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- W4288514372 abstract "Abstract Background Hospital volume has emerged as a prognostic factor in oncology but is not currently known whether volume is associated with improved outcomes for cutaneous head and neck (HN) melanoma. Methods A total of 556 079 cutaneous melanoma cases reported by the 2004–2016 National Cancer Database were separated into two cohorts (HN and non‐HN) and facilities within each cohort were classified by case volume. Analysis employed chi‐square, analysis of variance, Kaplan–Meier, and Cox proportional hazards models. Results Only 41 facilities (3.1% of 1326) treating HN melanoma and 50 facilities (3.7% of 1344) treating non‐HN melanoma were classified as high‐volume facilities (HVFs). The estimated 5‐year overall survival (OS) was 62.7% (standard error [SE]: 0.4%) for patients with HN at low‐volume facilities (LVFs), 69.3% (SE: 0.4%) at IVFs, and 71.8% (SE 0.4%) at HVFs ( p < 0.001). Differences in OS remained significant between HVFs versus LVFs after adjusting for confounders. Conclusion Volume is independently associated with OS and improved surgical outcomes for HN melanoma." @default.
- W4288514372 created "2022-07-29" @default.
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- W4288514372 date "2022-07-29" @default.
- W4288514372 modified "2023-09-26" @default.
- W4288514372 title "Case volume regionalization and <scp>volume‐based</scp> outcome differences in cutaneous head and neck melanoma" @default.
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- W4288514372 doi "https://doi.org/10.1002/hed.27150" @default.
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