Matches in SemOpenAlex for { <https://semopenalex.org/work/W4288458712> ?p ?o ?g. }
- W4288458712 endingPage "577936" @default.
- W4288458712 startingPage "577936" @default.
- W4288458712 abstract "Connective tissue growth factor (CTGF/CCN2) is a proinflammatory and an oligodendrocyte-differentiating blocking agent. It is found in MS lesions, which raises the possibility of involvement in MS pathogenesis. We found that its CSF and serum levels were higher in RR-MS patients than in controls and for serum compared to PP and SP-MS. Immune cells of both RR-MS and controls secreted CTGF/CCN2, which was enhanced by CD3/CD28 stimulation or by LPS. Anti-CTGF treatment of mice with experimental autoimmune encephalitis ameliorated its clinical severity. CTGF/CCN2 may play a role in the immune pathogenesis of MS and in remyelination failure in early stages of MS." @default.
- W4288458712 created "2022-07-29" @default.
- W4288458712 creator A5007888991 @default.
- W4288458712 creator A5009130148 @default.
- W4288458712 creator A5011400225 @default.
- W4288458712 creator A5051610403 @default.
- W4288458712 creator A5053688784 @default.
- W4288458712 creator A5056731983 @default.
- W4288458712 creator A5062222775 @default.
- W4288458712 creator A5068912776 @default.
- W4288458712 creator A5069898283 @default.
- W4288458712 creator A5079821773 @default.
- W4288458712 creator A5086719347 @default.
- W4288458712 creator A5088512021 @default.
- W4288458712 creator A5089769843 @default.
- W4288458712 date "2022-10-01" @default.
- W4288458712 modified "2023-10-01" @default.
- W4288458712 title "CTGF/CCN2 has a possible detrimental role in the inflammation and the remyelination failure in the early stages of multiple sclerosis" @default.
- W4288458712 cites W1828576284 @default.
- W4288458712 cites W1834417670 @default.
- W4288458712 cites W1842548364 @default.
- W4288458712 cites W1866034006 @default.
- W4288458712 cites W1921871464 @default.
- W4288458712 cites W1971318940 @default.
- W4288458712 cites W1979034244 @default.
- W4288458712 cites W1980747513 @default.
- W4288458712 cites W1986173197 @default.
- W4288458712 cites W1988718047 @default.
- W4288458712 cites W2011785169 @default.
- W4288458712 cites W2012053263 @default.
- W4288458712 cites W2016035349 @default.
- W4288458712 cites W2016801472 @default.
- W4288458712 cites W2019710745 @default.
- W4288458712 cites W2026541524 @default.
- W4288458712 cites W2038585115 @default.
- W4288458712 cites W2045762174 @default.
- W4288458712 cites W2049565893 @default.
- W4288458712 cites W2052724168 @default.
- W4288458712 cites W2058358434 @default.
- W4288458712 cites W2059427623 @default.
- W4288458712 cites W2062326815 @default.
- W4288458712 cites W2088613090 @default.
- W4288458712 cites W2094044389 @default.
- W4288458712 cites W2098589841 @default.
- W4288458712 cites W2110898038 @default.
- W4288458712 cites W2113948549 @default.
- W4288458712 cites W2115820646 @default.
- W4288458712 cites W2128757614 @default.
- W4288458712 cites W2132561478 @default.
- W4288458712 cites W2142747843 @default.
- W4288458712 cites W2145927791 @default.
- W4288458712 cites W2169525455 @default.
- W4288458712 cites W2171108041 @default.
- W4288458712 cites W2341087026 @default.
- W4288458712 cites W2586431064 @default.
- W4288458712 cites W2735112771 @default.
- W4288458712 cites W2777074421 @default.
- W4288458712 cites W2909270098 @default.
- W4288458712 cites W2951427869 @default.
- W4288458712 cites W3197136220 @default.
- W4288458712 cites W4224092693 @default.
- W4288458712 cites W4247304472 @default.
- W4288458712 doi "https://doi.org/10.1016/j.jneuroim.2022.577936" @default.
- W4288458712 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35926331" @default.
- W4288458712 hasPublicationYear "2022" @default.
- W4288458712 type Work @default.
- W4288458712 citedByCount "1" @default.
- W4288458712 countsByYear W42884587122023 @default.
- W4288458712 crossrefType "journal-article" @default.
- W4288458712 hasAuthorship W4288458712A5007888991 @default.
- W4288458712 hasAuthorship W4288458712A5009130148 @default.
- W4288458712 hasAuthorship W4288458712A5011400225 @default.
- W4288458712 hasAuthorship W4288458712A5051610403 @default.
- W4288458712 hasAuthorship W4288458712A5053688784 @default.
- W4288458712 hasAuthorship W4288458712A5056731983 @default.
- W4288458712 hasAuthorship W4288458712A5062222775 @default.
- W4288458712 hasAuthorship W4288458712A5068912776 @default.
- W4288458712 hasAuthorship W4288458712A5069898283 @default.
- W4288458712 hasAuthorship W4288458712A5079821773 @default.
- W4288458712 hasAuthorship W4288458712A5086719347 @default.
- W4288458712 hasAuthorship W4288458712A5088512021 @default.
- W4288458712 hasAuthorship W4288458712A5089769843 @default.
- W4288458712 hasConcept C126322002 @default.
- W4288458712 hasConcept C142724271 @default.
- W4288458712 hasConcept C164027704 @default.
- W4288458712 hasConcept C170493617 @default.
- W4288458712 hasConcept C203014093 @default.
- W4288458712 hasConcept C2775960820 @default.
- W4288458712 hasConcept C2776914184 @default.
- W4288458712 hasConcept C2776985911 @default.
- W4288458712 hasConcept C2777619251 @default.
- W4288458712 hasConcept C2778609137 @default.
- W4288458712 hasConcept C2780631158 @default.
- W4288458712 hasConcept C2780640218 @default.
- W4288458712 hasConcept C2780942790 @default.
- W4288458712 hasConcept C518705261 @default.
- W4288458712 hasConcept C529278444 @default.
- W4288458712 hasConcept C71924100 @default.