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- W4288704144 abstract "Abstract Intestinal metabolites are attracting increasing interest, especially more and more studies have found they are closely related to diseases. Microbial fermentation of indigestible dietary fibers in the gut produces short chain fatty acids (SCFAs) as the main product. SCFAs can exert influences on the integrity of the intestinal epithelial and mucosal barrier, immune reactions, and the diversity of microbiota in humans. Thus, alteration in SCFAs may affect inflammatory bowel disease (IBD). In IBD, SCFAs are involved in the main pathogenic process and play an important role in the development of intestinal inflammation. Although many studies have proved that pretreatment with SCFAs can effectively ameliorate inflammation in the gut, the mechanisms are not fully understood. In this review, we describe the relationship between SCFAs and IBD from the aspects of defense barrier, immune effects, and microbial alterations. We also summarize the effects of SCFAs on comorbidities in IBD via the gut‐brain, gut‐liver, and gut‐lung axis, and we give an overview of the prospects of their clinical application. A better understanding of the relevance of SCFAs in IBD may reveal novel targets for future study" @default.
- W4288704144 created "2022-07-30" @default.
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- W4288704144 date "2022-08-05" @default.
- W4288704144 modified "2023-10-17" @default.
- W4288704144 title "Short‐chain fatty acids affect the development of inflammatory bowel disease through intestinal barrier, immunology, and microbiota: A promising therapy?" @default.
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- W4288704144 cites W1992431640 @default.
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- W4288704144 cites W2002703043 @default.
- W4288704144 cites W2007278577 @default.
- W4288704144 cites W2010724120 @default.
- W4288704144 cites W2022804237 @default.
- W4288704144 cites W2043221183 @default.
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- W4288704144 doi "https://doi.org/10.1111/jgh.15970" @default.
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