.
• W4288439462 cites W3124893280 @default.
• W4288439462 cites W3136229381 @default.
• W4288439462 cites W3148384893 @default.
• W4288439462 cites W3159496914 @default.
• W4288439462 cites W3162286381 @default.
• W4288439462 cites W3177620586 @default.
• W4288439462 cites W4210510513 @default.
• W4288439462 cites W4211032970 @default.
• W4288439462 cites W4211063456 @default.
• W4288439462 cites W4220725470 @default.
• W4288439462 cites W4220728308 @default.
• W4288439462 cites W4220786382 @default.
• W4288439462 cites W4220982142 @default.
• W4288439462 doi "https://doi.org/10.1155/2022/1289445" @default.
• W4288439462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35937944" @default.
• W4288439462 hasPublicationYear "2022" @default.
• W4288439462 type Work @default.
• W4288439462 citedByCount "3" @default.
• W4288439462 countsByYear W42884394622023 @default.
• W4288439462 crossrefType "journal-article" @default.
• W4288439462 hasAuthorship W4288439462A5011156931 @default.
• W4288439462 hasAuthorship W4288439462A5020473726 @default.
• W4288439462 hasAuthorship W4288439462A5030620196 @default.
• W4288439462 hasAuthorship W4288439462A5037018453 @default.
• W4288439462 hasAuthorship W4288439462A5038042341 @default.
• W4288439462 hasAuthorship W4288439462A5086536116 @default.
• W4288439462 hasAuthorship W4288439462A5088277165 @default.
• W4288439462 hasBestOaLocation W42884394621 @default.
• W4288439462 hasConcept C10515644 @default.
• W4288439462 hasConcept C119857082 @default.
• W4288439462 hasConcept C121608353 @default.
• W4288439462 hasConcept C126322002 @default.
• W4288439462 hasConcept C143998085 @default.
• W4288439462 hasConcept C144301174 @default.
• W4288439462 hasConcept C161584116 @default.
• W4288439462 hasConcept C199163554 @default.
• W4288439462 hasConcept C38180746 @default.
• W4288439462 hasConcept C41008148 @default.
• W4288439462 hasConcept C530470458 @default.
• W4288439462 hasConcept C58471807 @default.
• W4288439462 hasConcept C60644358 @default.
• W4288439462 hasConcept C71924100 @default.
• W4288439462 hasConcept C86803240 @default.
• W4288439462 hasConceptScore W4288439462C10515644 @default.
• W4288439462 hasConceptScore W4288439462C119857082 @default.
• W4288439462 hasConceptScore W4288439462C121608353 @default.
• W4288439462 hasConceptScore W4288439462C126322002 @default.
• W4288439462 hasConceptScore W4288439462C143998085 @default.
• W4288439462 hasConceptScore W4288439462C144301174 @default.
• W4288439462 hasConceptScore W4288439462C161584116 @default.
• W4288439462 hasConceptScore W4288439462C199163554 @default.
• W4288439462 hasConceptScore W4288439462C38180746 @default.
• W4288439462 hasConceptScore W4288439462C41008148 @default.
• W4288439462 hasConceptScore W4288439462C530470458 @default.
• W4288439462 hasConceptScore W4288439462C58471807 @default.
• W4288439462 hasConceptScore W4288439462C60644358 @default.
• W4288439462 hasConceptScore W4288439462C71924100 @default.
• W4288439462 hasConceptScore W4288439462C86803240 @default.

• next